SAF, a New Cell Aggregation Factor Produced by Streptomyces murinus Strain No. A-2805(Biological Chemistry)

スポンサーリンク

概要

• 論文の詳細を見る

• We searched for a new cell aggregation factor, and found one we called SAF in the mycelia of a strain of Streptomyces murinus. SAF was purified by active carbon and ion exchange column chromatographies and gel filtration of Sepharose 2B from the homogenized mycelia by sonication. SAF was stable from pH 7 to 9 at 37℃, and up to 40℃ at pH 8.0. The aggregation activity of SAF was maximum around pH8.0 at 30℃, and the factor required for its activity metallic ions such as calcium and manganese. The aggregation activity of SAF was inhibited by laminarin, but it was not influenced by various other saccharides. SAF aggregated E. coli, S. aureus, M. luteus, sarcoma 180, and HeLa cells as well as S. marcescens, above all, its highest activity was toward B. subtilis, but P. vulgaris, P, aeruginosa, C. albicans, each type of human erythrocytes, and hepatoma 109A cells were quite resistant to SAF. These properties has proved that SAF is completely different from the other aggregation factors so far reported.

• 社団法人日本農芸化学会の論文
• 1987-11-23

著者

• Yokomizo Kazumi

  Laboratory of Presymptomatic Medical Pharmacology, Faculty of Pharmaceutical Sciences, Sojo Universi

• UYEDA Masaru

  Laboratory of Pharmaceutical Microbiology, Faculty of Medical and Pharmaceutical Sciences, Kumamoto

• Uyeda M

  Kumamoto Univ. Kumamoto Jpn

• Uyeda Masaru

  Shokei University

• Yokomizo K

  Kumamoto Univ. Kumamoto Jpn

• Yokomizo Kazumi

  Laboratory Of Pharmaceutical Microbiology Faculty Of Medical And Pharmaceutical Sciences Kumamoto Un

• Yokomizo Kazumi

  Faculty Of Pharmaceutical Sciences Kumamoto University

• Uyeda Masaru

  Laboratory Of Medicinal Microbiology Faculty Of Pharmaceutical Sciences Kumamoto University

• SHIBATA Motoo

  Laboratory of Medicinal Microbiology, Faculty of Pharmaceutical Sciences, Kumamoto University

• SUZUKI KEITAROU

  Laboratory of Medicinal Microbiology, Faculty of Pharmaceutical Sciences Kumamoto University

• SHIBATA Motoo

  Faculty of Pharmaceutical Sciences, Kumamoto University

• Suzuki Keitarou

  Laboratory Of Medicinal Microbiology Faculty Of Pharmaceutical Sciences Kumamoto University

• Suzuki K

  Department Of Nutritional Science Tokyo University Of Agriculture

• Udayama Manabu

  Faculty Of Pharmaceutical Sciences Kumamoto University

• KOSAI Mika

  Laboratory of Medicinal Microbiology, Faculty of Pharmaceutical Sciences, Kumamoto University

• Uyeda Masaru

  Department Of Pharmaceutical Microbiology Faculty Of Medical And Pharmaceutical Sciences Kumamoto Un

• Kido Y

  Div. Of Instrumental Analysis Inst. Of Resource Dev. And Analysis Kumamoto Univ.

• Shibata Motoo

  Laboratory Of Medicinal Microbiology Faculty Of Pharmaceutical Sciences Kumamoto University

• Kosai Mika

  Laboratory Of Medicinal Microbiology Faculty Of Pharmaceutical Sciences Kumamoto University

• Suzuki Kazuharu

  Department Of Nutritional Science Faculty Of Applied Bioscience Tokyo University Of Agriculture

