Studies on Heterocyclic Compounds. XX. The Reaction of the Oxazolo [3,2-b] pyridazinium Perchlorates with Hydrazines
スポンサーリンク
概要
- 論文の詳細を見る
On treatment with hydrazine hydrate (80%) and methylhydrazine, oxazolo [3,2-b] pyridazinium perchlorates (I) furnish hemi-perchlorates of 4H-pyridazino [6,1-c] [1,2,4] triazines (VI) and 1-methyl-4H-pyridazino [6,1-c] [1,2,4] triazinium perchlorates (VIII), respectively. On reaction with phenylhydrazine by refluxing in acetonitrile, I affords an osazone (XII), a phenylazopyridazine (XIII) and its hydrazo derivative (XIV), which are also formed from N-phenylamino-6-chloro-2-phenacyl-2,3-dihydropyridazin-3-ylideneimine phenylhydrazone (XV) by refluxing with phenylhydrazine in acetonitrile. In the reaction of I with hydrazines, it has been shown that the initial attack of the reagent always occurs at the C_<8a>-position to furnish various condensed pyridazine derivatives.
- 公益社団法人日本薬学会の論文
- 1982-05-25
著者
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宮坂 貞
School of Pharmaceutical Sciences, Showa University
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佐藤 和恵
School Of Pharmaceutical Sciences Showa University
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佐藤 和恵
昭和大学薬学部分析センター
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佐藤 和恵
昭和大学院薬
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宮坂 貞
School Of Pharmaceutical Sciences Showa University
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荒川 基一
School of Pharmaceutical Sciences, Showa University
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荒川 基一
School Of Pharmaceutical Sciences Showa University
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