Cell Aggregation Factor Produced by Streptomyces sp. Strain No.A-3315(Biological Chemistry)

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概要

• 論文の詳細を見る

• We searched for a new aggregation factor, and found one we named 3315-AF in the culture filtrate of Streptomyces sp. strain No. A-3315. 3315-AF was purified by active carbon treatment, ethanol precipitation, gel filtration on Sepharose 2B, ether extraction, silica gel chromatography and gel filtration on Sephadex LH-20. 3315-AF was found to be a triglyceride which consists of myristic acid, pentadecanoic acid, and palmitic acid. The aggregation activity of 3315-AF was maximum around pH 8.0 at 30℃ and the activity increased by addition of metallic ions such as calcium and cobalt. Hyaluronic acid, ovalbumin, BSA, and casein inhibited the aggregation activity. 3315-AF aggregated Proteus vulgaris and HeLa cells as well as Serratia marcescens and weakly aggregated Saccharomyces cerevisiae, Candida albicans, C. neoformans, and Leukemia P338, but it was inert to human erythrocytes and Sarcoma 180.

• 社団法人日本農芸化学会の論文
• 1988-10-23

著者

• UYEDA Masaru

  Laboratory of Pharmaceutical Microbiology, Faculty of Medical and Pharmaceutical Sciences, Kumamoto

• Uyeda M

  Kumamoto Univ. Kumamoto Jpn

• Uyeda Masaru

  Laboratory Of Pharmaceutical Microbiology Faculty Of Medical And Pharmaceutical Sciences Kumamoto Un

• Uyeda Masaru

  Shokei University

• Uyeda Masaru

  Laboratory Of Medicinal Microbiology Faculty Of Pharmaceutical Sciences Kumamoto University

• Suzuki K

  Univ. Tokyo Tokyo

• SHIBATA Motoo

  Laboratory of Medicinal Microbiology, Faculty of Pharmaceutical Sciences, Kumamoto University

• SUZUKI KEITAROU

  Laboratory of Medicinal Microbiology, Faculty of Pharmaceutical Sciences Kumamoto University

• NAKANO Nahoko

  Faculty of Pharmaceutical Sciences, Kumamoto University

• SHIBATA Motoo

  Faculty of Pharmaceutical Sciences, Kumamoto University

• Suzuki Keitarou

  Laboratory Of Medicinal Microbiology Faculty Of Pharmaceutical Sciences Kumamoto University

• Suzuki K

  Department Of Nutritional Science Tokyo University Of Agriculture

• Udayama Manabu

  Faculty Of Pharmaceutical Sciences Kumamoto University

• NAKANO Nahoko

  Laboratory of Medicinal Microbiology, Faculty of Pharmaceutical Sciences, Kumamoto University

• TANAKA Rie

  Laboratory of Medicinal Microbiology, Faculty of Pharmaceutical Sciences, Kumamoto University

• Uyeda Masaru

  Department Of Pharmaceutical Microbiology Faculty Of Medical And Pharmaceutical Sciences Kumamoto Un

• Shibata Motoo

  Laboratory Of Medicinal Microbiology Faculty Of Pharmaceutical Sciences Kumamoto University

• Nakano Nahoko

  Faculty Of Pharmaceutical Sciences Kumamoto University

• Tanaka Rie

  Laboratory Of Medicinal Microbiology Faculty Of Pharmaceutical Sciences Kumamoto University

• Suzuki Kazuharu

  Department Of Nutritional Science Faculty Of Applied Bioscience Tokyo University Of Agriculture

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