関連論文

• Glycyrrhizin Attenuates Mucus Production by Inhibition of MUC5AC mRNA Expression In Vivo and In Vitro
• Hesperidin, a citrus flavonoid, inhibits bone loss and decreases serum and hepatic lipids in ovariectomized mice.
• Structures of Three New Oleanene Glucuronides Isolated from Lathyrus palustris var. pilosus and Hepatoprotective Activity
• A New Oleanene Glucuronide Having a Branched-Chain Sugar from Melilotus officinalis
• Anti-herpes Virus Type 1 Activity of Oleanane-Type Triterpenoids(Pharmacognosy)
• A New Lignan Glycoside and Phenylethanoid Glycosides from Strobilanthes cusia BREMEK
• Two Novel Antioxidant Ortho-Benzoyloxyphenyl Acetic Acid Derivatives from the Fruit of Vaccinium uliginosum
• Absence of Negative Feedback on Intestinal Magnesium Absorption on Excessive Magnesium Administration in Rats
• Dietary Iron Deficiency Decreases Serum Osteocalcin Concentration and Bone Mineral Density in Rats
• Effects of Lowering Food Intake by High Phosphorus Diet on Parathyroid Hormone Actions and Kidney Mineral Concentration in Rats
• Reduction in Dietary Calcium/Phosphorus Ratio Reduces Bone Mass and Strength in Ovariectomized Rats Enhancing Bone Turnover
• Effects of Dietary Phosphorus Intake on Bone Mineralization and Calcium Absorption in Adult Female Rats
• Decreased mRNA Expression of the PTH/PTHrP Receptor and Type II Sodium-Dependent Phosphate Transporter in the Kidney of Rats Fed a High Phosphorus Diet Accompanied with a Decrease in Serum Calcium Concentration
• Sex Differences in Kidney Mineral Concentrations and Urinary Albumin Excretion in Rats Given High-phosphorus Feed(Food & Nutrition Sience)
• Changes in N-Acetyl-β-D-Glucosaminidase Activity in the Urine and Urinary Albumin Excretion in Magnesium Deficient Rats(Food & Nutrition Science)
• Greater Effect of Dietary Potassium Tripolyphosphate than of Potassium Dihydrogenphosphate on the Nephrocalcinosis and Proximal Tubular Function in Female Rats from the Intake of a High-phosphorus Diet
• High P Diet Induces Acute Secretion of Parathyroidhormone without Alteration of Serum Calcium Levels in Rats
• Comparison of Various Phosphate Salts as the Dietary Phosphorus Source on Nephrocalcinosis and Kidney Function in Rats
• Fattiviracin A1, a Novel Antiviral Agent Produced by Streptomyces microflavus Strain No. 2445 II. Biological Properties
• Fattiviracin A1, a Novel Antiherpetic Agent Produced by Streptomyces microflavus Strain No. 2445 I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Structure Elucidation
• Coexpression of the CUG-Binding Protein Reduces DM Protein Kinase Expression in COS Cells
• Anti-herpes Virus Activity of Fabaceous Triterpenoidal Saponins
• Anti-herpes Virus Activity of Solanum Steroidal Glycosides
• Glycyrrhizin Inhibits Interleukin-8 Production and Nuclear Factor-κB Activity in Lung Epithelial Cells, but Not Through Glucocorticoid Receptors
• A New Antiherpetic Agent, AH-1763 IIa, Produced by Streptomyces cyaneus Strain No. 1763
• A New Antiherpetic Agent Produced by Streptomyces sp.Strain No.758
• Structures of Fattiviracin Family, Antiviral Antibiotics
• Effect of Validamycin on β-d-Glucan-degrading Enzymes from Rhizoctonia solani
• Partial Hydrolysis of Soyasaponin I and the Hepatoprotective Effects of the Hydrolytic Products. Study of the Structure-Hepatoprotective Relationship of Soyasapogenol B Analogs
• Preventive Effects of Saponins from Puerariae Radix (the root of Pueraria lobata OHWI) on in Vitro Immunological Injury of Rat Primary Hepatocyte Cultures
• Enhanced Production of Fattiviracins by Bacitracin-resistant Strains of Streptomyces microflavus Strain No. 2445
• Inhibitory Activities of(-)-Epigallocatechin-3-O-gallate against Topoisomerases I and II
