Inhibiting Effects of Theanine on Caffeine Stimulation Evaluated by EEG in the Rat
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概要
- 論文の詳細を見る
In this study, the inhibiting action of theanine on the excitation by caffeine at the concentration regularly associated with drinking tea was investigated using electroencephalography (EEG) in rats. First, the stimulatory action by caffeine i.v. administration at a level higher than 5μmol/kg (0.970 mg/kg) b.w. was shown by means of brain wave analysis, and this level was suggested as the minimum dose of caffeine as a stimulant. Next, the stimulatory effects of caffeine were inhibited by an i.v. administration of theanine at a level higher than 5μmol/kg (0.781 mg/kg) b.w., and the results suggested that theanine has an antagonistic effect on caffeine's stimulatory action at an almost equivalent molar concentration. On the other hand, the excitatory effects were shown in the rat i.v. administered 1 and 2 μmol/kg (0.174 and 0.348 mg/kg) b.w. of theanine alone. These results suggested two effects of theanine, depending on its concentration.
- 社団法人日本農芸化学会の論文
- 2000-02-23
著者
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KAKUDA Takami
Central Research Institute, Ito En, Ltd.
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UNNO Tomonori
Central Research Institute, Itoen Ltd.
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Nozawa Ayumu
Central Research Institute, ITOEN, Ltd.
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Unno T
Department Of Home Economics Tokyo Kasei Gakuin University
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Unno Tomonori
Central Research Institute Ito En Ltd.
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Okai Osamu
Department of Clinical Physiology, School of Health Science, Kyorin University
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Okamura Noritaka
Department of Clinical Physiology, School of Health Science, Kyorin University
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Kakuda T
Central Research Institute Ito En Ltd.
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Kakuda Takami
Central Research Institute Itoen Ltd.
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Okai O
Department Of Physiology School Of Health Science Kyorin University
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Okai Osamu
Department Of Clinical Physiology School Of Health Science Kyorin University
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Nozawa Ayumu
Central Research Institute Ito En Ltd.
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Nozawa A
Research And Education Center For Genetic Information Nara Institute Of Science And Technology:(pres
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Okamura Noritaka
Department Of Clinical Physiology School Of Health Science Kyorin University
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Okamura Noritaka
Department Of Medical Laboratory Ehime College Of Health Science
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Kakuda Takami
Central Research Institute Ito En Ltd.
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UNNO Tomonori
Central Research Institute
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NOZAWA Ayumu
Central Research Institute
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KAKUDA Takami
Central Research Institute
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