Antibody to Soluble 1,3/1,6-β-D-Glucan, SCG in Sera of Naive DBA/2 Mice(Miscellaneous)
スポンサーリンク
概要
- 論文の詳細を見る
A branched β-glucan from Sparassis crispa (SCG) is a major 6-branched 1,3-β-D-glucan showing antitumor activity. In the present study, we examined the anti-SCG antibody in naive mice by ELISA. Using SCG coated plate, sera of naive DBA/1 and DBA/2 mice contained significantly higher titers of antibody than other strains of mice. Anti-SCG Ab titers of each DBA/1 and DBA/2 mice were significantly varied. Using various polysaccha-ride-coated plate, sera of DBA/2 mice also reacted with a β-glucan from Candida spp. (CSBG) having 1,3-β and 1,6-β-glucosidic linkages. The SCG specific immunoglobulin (Ig) M but G was detected in sera. The reactivity of sera to coated SCG was neutralized by adding soluble SCG and CSBG as competitor. These results suggested that DBA/1 and DBA/2 strains carry specific and unique immunological characteristics to branched 1,3-/1,6-β-glucan.
- 社団法人日本薬学会の論文
- 2003-08-01
著者
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中島 誠
北海道大学大学院薬学研究科
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中島 正晴
県立食品総合研究所
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ADACHI Yoshiyuki
Laboratory far Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pha
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OHNO Naohito
Laboratory far Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pha
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Ohno Naohito
東京薬科大学 免疫学
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Ohno Naohito
東京薬科大学 薬 微生物
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Ohno Naohito
Lab. For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo Univ. Of Pharmacy And Lif
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Ohno N
Laboratory For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm
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Miura N
Laboratory For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm
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Nagi Miura
Laboratory For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm
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Adachi Yoshiyuki
東京薬科大学 免疫学
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Adachi Y
Tokyo Univ. Pharmacy And Life Sci. Tokyo Jpn
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Adachi Yoshiyuki
Laboratory Far Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm
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HARADA Toshie
Laboratory for Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pha
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NAKAJIMA Mitsuhiro
Minahealth Co., Ltd.
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YADOMAE Toshiro
Laboratory for Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pha
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Adachi Yoshiyuki
Laboratory For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm
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Ohno Naohito
Laboratory Of Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharma
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Ohno Naohito
Laboratory For Immunopharmacology Of Microbial Products Tokyo University Of Pharmacy And Life Scienc
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Nakajima Mitsuhiro
Minahealth Co. Ltd.
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Harada Toshie
Seikagaku Corporation
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Yadomae T
Laboratory For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm
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Harada Toshie
Laboratory For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm
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Nagi Miura
Laboratory For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm
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Ohno Naohito
Laboratory For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm
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