• Topostatin, a Novel Inhibitor of Topoisomerases I and II Produced by Thermomonospora alba Strain No. 1520 III. Inhibitory Properties
• Topostatin, a Novel Inhibitor of Topoisomerases I and II Produced by Thermomonospora alba Strain No. 1520 II. Physico-chemical Properties and Structure Elucidation
• Topostatin, a Novel Inhibitor of Topoisomerases I and II Produced by Thermomonospora alba Strain No. 1520 I. Taxonomy, Fermentation, Isolation and Biological Activities
• Formation of a Chlorhexidine Degradation Intermediate through Pyruvate Incorporation by Pseudomonas sp.no.A-3
• CELL AGGREGATION FACTORS PRODUCED BY STREPTOMYCETES
• N-Long-chain Monoacylated Derivatives of 2,6-Diaminopyridine with Antiviral Activity
• Synthesis and Antiviral Activities of Some 4,4'- and 2,2'-Dihydroxytriphenylmethanes
• Synthesis and Antiviral Activities of Some 4,4'-Dihydroxytriphenylmethanes
• Synthesis of 2, 2'-Dihydroxybisphenols and Antiviral Activity of Some Bisphenol Derivatives
• Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the β-subunit of coatomer complex, β-COP
• Heterogeneous Nuclear Ribonucleoprotein K Interacts with and Is Proteolyzed by Calpain in vivo(Biochemistry & Molecular Biology)
• LysR-type Transcriptional Regulator ChiR Is Essential for Production of All Chitinases and a Chitin-Binding Protein, CBP21,in Serratia marcescens 2170
• Synthesis and Antiviral Activities of N-Mono- and/or N,N'-Di- Carbamoyl and Acyl Derivatives of Symmetrical Diamines
• N-Monocarbamoyl Derivatives of Symmetrical Diamines with Antiviral Activity
• Study of Structure-Hepatoprotective Relationships of Oleanene-Type Triterpenoidal Glucuronides Obtained from Several Fabaceous Plants on Rat Primary Hepatocyte Cultures
• Hepatoprotective and Hepatotoxic Actions of Oleanolic Acid-Type Triterpenoidal Glucuronides on Rat Primary Hepatocyte Cultures
• Pentalenolactone I and Hygromycin A, Immunosuppressants produced by Streptomyces filipinensis and Streptomyces hygroscopicus
• Biosynthesis of Fattiviracin FV-8,an Antiviral Agent
• Antiviral Activity of Fattiviracin FV-8 against Human Immunodeficiency Virus Type 1 (HIV-1)
• Effects of DNA on the Formation of Cell Aggregate by a Microbial Hepatoma Aggregation Factor (HAF)
• Effects of Proteases on Hepatoma AH109A Cells Aggregated by a Microbial Hepatoma Aggregation Factor (HAF)
• HAF, Hepatoma Aggregation Factor Produced by Streptomyces sp. Strain No. A-6143(Biological Chemistry)
• 3315-AF2, a Cell Aggregation Factor Produced by Streptomyces sp. Strain No.A-3315(Biological Chemistry)
• Effects of Validamycin on Glucan Synthesis by Cell-free Extracts from Rhizoctonia solani(Biological Chemistry)
• Cell Aggregation Factor Produced by Streptomyces sp. Strain No.A-3315(Biological Chemistry)
• Characteristics and Action Mechanism of SAF, Cell Aggregation Factor Produced by Streptomyces murinus Strain No.A-2805(Biological Chemistry)
• SAF, a New Cell Aggregation Factor Produced by Streptomyces murinus Strain No. A-2805(Biological Chemistry)
• Characterization of B-1625 FA_, an Acidic Actinomycin Congener(Microbiology & Fermentation Industry)
• Morphological Mutant of Rhizoctonia solani and Its Cell Wall Component
• Serratia marcescens-Lytic Enzyme Produced by Micromonospor sp. Strain No. 152
• Partial Amino Acid Sequence of an Alkaline Protease Inhibitor, API-2 (b and c)
• MICROBIAL DEGRADATION OF DISINFECTANTS-ON THE DEGRADATION PATHWAYS OF CHLORHEXIDINE
• MICROBIAL DEGRADATION OF DISINFECTANTS MICROBIAL DEGRADATION OF CHLORHEXIDINE AND ITS DEGRADATION PATHWAY
• Microbial Degradation of Disinfectants. X Microbial Degradation of Chlorhexidine and Its Degradation Products (Proceedings of the 14th Symposium on Environmental Pollutants and Toxicology)
