EFFECT OF A POLYSACCHARIDE FRACTION FROM GRIFOLA FRONDOSA ON IMMUNE RESPONSE IN MICE

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概要

• 論文の詳細を見る

• The biological and immunomodulating activities of polysaccharide fraction (GF-1), an antitumor poysaccharide fraction from cultured fruiting bodies of Grifola frondosa, was examined in mic. GF-1 showed no cytocidal effect on culturing tumor cells. However, GF-1 induced resistance against Sarcoma 180 in ICR mice which had completely regressed from the tumor by the effect of GF-1. The administration fo GF-1 into mice increased the weights or cell numbers of spleen, and peritoneal cavity. GF-1 enhanced the antigen specific antibody response and carbon cleatrance activity, whereas GF-1 did not show polyclonal B cell activation and mitogenic activities, and the effect on delayed type hypersensitivity.

• 社団法人日本薬学会の論文

著者

• OHNO NAOHITO

  Tokyo College of Pharmacy

• Ohno N

  Laboratory For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm

• YADOMAE Toshiro

  Tokyo University of Pharmacy and Life Science, School of Pharmacy

• SUZUKI IWAO

  Tokyo College of Pharmacy

• OIKAWA SHOZO

  Nippon Beet Sugar Mfg., Co. Ltd.

• SATO KICHIRO

  Nippon Beet Sugar Mfg., Co. Ltd.

• ITANI TERU

  Tokyo College of Pharmacy

• MIYAMZAKI TOSHIO

  Tokyo College of Pharmacy

• Ohno Naohito

  Laboratory For Immunopharmacology Of Microbial Products Tokyo University Of Pharmacy And Life Scienc

• Oikawa S

  Nippon Beet Sugar Mfg. Co. Ltd. Tokyo Jpn

• Sato K

  Toyama Medical And Pharmaceutical Univ. Toyama Jpn

• Miyazaki T

  Department Of Applied Microbiology Nippon Roche Research Center

• Suzuki Iwao

  Faculty Of Pharmaceutical Sciences Tohoku University

• Yadomae T

  Laboratory For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm

• Yadomae Toshiro

  Tokyo College Of Pharmacy

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