Calysolins V–IX, Resin Glycosides from Calystegia soldanella and Their Antiviral Activity toward Herpes
スポンサーリンク
概要
- 論文の詳細を見る
Five new resin glycosides having macrolactone structures (jalapins), named calysolins V–IX (1–5), were isolated from the leaves, stems, and roots of Calystegia soldanella <span style="font-variant: small-caps;">ROEM.</span> et <span style="font-variant: small-caps;">SCHULT.</span> (Convolvulaceae). Their structures were determined on the basis of spectroscopic data as well as chemical evidence. The isolated compounds could be classified into two macrolactone types—one having a 22-membered ring (1–4) and the other with a 27-membered ring (5). The sugar moieties of 1–5 were found to exist in partially acylated forms comprising 2S-methylbutyric acid and tiglic acid. Compounds 4 and 5 are the first representatives of the calysolic acid C as the component glycosidic acid. Additionally, the antiviral activity of 1–5, together with calysolins I–IV and soldanelline B, which are previously isolated jalapins from this plant, toward herpes simplex virus type 1 was evaluated. All the compounds showed antiviral activity.
- 公益社団法人 日本薬学会の論文
著者
-
Kinjo Junei
Faculty Of Pharmaceutical Sciences Fukuoka University
-
YOKOMIZO Kazumi
Faculty of Medical and Pharmaceutical Sciences, Kumamoto University
-
Ono Masateru
School Of Agriculture Kyushu Tokai University
-
Okawa Masafumi
Faculty Of Pharmaceutical Sciences Fukuoka University
-
Kabata Kiyotaka
School Of Agriculture Tokai University
-
Yoshimitsu Hitoshi
Faculty Of Engineering Kyushu Kyoritsu University
-
Takigawa Ayako
School of Agriculture, Tokai University
-
Nohara Toshihiro
Faculty of Medical and Pharmaceutical Scieces, Sojo University
-
Kanemaru Yukiyo
School of Agriculture, Tokai University
-
Kawakami Gen
School of Agriculture, Tokai University
関連論文
- Microbial transformation and bioactivation of isoflavones from Pueraria flowers by human intestinal bacterial strains
- Delta(9)-tetrahydrocannabinol Enhances an Increase of Plasma Corticosterone Levels Induced by Forced Swim-Stress
- Pharmacological Study on the Novel Antinociceptive Agent, a Novel Monoterpene Alkaloid from Incarvillea sinensis(Pharmacognosy)
- A new lignan glucoside from the stems of Callicarpa japonica Thunb. var. luxurians Rehd.
- Five New Diterpenoids, Viteagnusins A-E, from the Fruit of Vitex agnus-castus
- HPLC Profile Analysis of Hepatoprotective Oleanene-Glucuronides in Puerariae Flos
- Three New Anti-Oxidative Saponarin Analogs from Young green Barley Leaves
- Structures of Three New Oleanene Glucuronides Isolated from Lathyrus palustris var. pilosus and Hepatoprotective Activity
- A New Oleanene Glucuronide Having a Branched-Chain Sugar from Melilotus officinalis
- Oleanene-Type Triterpene Glycosides from Puerariae Radix. IV. Six New Saponins from Pueraria lobata
- Oleanene-Type Triterpene Glycosides from Puerariae Radix. III.Three New Saponins from Pueraria thomsonii
- Antinociceptive Activities of α-Truxillic Acid and β-Truxinic Acid Derivatives(Pharmacognosy)
- Anti-inflammatory Activity of 4,4'-Dihydroxy-α-truxillic Acid(Pharmacognosy)
- Quantitative Determination of Incarvillateine in Incarvillea sinensis by Solid Phase Extraction and High Performance Liquid Chromatography
- Anti-inflammatory Activities of α-Truxillic Acid Derivatives and Their Monomer Components(Medicinal Chemistry)
- A Monoterpene Alkaloid from Incarvillea sinensis
- Two Novel Actinidine-Type Monoterpene Alkaloids from Incarvillea delavayi
- Studies on the Constituents of Gueldenstaedtia multiflora
- Three New Monoterpenoids from the Fruit of Genipa americana
- Trypanocidal Constituents in Plants 6. Minor Withanolides from the Aerial Parts of Physalis angulata
- ウスバサイシンAsiasarum sieboldii F. Maekawaの発芽特性
- Anti-herpes Virus Type 1 Activity of Oleanane-Type Triterpenoids(Pharmacognosy)
- New Bisabolane-Type Sesquiterpenes from the Aerial Parts of Lippia dulcis
