Pentalenolactone I and Hygromycin A, Immunosuppressants produced by Streptomyces filipinensis and Streptomyces hygroscopicus

スポンサーリンク

概要

• 論文の詳細を見る

• Immunosuppressants isolated from Streptomyces filipinensis and S.hygroscopicus were identified with pentalenolactone I and hygromycin A, respectively. The compounds as well as cyclosporin A showed immunosuppressant activity in the mixed lymphocyte reaction, and pentalenolactone I and cyclosporin A suppressed IL-2 production, however, hygromycin A did not. Hygromycin A may have immunosuppressant activity by a different mechanism from pentalenolactone I, cyclosporin A and tacrolimus.

• 社団法人日本農芸化学会の論文
• 2001-05-23

著者

• Suzuki Kazuharu

  Department Of Nutritional Science Tokyo University Of Agriculture

• Suzuki Kazuharu

  東京農業大学 農学部栄養科学科

• YOKOMIZO Kazumi

  Faculty of Medical and Pharmaceutical Sciences, Kumamoto University

• UYEDA Masaru

  Faculty of Medical and Pharmaceutical Sciences, Kumamoto University

• Uyeda M

  Kumamoto Univ. Kumamoto Jpn

• Uyeda Masaru

  Laboratory Of Pharmaceutical Microbiology Faculty Of Medical And Pharmaceutical Sciences Kumamoto Un

• Uyeda Masaru

  Shokei University

• Yokoi Kaori

  School Of Agriculture Kyushu Tokai University

• Yokomizo K

  Kumamoto Univ. Kumamoto Jpn

• Udayama M

  Kumamoto Univ. Kumamoto Jpn

• SUZUKI Keitarou

  Faculty of Pharmaceutical Sciences, Kumamoto University

• Yokomizo Kazumi

  Laboratory Of Pharmaceutical Microbiology Faculty Of Medical And Pharmaceutical Sciences Kumamoto Un

• Yokomizo Kazumi

  Faculty Of Pharmaceutical Sciences Kumamoto University

• Suzuki K

  Univ. Tokyo Tokyo

• Suzuki Keitarou

  Faculty Of Pharmaceutical Sciences Kumamoto University

• Suzuki Kazushi

  Department Of Applied Biological Chemistry Faculty Of Agriculture Niigata University:(present Addres

• Suzuki K

  Department Of Nutritional Science Tokyo University Of Agriculture

• Udayama Manabu

  Faculty Of Pharmaceutical Sciences Kumamoto University

• MIZUKAMI Masafumi

  Faculty of Pharmaceutical Sciences, Kumamoto Untversity

• Mizukami Masafumi

  Faculty Of Pharmaceutical Sciences Kumamoto Untversity

• Uyeda Masaru

  Department Of Pharmaceutical Microbiology Faculty Of Medical And Pharmaceutical Sciences Kumamoto Un

• Kido Y

  Div. Of Instrumental Analysis Inst. Of Resource Dev. And Analysis Kumamoto Univ.

• Sakurai K

  Department Of Nutritional Science Tokyo University Of Agriculture

• Kido Y

  Faculty Of Pharmaceutical Sciences Kumamoto University

• Suzuki Kazuharu

  Department Of Nutritional Science Faculty Of Applied Bioscience Tokyo University Of Agriculture

• Kido Y

  Ube Research Laboratory Fujirebio Inc.

