REACTION OF ORGANOMETALLIC REAGENTS WITH 2'- AND 3'-KETOURIDINE DERIVATIVES : SYNTHESIS OF URACIL NUCLEOSIDES BRANCHED AT THE 2'- AND 3'-POSITIONS(Communications to the Editor)

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概要

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• The reaction of organolithium, Grignard, and organoaluminum reagents with 2'- and 3'-ketouridine derivatives was examined. For the reaction of 2',5'-bis-O-(tert-butyldimethylsilylj-3'-ketouridine, both organolithiums and organoaluminums seem to be practically useful. But only organoaluminums gave satisfactory yields in the reaction of 3',5'-O-(tetraisopropyldisiloxan-1, 3-divl)-2'-ketouridine.

• 社団法人日本薬学会の論文
• 1987-06-25

著者

• 田中 博道

  School of Pharmaceutical Sciences, Showa University

• 宮坂 貞

  School of Pharmaceutical Sciences, Showa University

• 山口 健太郎

  千葉大学分析センター

• 山口 健太郎

  School of Pharmaceutical Sciences, Showa University

• 飯高 洋一

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• 山口 健太郎

  School Of Pharmaceutical Sciences Showa University

• 宮坂 貞

  昭和大学大学院薬学研究科医療薬学専攻

• 早川 弘之

  School of Pharmaceutical Sciences, Showa University

• 伊藤 直子

  School of Pharmaceutical Sciences, Showa University

• 中島 政子

  School of Pharmaceutical Sciences, Showa University

• 中島 政子

  School Of Pharmaceutical Sciences Showa University

• 宮坂 貞

  School Of Pharmaceutical Sciences Showa University

• 飯高 洋一

  Faculty Of Pharmaceutical Sciences The University Of Tokyo

• 伊藤 直子

  School Of Pharmaceutical Sciences Showa University

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