- Trypanocidal Constituents in Plants 5. Evaluation of Some Mexican Plants for Their Trypanocidal Activity and Active Constituents in the Seeds of Persea americana(Pharmacognosy)
- Examination for Estrogenic Activities of Soyasaponin I and Related Compounds
- A New Lignan Glycoside and Phenylethanoid Glycosides from Strobilanthes cusia BREMEK
- Soy Isoflavone Metabolites Isolated from Human Urine
- Hepatoprotective Constituents in Plants 14. Effects of Soyasapogenol B, Sophoradiol, and Their Glucuronides on the Cytotoxicity of tert-Butyl Hydroperoxide to HepG2 Cells(Pharmacognosy)
- Sesquiterpenoids, Triterpenoids, and Flavonoids from the Fruits of Schinus molle
- Two new lignan glucosides from the fruit of Vitex cannabifolia
- Two Novel Antioxidant Ortho-Benzoyloxyphenyl Acetic Acid Derivatives from the Fruit of Vaccinium uliginosum
- Antiproliferative Activity of Phenylpropanoid Ester Glycosides from Ligustrum purpurascens
- Fattiviracin A1, a Novel Antiviral Agent Produced by Streptomyces microflavus Strain No. 2445 II. Biological Properties
- Fattiviracin A1, a Novel Antiherpetic Agent Produced by Streptomyces microflavus Strain No. 2445 I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Structure Elucidation
- Effects of Oleanane-Type Triterpenoids from Fabaceous Plants on the Expression of ICAM-1
- A New Antiherpetic Agent, AH-1763 IIa, Produced by Streptomyces cyaneus Strain No. 1763
- A New Antiherpetic Agent Produced by Streptomyces sp.Strain No.758
- Structures of Fattiviracin Family, Antiviral Antibiotics
- Partial Hydrolysis of Soyasaponin I and the Hepatoprotective Effects of the Hydrolytic Products. Study of the Structure-Hepatoprotective Relationship of Soyasapogenol B Analogs
- Antiproliferative Constituents in Plants 14. Coumarins and Acridone Alkaloids from Boenninghausenia japonica NAKAI(Pharmacognosy)
- Triterpene Saponins from Abrus cantoniensis (Leguminosae). II. Characterization of Six New Saponins Having a Branched-Chain Sugar
- Triterpene Saponins from Abrus cantoniensis (Leguminosae). I. Isolatioin and Characterization of Four New Saponins and a New Sapogenol
- Antioxidative Substances in the Leaves of Ligustrum purpurascens
- Microbial metabolism of soy isoflavones by human intestinal bacterial strains
- Antiproliferative Constituents from Umbelliferae Plants VII. Active Triterpenes and Rosmarinic Acid from Centella asiatica(Pharmacognosy)
- N-Long-chain Monoacylated Derivatives of 2,6-Diaminopyridine with Antiviral Activity
- Synthesis and Antiviral Activities of Some 4,4'- and 2,2'-Dihydroxytriphenylmethanes
- Synthesis and Antiviral Activities of Some 4,4'-Dihydroxytriphenylmethanes
- Synthesis of 2, 2'-Dihydroxybisphenols and Antiviral Activity of Some Bisphenol Derivatives
- Interactions of Phytoestrogens with Estrogen Receptors α and β(III). Estrogenic Activities of Soy Isoflavone Aglycones and Their Metabolites Isolated from Human Urine(Toxicology)
- Ursolic Acid as a Trypanocidal Constituent in Rosemary
- Activity-Guided Fractionation of Green Tea Extract with Antiproliferative Activity against Human Stomach Cancer Cells
- Antiproliferative Constituents in Plants 10. Flavones from the Leaves of Lantana montevidensis BRIQ. and Consideration of Structure-Activity Relationship
- Synthesis and Antiviral Activities of N-Mono- and/or N,N'-Di- Carbamoyl and Acyl Derivatives of Symmetrical Diamines
- N-Monocarbamoyl Derivatives of Symmetrical Diamines with Antiviral Activity
- Study of Structure-Hepatoprotective Relationships of Oleanene-Type Triterpenoidal Glucuronides Obtained from Several Fabaceous Plants on Rat Primary Hepatocyte Cultures
- Hepatoprotective and Hepatotoxic Actions of Oleanolic Acid-Type Triterpenoidal Glucuronides on Rat Primary Hepatocyte Cultures
- Pentalenolactone I and Hygromycin A, Immunosuppressants produced by Streptomyces filipinensis and Streptomyces hygroscopicus
- Biosynthesis of Fattiviracin FV-8,an Antiviral Agent
- Antiviral Activity of Fattiviracin FV-8 against Human Immunodeficiency Virus Type 1 (HIV-1)
