Evidence for the Existence of a Soybean Resistant Protein That Captures Bile Acid and Stimulates Its Fecal Excretion
スポンサーリンク
概要
- 論文の詳細を見る
Feeding HMF, an insoluble “high-molecular-weight fraction” from an industrial enzymatic digest of a soy protein isolate, increased the fecal excretion of bile acid concomitant with increased fecal nitrogen. An amino acid analysis revealed that this increased fecal nitrogen could be explained by an increase in the insoluble protein fraction. This suggests the existence of an indigestable protein or peptide that can be called a “resistant protein” in the feces. The presumed resistant protein was rich in hydrophobic amino acids and bound bile acid by hydrophobic interaction. The residual fraction of HMF obtained after in vitro pepsin and pancreatin digestion, showed higher in vitro bile acid-binding capacity and excreted more bile acid in vivo than HMF. Its amino acid composition was similar to that of the feces of rat fed with HMF. These results suggest that the fecal resistant protein with bile acid-binding ability could be derived from the indigestable fraction of HMF.
- 社団法人 日本農芸化学会の論文
- 2006-12-23
著者
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Sato Kenji
Department of Anatomy and Physiological Science, Graduate School of Health Care Sciences, Tokyo Medi
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Nakamura Yasushi
Department of Clinical Laboratory Medicine, Wakayama Medical University
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Sato Kenji
Department Of Food Sciences And Nutritional Health Kyoto Prefectural University
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Sato Katsuaki
Central Research Laboratories Of Ajinomoto Co. Inc.
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Nakamura Yoshimasa
Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University
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崎山 高明
Department Of Bioscience And Biotechnology Faculty Of Engineering Okayama University:(present Addres
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Ohtsuki K
Kitasato Univ. Sagamihara Jpn
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Kubota Satoshi
Division Of Human Health And Medical Science Graduate School Of Kuroshio Science Kochi University
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OHTSUKI kozo
Department of Food Science and Nutrition, Kyoto Prefectural University
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HIGAKI Noriko
Department of Biological Resource Chemistry, Kyoto Prefectural University
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SUDA Hitoshi
Department of Biological Resource Chemistry, Kyoto Prefectural University
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SUZUKA Tomohiko
Department of Biological Resource Chemistry, Kyoto Prefectural University
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KOMORI Takeo
Department of Biological Resource Chemistry, Kyoto Prefectural University
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SAEKI Tohru
Department of Biological Resource Chemistry, Kyoto Prefectural University
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IWAMI Kimikazu
Department of Biological Resource Chemistry, Kyoto Prefectural University
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KANAMOTO Ryuhei
Department of Biological Resource Chemistry, Kyoto Prefectural University
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IWAMI Kimikazu
Laboratory of Molecular Nutrition, Kyoto Prefectural University
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KANAMOTO Ryuhei
Laboratory of Molecular Nutrition, Kyoto Prefectural University
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Sato K
Department Of Food Sciences And Nutritional Health Kyoto Prefectural University
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Nakamura Yasushi
Department Of Clinical Laboratory Medicine Wakayama Medical University
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Kubota S
Division Of Human Health And Medical Science Graduate School Of Kuroshio Science Kochi University
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Iwami K
Lab. Of Molecular Nutrition Kyoto Prefectural Univ.
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Komori Takeo
Department Of Biological Resource Chemistry Kyoto Prefectural University
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Suda Hitoshi
Department Of Biological Resource Chemistry Kyoto Prefectural University
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Ohtsuki Kozo
Department Of Food Sciences And Nutritional Health Kyoto Prefectural University
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Ohtsuki Kozo
Department Of Food Science And Nutrition Kyoto Prefectural University
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Higaki Noriko
Department Of Biological Resource Chemistry Kyoto Prefectural University
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Iwami Kimikazu
Department Of Agricultural Chemistry Kyoto Prefectural University
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Kanamoto R
Lab. Of Molecular Nutrition Kyoto Prefectural Univ.
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Kanamoto Ryuhei
Department Of Biological Resource Chemistry Kyoto Prefectural University
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Saeki Tohru
Laboratory Of Molecular Nutrition Kyoto Prefectural University
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Saeki Tohru
Department Of Biological Resource Chemistry Kyoto Prefectural University
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Suzuka Tomohiko
Laboratory Of Molecular Nutrition Kyoto Prefectural University
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Nakamura Yasushi
Department Of Agricultural Chemistry Faculty Of Agriculture Niigata University
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Sato Kenji
Department Of Anatomy And Physiological Science Graduate School Of Health Care Sciences Tokyo Medica
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