Antitumor Activity and Chemical Modification of Polysaccharides from Niohshimeji Mushroom, Tricholma giganteum
スポンサーリンク
概要
- 論文の詳細を見る
Two chemical modification procedures, Smith degradation and formolysis processes, were used in an attempt to improve the antitumor activity of water-soluble and water-insoluble polysaccharides prepared from the fruiting body of niohshimeji, Tricholoma giganteum. The chemically modified products were examined for their antitumor effects on Sarcoma 180 solid tumor implanted in mice. The following results were as follows: Some Smith degradation products, i.e., O-R-Flo-c-βP and O-R-FA-2 prepared from water-soluble polysaccharides, and O-R-FII-1 and O-R-FIII-2-c from water-insoluble polysaccharides, had higher antitumor activities than the original polysaccharides. None of the formolysis products, F-Flo-a, F-W-Flo-a, F-FA-3, F-W-FA-3 from water-soluble polysaccharides, and F-FII-2, F-W-FII-2, F-FIII-2-b, and F-W-FIII-2-b prepared from water-insoluble polysaccharides had improved antitumor activities.
- 社団法人日本農芸化学会の論文
- 1996-01-23
著者
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ITO Hitoshi
Department of Radiology, Okitama Public General Hospital
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Ma Yan
Faculty Of Basic Medical Science Norman Bethune University Of Medical Science
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Ma Y
Univ. Southern California Ca Usa
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Mayuzumi Yoshikazu
Myogi Mushroom Development
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Kakuda Takami
Department Of Legal Medicine Nihon University School Of Medicine
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Ito H
National Agricultural Res. Organization Mie Jpn
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Kakuda Takami
Central Research Lnstitute Lto-en Ltd.
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KINOSHITA TETSUYA
Department of Orthopaedic Surgery, Shinshu University School of Medicine
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MIZUNO Takashi
Department of Bioresource Science, Faculty of Agriculture, Tottori University
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Mayuzumi Yoshikazu
Myogi Mushroom Development Farm
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Ito Hiroyuki
Precision And Intelligence Laboratory Tokyo Institute Of Technology
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Ma Y
Departments Of Materials Science And Mechanical Engineering University Of Southern California
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Zhuang Cun
The United Graduate School Of Agricultural Sciences (shizuoka University) Gifu University
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Itoh H
Osaka Univ. Pharmaceutical Sci. Osaka Jpn
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Ito Hitoshi
The Japan Atomic Energy Research Institute Takasaki Radiation Establishment
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YEOHLUI Poohong
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University
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Ito H
Precision And Intelligence Laboratory Tokyo Institute Of Technology
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Kinoshita Tetsuya
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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Yeohlui Poohong
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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Mizuno Takashi
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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Mizuno Takashi
Department Of Agricultural Chemistry Shizuoka University
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Ito Hitoshi
Department Of Pharmacology Mie University School Of Medicine
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Mizuno Takashi
Department Of Agricultural Chemistry Faculty Of Agriculture Shizuoka University
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ITO Hitoshi
Department of Chemistry, College of Science and Engineering, Aoyama Gakuin University
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