Antitumor Active Fucoidan from the Brown Seaweed, Umitoranoo (Sargassum thunbergii)
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概要
- 論文の詳細を見る
Neutral and acidic polysaccharides and their protein complexes were fractionated and purified from the brown seaweed umitoranoo (Sargassum thunbergii) by fractional extraction, iron-exchange chromatography, and gel filtration. Thirty-one polysaccharide fractions were obtained and tested for antitumor activity in mice with Ehrlich carcinoma transplanted i.p. Two of the fractions, GIV-A ([α]^<25>_D -127° and mol. wt., 19,000) and GIV-B ([α]^<25>_D -110° and mol. wt., 13,500) had such activity. On the basis of chemical and spectral analyses, these compounds were found to be a fucoidan or L-fucan containing approx. 30% sulfate ester groups per fucose residue, about 10% uronic acid, and less than 2% protein
- 社団法人日本農芸化学会の論文
- 1995-04-23
著者
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ITO Hitoshi
Department of Radiology, Okitama Public General Hospital
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Ito H
National Agricultural Res. Organization Mie Jpn
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MIZUNO Takashi
Department of Bioresource Science, Faculty of Agriculture, Tottori University
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Ito Hiroyuki
Precision And Intelligence Laboratory Tokyo Institute Of Technology
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Zhuang Cun
The United Graduate School Of Agricultural Sciences (shizuoka University) Gifu University
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Itoh H
Osaka Univ. Pharmaceutical Sci. Osaka Jpn
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Ito Hitoshi
The Japan Atomic Energy Research Institute Takasaki Radiation Establishment
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Zhuang Cun
United Graduate School of Agricultural Sciences,Gifu University(Shizuoka University)
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Ito H
Precision And Intelligence Laboratory Tokyo Institute Of Technology
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Itoh Hiroko
Laboratory of Marine Biochemistry, Faculty of Bioresources, Mie University
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Mizuno Takashi
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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Mizuno Takashi
Department Of Agricultural Chemistry Shizuoka University
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Ito Hitoshi
Department Of Pharmacology Mie University School Of Medicine
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Mizuno Takashi
Department Of Agricultural Chemistry Faculty Of Agriculture Shizuoka University
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ITO Hitoshi
Department of Chemistry, College of Science and Engineering, Aoyama Gakuin University
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