関連論文

• Hesperidin, a citrus flavonoid, inhibits bone loss and decreases serum and hepatic lipids in ovariectomized mice.
• Structures of Three New Oleanene Glucuronides Isolated from Lathyrus palustris var. pilosus and Hepatoprotective Activity
• A New Oleanene Glucuronide Having a Branched-Chain Sugar from Melilotus officinalis
• Anti-herpes Virus Type 1 Activity of Oleanane-Type Triterpenoids(Pharmacognosy)
• A New Lignan Glycoside and Phenylethanoid Glycosides from Strobilanthes cusia BREMEK
• Absence of Negative Feedback on Intestinal Magnesium Absorption on Excessive Magnesium Administration in Rats
• Dietary Iron Deficiency Decreases Serum Osteocalcin Concentration and Bone Mineral Density in Rats
• Effects of Lowering Food Intake by High Phosphorus Diet on Parathyroid Hormone Actions and Kidney Mineral Concentration in Rats
• Reduction in Dietary Calcium/Phosphorus Ratio Reduces Bone Mass and Strength in Ovariectomized Rats Enhancing Bone Turnover
• Effects of Dietary Phosphorus Intake on Bone Mineralization and Calcium Absorption in Adult Female Rats
• Decreased mRNA Expression of the PTH/PTHrP Receptor and Type II Sodium-Dependent Phosphate Transporter in the Kidney of Rats Fed a High Phosphorus Diet Accompanied with a Decrease in Serum Calcium Concentration
• Sex Differences in Kidney Mineral Concentrations and Urinary Albumin Excretion in Rats Given High-phosphorus Feed(Food & Nutrition Sience)
• Changes in N-Acetyl-β-D-Glucosaminidase Activity in the Urine and Urinary Albumin Excretion in Magnesium Deficient Rats(Food & Nutrition Science)
• Greater Effect of Dietary Potassium Tripolyphosphate than of Potassium Dihydrogenphosphate on the Nephrocalcinosis and Proximal Tubular Function in Female Rats from the Intake of a High-phosphorus Diet
• High P Diet Induces Acute Secretion of Parathyroidhormone without Alteration of Serum Calcium Levels in Rats
• Comparison of Various Phosphate Salts as the Dietary Phosphorus Source on Nephrocalcinosis and Kidney Function in Rats
• High Phosphorus Diet Rapidly Induces Nephrocalcinosis and Proximal Tubular Injury in Rats
• Phosphorus reduces renal receptivity for parathyroid hormone in rats
• Fattiviracin A1, a Novel Antiviral Agent Produced by Streptomyces microflavus Strain No. 2445 II. Biological Properties
• Fattiviracin A1, a Novel Antiherpetic Agent Produced by Streptomyces microflavus Strain No. 2445 I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Structure Elucidation
• Coexpression of the CUG-Binding Protein Reduces DM Protein Kinase Expression in COS Cells
• Overexpression, Purification, and Characterization of Human m-Calpain and Its Active Site Mutant, m-C105S-Calpain, Using a Baculovirus Expression System
• Anti-herpes Virus Activity of Fabaceous Triterpenoidal Saponins
• Anti-herpes Virus Activity of Solanum Steroidal Glycosides
• A New Antiherpetic Agent, AH-1763 IIa, Produced by Streptomyces cyaneus Strain No. 1763
• A New Antiherpetic Agent Produced by Streptomyces sp.Strain No.758
• Structures of Fattiviracin Family, Antiviral Antibiotics
• Identification of Endogenous Substrates for Drosophila Calpain from a Salt-Extracted Fraction of Drosophila Ovaries
• Oryzacystatins Exhibit Growth-inhibitory and Lethal Effects on Different Species of Bean Insect Pests, Callosobruchus chinensis (Coleoptera) and Riptortus clavatus (Hemiptera)
• Organization and Primary Sequence of Multiple Genes Encoding Type II mRNA Species of Rice Prepro-glutelin(Biological Chemistry)
• Effect of Validamycin on β-d-Glucan-degrading Enzymes from Rhizoctonia solani
• Partial Hydrolysis of Soyasaponin I and the Hepatoprotective Effects of the Hydrolytic Products. Study of the Structure-Hepatoprotective Relationship of Soyasapogenol B Analogs
