Antiproliferative Constituents in Plants 14. Coumarins and Acridone Alkaloids from Boenninghausenia japonica NAKAI(Pharmacognosy)
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概要
- 論文の詳細を見る
The MeOH extracts of the ground part and the root of Boenninghausenia japonica NAKAI showed inhibitory activity against tumor cell growth. Fractionation of the extracts has resulted in isolation of 1,3-dihydroxy-4-(2'-hydroxy-3'-hydroxymethyl-3',4'-epoxy-butyl)-N-methylacridone, 1,3-dihydroxy-4-[(Z)-3'-hydroxy-3'-methyl-buten-1'-yl]-N-methylacridone, 3-(1',1'-dimethylallyl)-7-hydroxy-8-methoxy-2H-1-benzopyran-2-one, casegravol, cis-casegravol, and edgeworin in addition to 9 compounds reported from B. japonica and B. albiflora. The isolates from this plant and some related compounds were tested for antiproliferative activity against human gastric adenocarcinoma (MK-1), human uterus carcinoma (HeLa), and murine melanoma (B16F10) cells.
- 公益社団法人日本薬学会の論文
- 2004-08-01
著者
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YAMAGATA Yuriko
Graduate School of Pharmaceutical Sciences, Kumamoto University
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KINJO Junei
Faculty of Pharmaceutical Sciences, Fukuoka University
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Kinjo Junei
Faculty Of Pharmaceutical Sciences Fukuoka University
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OKABE Hikaru
Faculty of Pharmaceutical Sciences, Fukuoka University
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Okabe Hikaru
Faculty Of Pharmaceutical Sciences Fukuoka University
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岡部 光
福岡大学
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CHAYA Norihito
Faculty of Pharmaceutical Sciences, Fukuoka University
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TERAUCHI Kazuko
Faculty of Pharmaceutical Sciences, Fukuoka University
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Yamagata Yuriko
Graduate School Of Pharmaceutical Sciences Kumamoto University
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Chaya Norihito
Faculty Of Pharmaceutical Sciences Fukuoka University
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Yamagata Y
Graduate School Of Pharmaceutical Sciences Kumamoto University
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Terauchi Kazuko
Faculty Of Pharmaceutical Sciences Fukuoka University
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