Reduction Effect of Theanine on Blood Pressure and Brain 5-Hydroxyindoles in Spontaneously Hypertensive Rats
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概要
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The effect of theanine, one of the components of green tea, on the blood pressure and brain 5-hy-droxyindoles in spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY) was investigated by intraperitoneally administering theanine. The effect of glutamine, which is structurally similar to theanine, was also examined. When SHR were injected with various amounts of theanine (0, 500, 1000, 1500, and 2000mg/kg), the change was dose-dependent, and a significant decrease in blood pressure was observed with the high doses (1500 and 2000 mg/kg). A dose of 2000 mg/kg of theanine did not alter the blood pressure of WKY, while the same dose to SHR decreased it significantly. On the other hand, glutamine administration to SHR did not change either the blood pressure or the heart rate. The brain 5-hydroxyindole level was significantly decreased by theanine administration to both WKY and SHR, the decrease being dose-dependent.
- 社団法人日本農芸化学会の論文
- 1995-04-23
著者
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SAGESAKA Yuko
Central Research Institute, ITO EN, LTD.
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Sagesaka Yuko
Central Research Institute Ito En Ltd.
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KAKUDA Takami
Central Research Institute, Ito En, Ltd.
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Kakuda Takami
Department Of Legal Medicine Nihon University School Of Medicine
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Kato Y
Tokaigakuen Women's College
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Sagesaka Yuko
Central Research Lnstitute Lto-en Ltd.
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Kakuda Takami
Central Research Lnstitute Lto-en Ltd.
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Kakuda Takami
Central Research Institute Itoen Ltd.
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YOKOGOSHI Hidehiko
School of Food and Nutritional Sciences and COE Program in the 21st Century, University of Shizuoka
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Yokogoshi Hidehiko
School Of Food And Nutritional Sciences And Coe Program In The 21st Century The University Of Shizuo
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Kato Yukiko
School Of Food And Nutritional Sciences University Of Shizuoka
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Takihara-Matsuura Takanobu
Central Research lnstitute, lto-en Ltd.
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Takeuchi Naokazu
Nagoya Research and Development Center, Mitsubishi Heavy lndustries Ltd.
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Takihara-matsuura Takanobu
Central Research Lnstitute Lto-en Ltd.
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Kinoshita Tetsuya
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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Takeuchi Naokazu
Nagoya Research And Development Center Mitsubishi Heavy Lndustries Ltd.
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Kakuda Takami
Central Research Institute Ito En Ltd.
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SAGESAKA Yuko
Central Research Institute
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KAKUDA Takami
Central Research Institute
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