• Change in a Cell-Wall Component of Rhizoctonia solani Inhibited by Validamycin(Microbiology & Fermentation Industry)
• Chitinases A, B, and C1 of Serratia marcescens 2170 Produced by Recombinant Escherichia coli : Enzymatic Properties and Synergism on Chitin Degradation(Biochemistry & Molecular Biology)
• Hepatoprotective and Hepatotoxic Activities of Sophoradiol Analogs on Rat Primary Liver Cell Cultures
• High Phosphorus Diet Changes Phosphorus Metabolism Regardless of PTH Action in Rats
• An Inhibitor of S-Hemolysin, SHI, Produced by Streptomyces sp. Strain No. 6288
• Purification and Some Properties of S-Hemolysin Produced by Streptomyces sp. Strain No. A-6288
• Hyphal Extension Inhibitors I and II with Similar Inhibitory Spectra to Validamycin, Isolated from Hyphae of Rhizoctonia solani(Microbiology & Fermentation Industry)
• HPLC Profile Analysis of Oleanene-Glucuronides in Several Edible Beans
• Dissociation of m-Calpain Subunits Occurs after Autolysis of the N-Terminus of the Catalytic Subunit, and Is Not Required for Activation
• Limited Proteolysis of Filamin Is Catalyzed by Caspase-3 in U937 and Jurkat Cells^1
• SYNTHESIS OF 6-PHENYL ANALOGS OF TOXOFLAVIN AND THEIR 4-OXIDES AND ANTIMICROBIAL ACTIVITIES OF TOXOFLAVIN AND ITS ANALOGS
• Microbial Degradation of Disinfectants : Two New Aromatic Degradation Products of Chlorhexidine, Chlorhexidine Aromatic Degradation Product (CHADP)-4 and CHADP-6, Produced by Pseudomonas sp. Strain No. A-3
• Acrinol Degradation Products (ANDP)-8, A Novel Acrinol Degradation Product by Light
• Inhibitory Properties of Antitumor Prostaglandins against Topoisomerases(Biochemistry & Molecular Biology)
• Inhibition of Topoisomerases by Antitumor Prostaglandins.
• A Hemolysin Produced by Streptomyces sp. Strain No. A-6288(Biological Chemistry)
• Microbial Degradation of Disinfectants. A New Chlorhexidine Degradation Intermediate (CHDI), CHDI-C, Produced by Pseudomonas sp. Strain No. A-3
• ANDP-2, A Novel Acrinol Degradation Product by Light
• Complete Degradation of the Endocrine-Disrupting Chemical Dimethyl Phthalate ester by Flavobacterium sp.
• Complete Degradation of the Endocrine-Disrupting Chemical Phthalic Acid by Flavobacterium sp.
• ANDP-7, a Novel Acrinol Degradation Product by Light
• Potential Cosmetic Whitening Agents from Insect Cuticle : Tyrosinase Inhibitory Activity of N-Acetyldopamine Dimers from Exuviae of Cicada, Cryptotympana tustulata F_
• Hypoglycemic and Hypolipidemic Effects of Hesperidin and Cyclodextrin-Clathrated Hesperetin in Goto-Kakizaki Rats with Type 2 Diabetes
• Glycyrrhizin Attenuates Mucus Production by Inhibition of MUC5AC mRNA Expression In Vivo and In Vitro
• Glycyrrhizin Inhibits IL-8 Production and NF-κB Activity in Lung Epithelial Cells, But Not Through Glucocorticoid Receptors
• Hepatoprotective Effects of Oleanene Glucuronides in Several Edible Beans
• HPLC Profile Analysis of Hepatoprotective Oleanene-Glucuronides in Several Soybean Processed Foods
• Membrane-bound Dehydrogenase from Serratia marcescens That Catalyzes Oxidation of Maltose
• Production of Acidic Actinomycin Congeners by a Mutant Strain of Streptomyces antibioticus, No. B-1625
• M-GCI, a Novel β-Glucuronidase Inhibitor Produced by Micromonospora sp. Strain No. BR-1613
• Purification and Properties of Lipase Activator Produced by Streptomyces sp. Strain No. BR-1381
• Serratia-lytic Enzyme Produced by Streptomyces sp. Strain No. 177
• Action of Lipase Activator (LAV) Produced by Streptomyces sp. Strain No. BR-1381 on Phycomyces nitens Lipase
• Selectively Increased Production of Acidic Actinomycin Congener, B-1625 FA2β, on Combined Use of Sarcosine and Ferrous Sulfate

もっと見る 閉じる

スポンサーリンク