Effects of Dietary Fructose, Glucose, Fibers and Hypolipidemic Drugs on Serum and Liver Lipids in Rats(Food & Nutrition)
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概要
- 論文の詳細を見る
To investigate the effects of dietary glucose and fructose on serum lipids, rats of four strains (Donryu, Sprague-Dawley, Fischer and Wistar) were fed a diet containing either glucose or fructose, Fructose feeding to all rats weighing about 140 g of the four strains resulted in significant increases in serum cholesterol and triglyceride. Of the Donryu rats with initial body weights of 65 g, 179 g and 463 g, serum cholesterol increased in those weighing 179 g when fed a fructose diet. Whereas, fructose feeding resulted in significant increases in serum triglyceride in those weighing about 179 g and 463 g. Therefore, in the following experiments, rats of the Donryu strain weighing about 120〜160 g were used. The hypercholesterolemia induced on feeding a fructose diet to the Donryu rats was prevented by the addition of corn oil, konjac mannan, pectin, guar gum, cholestyramine and clofibrate. Both cholestyramine and phthalate were effective, respectively, in preventing the increase in serum triglyceride. Fructose caused a slight increase in or showed an increasing tendency as to the liver lipid content, and a slight reduction in or a decreasing tendency as to the liver cholesterol level as compared to in the case of glucose except for a few results. The addition of fibers and hypolipidemic drugs had no effects on the liver lipids. The overall results indicate that the effects of fibers and hypolipidemic drugs on serum cholesterol in rats fed a fructose diet are similar to those reported previously for rats fed either a cholesterol-diet or a histidine-excess diet.
- 社団法人日本農芸化学会の論文
- 1987-03-22
著者
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AOYAMA Yoritaka
Laboratory of Food Biochemistry, Division of Applied Bioscience, Graduate School of Agriculture, Hok
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YOSHIDA Akira
Laboratory of Nutritional Biochemistry, Department of Agricultural Chemistry, School of Agriculture,
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Yoshino Koji
Laboratory Of Nutritional Biochemistry Department Of Agricultural Chemistry School Of Agriculture Na
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Ashida K
National Research Inst. Fisheries Science Ministry Of Agriculture Forestry And Fisheries Tokyo Jpn
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OTAKI Ruri
Laboratory of Nutritional Biochemistry, Department of Agricultural Chemistry, School of Agriculture,
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ASHIDA Kiyoshi
Laboratory of Nutritional Biochemistry, Department of Agricultural Chemistry, School of Agriculture,
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Otaki Ruri
Laboratory Of Nutritional Biochemistry Department Of Agricultural Chemistry School Of Agriculture Na
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Ashida Kiyoshi
Laboratory Of Nutritional Biochemistry Department Of Agricultural Chemistry School Of Agriculture Na
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Aoyama Yoritaka
Laboratory Of Nutritional Biochemistry Department Of Agricultural Chemistry School Of Agriculture Na
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Aoyama Yoritaka
Laboratory Of Food Biochemistry Division Of Applied Bioscience Graduate School Of Agriculture Hokkai
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Aoyama Yoritaka
Laboratory Of Food Biochemistry Department Of Bioscience And Chemistry Faculty Of Agriculture Hokkai
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Yoshida Akira
Laboratory Of Nutritional Biochemistry Department Of Agricultural Chemistry Nagoya University
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Yoshida Akira
Laboratory Of Nutritional Biochemistry Department Of Agricultural Chemistry School Of Agriculture Na
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