Hypocholesterolemic Effect of Chitosan in Adult Males

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概要

• 論文の詳細を見る

• The present study is the first to report the hypocholesterolemic effect of chitosan on humans. When 3-6 g/day of chitosan was given in the diet to 8 healthy males, total serum cholesterol significantly decreased, and when the ingestion was stopped, the value increased to the level before ingestion. Serum HDL-cholesterol was increased significantly by the ingestion of chitosan. The excreted amounts of primary bile acids, cholic acid and chenodeoxycholic acid, into the feces was significantly increased by the ingestion of chitosan, and the amount of cholic acid excretion decreased significantly after the ingestion was stopped. These facts suggest that chitosan combined bile acids in the digestive tract, and that the combined product was excreted into the feces. This, in turn, deceased the resorption of bile acids, so that the cholesterol poool in the body was decreased and the level of serum chrolesterol consequently decreased.

• 社団法人日本農芸化学会の論文
• 1993-09-23

著者

• Yasushi Kawai

  Laboratory Of Animal Products Chemistry Graduate School Of Agricultural Science Tohoku University

• Tsuji Keisuke

  National Institute Of Health And Nutrition

• Nakamura Y

  Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University

• Nakagawa Y

  Graduate School Of Agriculture Kyoto University

• Nakagawa Yu

  Graduate School Of Agriculture Kyoto University

• Kawai Yoshiyuki

  Tokyo Dietitian Academy

• Akimoto Makoto

  Tokyo Dietitian Academy

• Akimoto M

  Hokkaido Forestry Research Inst. Hokkaido Jpn

• Kawai Y

  Kyoto Univ. Kyoto

• Nakagawa Yasue

  Department Of Food Faculty Of Home Economics Jissen Women's University

• MITSUOKA Tomotari

  The Institute of Physical and Chemical Research

• Maezaki Yuji

  Research Laboratories, Pharmaceuticals Group, Nippon Kayaku Co., Ltd.

• Tsuji Keisuke

  The National Institute of Health and Nutrition

• Tsugita Takashi

  Bioscience Research Laboratory, Katokichi Co., Ltd.

• Takekawa Wataru

  Jyoto Kousei Hospital

• Terada Atsushi

  Department of Food Hygiene, Nippon Veterinary and Animal Science University

• Hara Hiroyoshi

  Department of Food Hygiene, Nippon Veterinary and Animal Science University

• Mitsuoka Tomotari

  Department of Food Hygiene, Nippon Veterinary and Animal Science University

• Maezaki Yuji

  Research Laboratories Pharmaceuticals Group Nippon Kayaku Co. Ltd.

• Terada A

  Nippon Veterinary And Animal Sci. Univ. Tokyo Jpn

• Terada Atsushi

  Department Of Electrical And Electronic Engineering Utsunomiya University

• Hara Hiroyoshi

  Department Of Food Hygiene Nippon Veterinary And Animal Science University

• Tsugita Takashi

  Bioscience Research Laboratory Katokichi Co. Ltd.

• Mitsuoka T

  Nippon Veterinary And Animal Sci. Univ. Tokyo Jpn

• Mitsuoka T

  Laboratory Of Veterinary Public Health

• Mitsuoka Tomotari

  Department Of Food Technology Nippon Veterinary And Animal Science University

• Mitsuoka Tomotari

  Department Of Biomedical Science Faculty Of Agriculture The University Of Tokyo

• Mitsuoka Tomotari

  Laboratory Of Veterinary Public Health

• Mitsuoka Tomotari

  Frontier Research Program Laboratory For Intestinal Flora Riken:faculty Of Agriculture The Universit

• Kawai Y

  Faculty Of Fisheries Sciences Hokkaido University

• Nakagawa Yu

  Division Of Food Science And Biotechnology Graduate School Of Agriculture Kyoto University

• Nakagawa Yasue

  Department Of Food And Health Sciences Faculty Of Human Life Sciences Jissen Women's University

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