Irie Kazuhiro | 京都大学農学研究科

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概要

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著作論文

アミロイドβ(Aβ42)の毒性コンホメーションの提唱
P-55 βアミロイドの新しい凝集モデルに基づく神経細胞毒性発現機構(ポスター発表の部)
11 固体NMRならびにESRによるβアミロイド(Aβ42)の毒性コンホメーションの解析(口頭発表の部)
ポリフェノールによるアルツハイマー病予防の可能性
βアミロイドの毒性コンホメーション
26 天然発がんプロモーターの骨格を利用した抗がん剤bryostatin等価体の開発(口頭発表の部)
'Malignant' Conformation of Alzheimer's β Peptides (Aβ42) through Radical Formation
P-64 ELUICIDATION OF THE 'MALIGNATNT' CONFORMATION OF β-AMYLOID WITH ITALIAN MUTATION (E22K-Aβ42) USING SOLID-STATE NMR
P-9 FORMATION AND STABILIZATION MECHANISM OF THE β-AMYLOID RADICAL
Structure of β-Amyloid Fibrils and Its Relevance to Their Neurotoxicity : Implications for the Pathogenesis of Alzheimer's Disease
P-38 ANALYSIS OF CH/π INTERACTION BETWEEN TUMOR PROMOTERS AND PROTEIN KINASE C C1 DOMAINS
New Aggregation Model of Amyloid β by the Systematic Proline Replacement
Identification of Toxic Conformation in Aβ42 Aggregates Using Solid-state NMR
Silymarin Attenuated the Amyloid β Plaque Burden and Improved Behavioral Abnormalities in an Alzheimer's Disease Mouse Model
The turn formation at positions 22 and 23 in the 42-mer amyloid β peptide : The emerging role in the pathogenesis of Alzheimer's disease
Verification of the Intermolecular Parallel β-Sheet in E22K-Aβ42 Aggregates by Solid-State NMR Using Rotational Resonance : Implications for the Supramolecular Arrangement of the Toxic Conformer of Aβ42
CH/π相互作用を利用した薬剤開発(最前線,ポストゲノム時代の有機化学)
Synthesis and Biological Evaluation of the 12,12-Dimethyl Derivative of Aplog-1, an Anti-Proliferative Analog of Tumor-Promoting Aplysiatoxin
33. 気孔形成を調節するペプチドホルモンの機能解析(口頭発表,植物化学調節学会第46回大会)
Stimulation of the Amyloidogenic Pathway by Cytoplasmic Superoxide Radicals in an Alzheimer's Disease Mouse Model
Identification and Biological Activities of Bryostatins from Japanese Bryozoan

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