• Preventive Effects of Saponins from Puerariae Radix (the root of Pueraria lobata OHWI) on in Vitro Immunological Injury of Rat Primary Hepatocyte Cultures
• Enhanced Production of Fattiviracins by Bacitracin-resistant Strains of Streptomyces microflavus Strain No. 2445
• Inhibitory Activities of(-)-Epigallocatechin-3-O-gallate against Topoisomerases I and II
• Topostatin, a Novel Inhibitor of Topoisomerases I and II Produced by Thermomonospora alba Strain No. 1520 III. Inhibitory Properties
• Topostatin, a Novel Inhibitor of Topoisomerases I and II Produced by Thermomonospora alba Strain No. 1520 II. Physico-chemical Properties and Structure Elucidation
• Topostatin, a Novel Inhibitor of Topoisomerases I and II Produced by Thermomonospora alba Strain No. 1520 I. Taxonomy, Fermentation, Isolation and Biological Activities
• Formation of a Chlorhexidine Degradation Intermediate through Pyruvate Incorporation by Pseudomonas sp.no.A-3
• CELL AGGREGATION FACTORS PRODUCED BY STREPTOMYCETES
• N-Long-chain Monoacylated Derivatives of 2,6-Diaminopyridine with Antiviral Activity
• Synthesis and Antiviral Activities of Some 4,4'- and 2,2'-Dihydroxytriphenylmethanes
• Synthesis and Antiviral Activities of Some 4,4'-Dihydroxytriphenylmethanes
• Synthesis of 2, 2'-Dihydroxybisphenols and Antiviral Activity of Some Bisphenol Derivatives
• Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the β-subunit of coatomer complex, β-COP
• Heterogeneous Nuclear Ribonucleoprotein K Interacts with and Is Proteolyzed by Calpain in vivo(Biochemistry & Molecular Biology)
• LysR-type Transcriptional Regulator ChiR Is Essential for Production of All Chitinases and a Chitin-Binding Protein, CBP21,in Serratia marcescens 2170
• Synthesis and Antiviral Activities of N-Mono- and/or N,N'-Di- Carbamoyl and Acyl Derivatives of Symmetrical Diamines
• N-Monocarbamoyl Derivatives of Symmetrical Diamines with Antiviral Activity
• Pentalenolactone I and Hygromycin A, Immunosuppressants produced by Streptomyces filipinensis and Streptomyces hygroscopicus
• Biosynthesis of Fattiviracin FV-8,an Antiviral Agent
• Antiviral Activity of Fattiviracin FV-8 against Human Immunodeficiency Virus Type 1 (HIV-1)
• Effects of DNA on the Formation of Cell Aggregate by a Microbial Hepatoma Aggregation Factor (HAF)
• Effects of Proteases on Hepatoma AH109A Cells Aggregated by a Microbial Hepatoma Aggregation Factor (HAF)
• HAF, Hepatoma Aggregation Factor Produced by Streptomyces sp. Strain No. A-6143(Biological Chemistry)
• 3315-AF2, a Cell Aggregation Factor Produced by Streptomyces sp. Strain No.A-3315(Biological Chemistry)
• Effects of Validamycin on Glucan Synthesis by Cell-free Extracts from Rhizoctonia solani(Biological Chemistry)
• Cell Aggregation Factor Produced by Streptomyces sp. Strain No.A-3315(Biological Chemistry)
• Characteristics and Action Mechanism of SAF, Cell Aggregation Factor Produced by Streptomyces murinus Strain No.A-2805(Biological Chemistry)
• SAF, a New Cell Aggregation Factor Produced by Streptomyces murinus Strain No. A-2805(Biological Chemistry)
• Characterization of B-1625 FA_, an Acidic Actinomycin Congener(Microbiology & Fermentation Industry)
• Morphological Mutant of Rhizoctonia solani and Its Cell Wall Component
• Serratia marcescens-Lytic Enzyme Produced by Micromonospor sp. Strain No. 152
• Partial Amino Acid Sequence of an Alkaline Protease Inhibitor, API-2 (b and c)
• MICROBIAL DEGRADATION OF DISINFECTANTS-ON THE DEGRADATION PATHWAYS OF CHLORHEXIDINE
• MICROBIAL DEGRADATION OF DISINFECTANTS MICROBIAL DEGRADATION OF CHLORHEXIDINE AND ITS DEGRADATION PATHWAY
