Different Responses of Apolipoprotein A-I, A-IV, and B Gene Expression during Intestinal Adaptation to a Massive Small Bowel Resection in Rats
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概要
- 論文の詳細を見る
Gene expression of apolipoproteins (apo) A-I, A-IV, and B, the predominant protein components of chylomicrons, was investigated in the residual ileum after a massive small bowel resection in rats. A Northern blot analysis showed that the apo A-IV mRNA level, but not the apo A-I and B mRNA levels, in the ileum was significantly higher in the resected rats than in the sham-operated rats 24 h and 2 wk post-surgery. RT-PCR coupled with a primer extension assay revealed that the apo B-48 mRNA/apo B-100 mRNA ratio, i.e., apo B mRNA editing, in the ielum was unchanged by the resection. It is thus concluded that, among the major intestinal apolipoproteins, apo A-IV is the only one whose gene expression is influenced by loss of the proximal intestine.
- 社団法人日本農芸化学会の論文
- 1997-11-23
著者
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Sonoyama Kei
Laboratory Of Food Biochemistry Division Of Applied Bioscience Graduate School Of Agriculture Hokkai
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Sonoyama Kei
Laboratory Of Food Biochemistry Department Of Bioscience And Chemistry Faculty Of Agriculture Hokkai
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AOYAMA Yoritaka
Laboratory of Food Biochemistry, Division of Applied Bioscience, Graduate School of Agriculture, Hok
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Aoyama Yoritaka
Laboratory Of Food Biochemistry Department Of Bioscience And Chemistry Faculty Of Agriculture Hokkai
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