Antitumor Activity of Some Polysaccharides Isolated from a Chinese Mushroom, "Huangmo", the Fruiting Body of Hohenbuehelia serotina(Biological Chemistry)

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概要

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• Polysaccharides were extracted from a Chinese mushroom, "Huangmo" with hot water (FI), 1% ammonium oxalate solution (FII), and 5% sodium hydroxide (FIII) and 20 more polysaccharides were isolated by ethanol precipitation, ion-exchange chromatography, gel filtration, and affinity chromatography. Of the six polysaccharides obtained, FI_0, FA-1, FA-2, FII-2, FIII-1-b, and FIII-2-b were selected on the basis of the results of the antitumor activity test (the Sarcoma 180/mice, i.p. method). Six fractions which showed relatively high activities were examined: FI_0, a mixture of galactose-containing heteroglycan and β-D-glucan; FA-1 and -2, β-D-glucan with galactose-containing hetero-glycan and protein; FII-2, β-D-glucan; and FIII-1-b and FIII-2-b, (1→6)-β-D-glucosyl branched (1→3)-β-D-glucan.

• 社団法人日本農芸化学会の論文
• 1991-11-23

著者

• Ma Yan

  Faculty Of Basic Medical Science Norman Bethune University Of Medical Science

• Ma Y

  Univ. Southern California Ca Usa

• Mizuno Takashi

  Faculty of Agriculture, Shizuoka University

• Ito Hitoshi

  School of Medicine, Mie University

• Ito H

  National Agricultural Res. Organization Mie Jpn

• Mayuzumi Yoshikazu

  Myogi Mushroom Development Farm

• Ito Hiroyuki

  Precision And Intelligence Laboratory Tokyo Institute Of Technology

• Ma Y

  Departments Of Materials Science And Mechanical Engineering University Of Southern California

• Ito Hitoshi

  The Japan Atomic Energy Research Institute Takasaki Radiation Establishment

• Ito H

  Precision And Intelligence Laboratory Tokyo Institute Of Technology

• Mizuno Takashi

  Faculty Of Agriculture Shizuoka University

• Ito Hitoshi

  School Of Medicine Mie University

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