- Hepatoprotective and Hepatotoxic Activities of Sophoradiol Analogs on Rat Primary Liver Cell Cultures
- Five Triterpene Glycosides from Oxytropis myriophylla
- Antiproliferative Constituents in the Plant 8. Seeds of Rhynchosia volubilis
- HPLC Profile Analysis of Oleanene-Glucuronides in Several Edible Beans
- DPPH(1, 1-Diphenyl-2-Picrylhydrazyl)Radical Scavenging Activity of Flavonoids Obtained from Some Medicinal Plants
- A New Diterpenoid Glucoside and Two New Diterpenoids from the Fruit of Vitex agnus-castus
- A New Oleanene Glucuronide Obatined from the Aerial Parts of Melilotus officinalis
- Two New Acyclic Diterpene Glycosides from Fruits of Habanero, Capsicum chinense
- Three new aromatic glycosides from the ripe fruit of cherry tomato
- Simultaneous analysis of isoflavones and saponins in Pueraria flowers using HPLC coupled to an evaporative light scattering detector and isolation of a new isoflavone diglucoside
- Four New Iridoid Glucosides from Ajuga reptans
- Oleanene Glycosides of the Aerial Parts and Seeds of Bupleurum falcatum and the Aerial Parts of Bupleurum rotundifolium, and Their Evaluation as Anti-hepatitis Agents
- Hepatoprotective Effects of Oleanene Glucuronides in Several Edible Beans
- Examination for Estrogenic Activities of Soyasaponin I and Related Compounds
- Soy Isoflavone Metabolites Isolated from Human Urine
- Antiproliferative Activity of Phenylpropanoid Ester Glycosides from Ligustrum purpurascens
- Antioxidative Substances in the Leaves of Ligustrum purpurascens
- HPLC Profile Analysis of Hepatoprotective Oleanene-Glucuronides in Several Soybean Processed Foods
- Garlicnin A from the Fraction Regulating Macrophage Activation of Allium sativum
- Three New Nortriterpene Glycosides and Two New Triterpene Glycosides from the Bulbs of Scilla scilloides
- Three New Diterpenoids from the Fruit of Vitex agnus-castus
- Five New Steroidal Glycosides from the Stems of Solanum sodomaeum
- Components of convolvulin from Quamoclit×multifida
- Development of an enzyme-linked immunosorbent assay to determine puerarin and its aglycone daidzein
- Screening of promising chemotherapeutic candidates against human adult T-cell leukemia/lymphoma from plants : active principles from Physalis pruinosa and structure-activity relationships with withanolides
- Garlicnins B1, C1, and D, from the Fraction Regulating Macrophage Activation of Allium sativum
- Three New Resin Glycosides and a New Tetrahydropyran Derivative from the Seeds of Quamoclit pennata
- Two New Nortriterpenoid Glycosides and a New Phenylpropanoid Glycoside from the Bulbs of Scilla scilloides
- Identification and Characterization of Component Organic and Glycosidic Acids of Crude Resin Glycoside Fraction from Calystegia soldanella
- Molecular Symmetry and Biological Activities of New Symmetrical Tris(2-aminoethyl)amine Derivatives
- Antioxidative and Antihyaluronidase Activities of Some Constituents from Foeniculi Fructus(Fruit of Foeniculum vulgare MILLER).
- Five New Nortriterpenoid Glycosides from the Bulbs of Scilla scilloides
- Cyclic Sulfoxides Garlicnins B2, B3, B4, C2, and C3 from Allium sativum
- Three Acylated Glycosidic Acid Methyl Esters and Two Acylated Methyl Glycosides Generated from the Convolvulin Fraction of Seeds of Quamoclit pennata by Treatment with Indium(III) Chloride in Methanol
- Characterization of Carotenoid Fatty Acid Esters from the Peels of the Persimmon Diospyros kaki
- Calysolins V–IX, Resin Glycosides from Calystegia soldanella and Their Antiviral Activity toward Herpes
- Five New Resin Glycoside Derivatives Isolated from the Convolvulin Fraction of Seeds of Quamoclit pennata after Treatment with Indium(III) Chloride in Methanol
- Calysolins X–XIII, Resin Glycosides from Calystegia soldanella, and Their Antiviral Activity toward Herpes Simplex Virus
- Four New Acylated Glycosidic Acid Methyl Esters Isolated from the Convolvulin Fraction of Seeds of Quamoclit pennata after Treatment with Indium(III) Chloride in Methanol