The Formation of Cyclic Peroxide from Guaia-6,9-diene as a Model for Hanalpinol Biosynthesis

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概要

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• Autooxidation and photosensitized oxidation converted guaia-6,9-diene into hanalpinol, both compounds are contained in the rhizomes of Alpinia japonica. This process may be considered to be a biomimetic conversion. Guaia-6,9-diene may be regarded as an immediate precursor of hanalpinol, and a biogenetic pathway has been proposed. The results of molecular orbital calculation (modified neglect of differential overlap (MNDO) method) supported this proposal and provided a basis for conformational analysis.

• 社団法人日本薬学会の論文
• 1988-08-25

著者

• 飯高 洋一

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• 森田 博史

  Department of Pharmacognosy, Tokyo College of Pharmacy

• 糸川 秀治

  Department of Pharmacognosy, Tokyo College of Pharmacy

• 森田 博史

  Department Of Pharmacognosy School Of Pharmacy Tokyo University Of Pharmacy And Life Sciences

• 糸川 秀治

  東京薬科大学 薬学部

• 富岡 伸夫

  Faculty Of Pharmaceutical Sciences The University Of Tokyo

• 飯高 洋一

  西東京大・理工

• 飯高 洋一

  Faculty Of Pharmaceutical Sciences The University Of Tokyo

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