Improving Effect of Dietary Taurine on Marked Hypercholesterolemia Induced by a High-cholesterol Diet in Streptozotocin-induced Diabetic Rats
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概要
- 論文の詳細を見る
The effect of dietary taurine on hypercholesterolemia induced by a high-cholesterol diet in streptozotocin (STZ)-induced diabetic rats was investigated. The concentrations of serum and liver cholesterol were markedly elevated in STZ-diabetic rats fed on the cholesterol-containing diet, and dietary taurine significantly reduced this elevated level of cholesterol in the serum and liver. The gene expression of cholesterol 7α-hydroxylase (CYP7A1), which is the ratelimiting enzyme for cholesterol degradation, was induced by the supplementation of taurine to the high-cholesterol diet. It is suggested that one of the reasons for this hypocholesterolemic action by taurine might have been the enhancement of cholesterol degradation.
- 社団法人日本農芸化学会の論文
- 1999-11-23
著者
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YOKOGOSHI Hidehiko
School of Food and Nutritional Sciences and COE Program in the 21st Century, University of Shizuoka
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Mochizuki Hideki
School Of Food And Nutritional Sciences The University Of Shizuoka
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Yokogoshi Hidehiko
Laboratory Of Nutritional Biochemistry School Of Food And Nutritional Sciences Coe Program In The 21
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Yokogoshi Hidehiko
Laboratories Of Nutritional Biochemistry School Of Food And Nutritional Sciences The University Of S
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Yokogoshi Hidehiko
Laboratory Of Nutritional Biochemistry School Of Food And Nutritional Sciences University Of Shizuok
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Yokogoshi Hidehiko
School Of Food And Nutritional Sciences And Coe Program In The 21st Century The University Of Shizuo
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ODA Hiroaki
Department of Applied Molecular Biosciences, Nagoya University
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Oda H
Nagoya Univ. Aichi Jpn
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Oda H
Department Of Applied Biological Sciences Nagoya University
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Yokogoshi H
Laboratory Of Nutritional Biochemistry School Of Food And Nutritional Sciences Coe Program In The 21
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TAKIDO Jun
School of Food and Nutritional Sciences, The University of Shizuoka
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Takido J
School Of Food And Nutritional Sciences The University Of Shizuoka
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Takido Jun
School Of Food And Nutritional Sciences The University Of Shizuoka
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Oda Hiroaki
Department Of Applied Biological Sciences Nagoya University
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Yokogoshi Hidehiko
Lab. Of Nutritional Biochemistry Univ. Of Shizuoka
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ODA Hiroaki
Department of Agricultural Chemistry, Nagoya University
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