• Microbial Degradation of Disinfectants. X Microbial Degradation of Chlorhexidine and Its Degradation Products (Proceedings of the 14th Symposium on Environmental Pollutants and Toxicology)
• Change in a Cell-Wall Component of Rhizoctonia solani Inhibited by Validamycin(Microbiology & Fermentation Industry)
• Chitinases A, B, and C1 of Serratia marcescens 2170 Produced by Recombinant Escherichia coli : Enzymatic Properties and Synergism on Chitin Degradation(Biochemistry & Molecular Biology)
• Chitin Binding Protein (CBP21) in the Culture Supernatant of Serratia marcescens 2170
• High Phosphorus Diet Changes Phosphorus Metabolism Regardless of PTH Action in Rats
• An Inhibitor of S-Hemolysin, SHI, Produced by Streptomyces sp. Strain No. 6288
• Purification and Some Properties of S-Hemolysin Produced by Streptomyces sp. Strain No. A-6288
• Molecular Cloning and Sequence Analysis of the Gene Encoding the Collagenase from Cytophaga sp. L43-1 Strain
• Purification and Properties of Collagenase from Cytophaga sp. L43-1 Strain
• Polymyxin B Enhances Formation of a New Pigment, a Peptide-Ferropyrimine Complex, in Serratia marcescens
• Isolation of a Serratia marcescens that Produces a Water-Soluble Reddish-violet Peptide Complex
• Purification and Some Properties of Chitinase B1 from Bacillus circulans WL-12
• Expression in Escherichia coli of the Bacillus circulans WL-12 Structural Gene for β-1, 3-Glucanase A(Microbiology & Fermentation Industry)
• Aspergillus oryzae palB^ Encodes a Calpain-Like Protease : Homology to Emericella nidulans PalB and Conservation of Functional Regions
• Dissociation of m-Calpain Subunits Occurs after Autolysis of the N-Terminus of the Catalytic Subunit, and Is Not Required for Activation
• Limited Proteolysis of Filamin Is Catalyzed by Caspase-3 in U937 and Jurkat Cells^1
• Autolysis of Calpain Large Subunit Inducing Irreversible Dissociation of Stoichiometric Heterodimer of Calpain
• Thimet Oligopeptidase Cleaves the Full-Length Alzheimer Amyloid Precursor Protein at a β-Secretase Cleavage Site in COS Cells^1
• Deletion of an Endosomal/Lysosomal Targeting Signal Promotes the Secretion of Alzheimer's Disease Amyloid Precursor Protein (APP)
• Potential Cosmetic Whitening Agents from Insect Cuticle : Tyrosinase Inhibitory Activity of N-Acetyldopamine Dimers from Exuviae of Cicada, Cryptotympana tustulata F_
• Isolation and Characterization of the Novel Lipophilic Protein, Pb CP-12.7,from the Shell of the Pink Shrimp, Pandalus borealis
• Hypoglycemic and Hypolipidemic Effects of Hesperidin and Cyclodextrin-Clathrated Hesperetin in Goto-Kakizaki Rats with Type 2 Diabetes
• Preventive Effects of Moringa oleifera (Lam) on Hyperlipidemia and Hepatocyte Ultrastructural Changes in Iron Deficient Rats
• An Assessment of the Antimicrobial Activity of Commercially Avaliable Disinfectants
• Combined effects of soy isoflavone and fish oil on ovariectomy-induced bone loss in mice
• Comparative Activities of the S-Enantiomer and Racemic Forms of Equol on Bone Fragility in Ovariectomized Mice
• Identification and Characterization of Component Organic and Glycosidic Acids of Crude Resin Glycoside Fraction from Calystegia soldanella
• Molecular Symmetry and Biological Activities of New Symmetrical Tris(2-aminoethyl)amine Derivatives
• New spirostanol glycosides from Solanum nigrum and S. jasminoides
• Saponins Esculeosides B-1 and B-2 in Italian Canned Tomatoes
• Flavonoids as a Possible Preventive of Dental Caries
• Calysolins V–IX, Resin Glycosides from Calystegia soldanella and Their Antiviral Activity toward Herpes
• Effect of Validamycin on Production of Some Enzymes in Rhizoctonia solani
• Calysolins X–XIII, Resin Glycosides from Calystegia soldanella, and Their Antiviral Activity toward Herpes Simplex Virus

もっと見る 閉じる

スポンサーリンク