Analysis of Mitogenic Substances in Bupleurum chinense by ESR Spectroscopy
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概要
- 論文の詳細を見る
The polyphenolic substance(s) in the hot water extract of Bupleurum chinese (PSF) showed strong mitogenic activity. In this paper, we analyzed PSF by using ESR spectroscopy, and found that i) PSF showed a strong ESR signal on g=2.005 which was similar to the commercially available lignin; ii) Sho-saiko-to, which contains an extract of B. chinense, also showed similar signals on ESR; iii) Powdered B. chinense also showed similar signals on ESR; iii) Powdered B. chinense also showed similar signals on g=2.005. Peroxidase activity, essential for producing polyphenolic substances, was detected in the cold water extract of B. chinense. In addition, the signal intensity of the ESR spectrum of B. chinense was increased after boiling. The data of the ESR spectra of the model reactions using lignin, arginine, proline and maltose also strongly suggested that a certain chemical modification proceeded during the hot water extraction to increase the percentage of the stable free radical. These facts strongly suggested that the mitogenic substance in B. chinense is a polyphenolic substance extracted by hot water, and the structure was modified during the extraction to increase the stable free radical components.
- 公益社団法人日本薬学会の論文
- 1997-01-15
著者
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OHNO Naohito
Laboratory far Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pha
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Ohno Naohito
東京薬科大学 免疫学
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Ohno Naohito
東京薬科大学 薬 微生物
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Ohno N
Laboratory For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm
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YADOMAE Toshiro
Laboratory for Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pha
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Ohno Naohito
Laboratory Of Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharma
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Ohno Naohito
Laboratory For Immunopharmacology Of Microbial Products Tokyo University Of Pharmacy And Life Scienc
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IZUMI Shigeru
Laboratory of Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Phar
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OHTSU Sadanori
Laboratory of Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Phar
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IWANAGA Shogo
Laboratory of Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Phar
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Ohno N
Laboratory Of Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharma
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Izumi S
Laboratory Of Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharma
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Izumi Shigeru
Laboratory Of Immunopharmacology Of Microbial Products Tokyo University Of Pharmacy And Life Science
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Iwanaga Shogo
Laboratory Of Immunopharmacology Of Microbial Products Tokyo University Of Pharmacy And Life Science
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Ohtsu S
Laboratory Of Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharma
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Yadomae T
Laboratory For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm
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