Effect of a Thyroid Hormone Treatment on Brain Protein Synthesis in Rats
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概要
- 論文の詳細を見る
The effect of the thyroid hormone on the rate of brain protein synthesis in rats was studied. Experiments were conducted on three groups of rats given 6-propyl-2-thiouracil (PTU, a thyroid inhibitor) without a triiodothyronine (T_3) treatment, those treated with PTU + T_3, and those treated with neither PTU nor T_3 (control). The fractional rates of protein synthesis in the brain, liver, and kidney of rats given PTU + T_3 were significantly greater than those in rats given PTU alone. In the brain and kidney, the RNA activity [g of protein synthesized/(g of RNA.d)] were significantly correlated with the fractional rates of protein synthesis. In the liver and kidney, the RNA concentration (mg of RNA/g of protein) was related to the fractional rate of protein synthesis. These results suggest that the thyroid hormone treatment would be likely to increase the rate of protein synthesis in the brain of rats, and that the RNA activity is, at least partly, related to the fractional rate of brain protein synthesis.
- 社団法人日本農芸化学会の論文
- 1997-09-23
著者
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YOKOGOSHI Hidehiko
Laboratory of Nutritional Biochemistry, Global COE Program in the 21st Century, Graduate School of N
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Yabe Aya
Department Of Molecular Biology Institute Of Gerontology Nippon Medical School
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HAYASE Kazutoshi
Department of Home Economics, Aichi University of Education
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YOSHIDA AKIRA
Department of Radiological Sciences, Hiroshima Prefectural College of Health Science
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MORIYAMA Michie
Department of Home Economics, Aichi Gakusen University
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Moriyama Michie
Department Of Home Economics Aichi Gakusen College
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Hayase Kazutoshi
Department Of Home Economics Aichi University Of Education
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Yokogoshi Hidehiko
Laboratory Of Nutritional Biochemistry School Of Food And Nutritional Sciences Coe Program In The 21
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Yokogoshi Hidehiko
Laboratories Of Nutritional Biochemistry School Of Food And Nutritional Sciences The University Of S
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Yokogoshi Hidehiko
Laboratory Of Nutritional Biochemistry School Of Food And Nutritional Sciences University Of Shizuok
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Yoshida Akira
First Department Of Internal Medicine University Of Fukui
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Yokogoshi H
Laboratory Of Nutritional Biochemistry School Of Food And Nutritional Sciences Coe Program In The 21
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NAGANUMA Yaeko
Department of Home Economics, Aichi University of Education
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Naganuma Yaeko
Deparmtent Of Home Economics Aichi University Of Education
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Hayase K
Department Of Home Economics Aichi University Of Education
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Yoshida Akira
Department Of Cardiology Mitsubishi Kyoto Hospital
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Yokogoshi Hidehiko
Lab. Of Nutritional Biochemistry Univ. Of Shizuoka
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Yoshida Akira
Department Of Cardiology Kyoto National Hospital
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Yoshida Akira
Department Of Agricultural Chemistry Nagoya University
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