Induction of Cytochrome P-450s and Expression of Liver-specific Genes in Rat Primary Hepatocytes Cultured on Different Extracellular Matrices
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概要
- 論文の詳細を見る
Freshly isolated hepatocytes were cultured on an EHS-gel prepared from EHS-tumor, poly-N-p-vinylbenzyl-D-lactonamide (PVLA), and type I collagen (TIC). Hepatocytes on EHS-gel showed a spherical shape and much more strongly maintained the inducible expression of cytochrome P-450 genes which were lost on PVLA and TIC. Further, the expression of liver-specific genes were maintained on EHS gel at the highest level, and then higher on PVLA than TIC.
- 社団法人日本農芸化学会の論文
- 1994-08-23
著者
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Yabe Aya
Department Of Molecular Biology Institute Of Gerontology Nippon Medical School
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Matsushita Natsuki
Laboratory Of Nutritional Biochemistry School Of Agricultural Sciences Nagoya University
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YOSHIDA Akira
Laboratory of Nutritional Biochemistry, Department of Agricultural Chemistry, School of Agriculture,
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Yoshida Akira
First Department Of Internal Medicine University Of Fukui
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赤池 敏宏
東京工業大学 大学院生命理工学研究科生体分子機能工学専攻
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Oda H
Nagoya Univ. Aichi Jpn
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Oda H
Department Of Applied Biological Sciences Nagoya University
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Oda Hiroaki
Laboratory Of Nutritional Biochemistry Department Of Agricultural Chemistry Nagoya University
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Akaike Toshihiro
Faculty Of Bioscience And Biotechnology Tokyo Institute Of Technology
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Oda Hiroaki
Department Of Applied Biological Sciences Nagoya University
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Kosayashi Kazukiyo
Laboratory of Polymer Chemistry, School of Agricultural Sciences, Nagoya, Nagoya University
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Yoshida Akira
Laboratory Of Nutritional Biochemistry Department Of Agricultural Chemistry Nagoya University
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Kosayashi Kazukiyo
Laboratory Of Polymer Chemistry School Of Agricultural Sciences Nagoya Nagoya University
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