Structure of (+)-Epigriseofulvin

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概要

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• The crystal and molecular structure of (+)-epigriseofulvin were elucidated by X-ray structure analysis. The crystal belongs to a triclinic space group P1,with the unit cell parameters of a=11.718 (4), b=9.870 (3) Å, α=103.49 (3), β=102.38 (3), γ=96.26 (3)°, V=1061 (1) Å^3. The unit cell contains two crystallographically independent (+)-epigriseofulvin molecules and two chloroform molecules. The structure was solved by the direct method and refined to an R-value of 0.093 for 3971 non-zero reflections. No significant conformational differences between the two molecules were observed. The cyclohexenone rings take half-chair conformations with planar conjugated enone systems.

• 社団法人日本薬学会の論文
• 1985-01-25

著者

• 佐藤 良博

  共立薬科大学名誉

• 小田 泰子

  Kyoritsu College of Pharmacy

• 飯高 洋一

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• 佐藤 良博

  Kyoritsu College of Pharmacy

• 飯高 洋一

  School Of Medicine Teikyo University

• 岩間 正典

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 中村 涼美

  Kyoritsu College of Pharmacy

• 岩間 正典

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 飯高 洋一

  Faculty Of Pharmaceutical Sciences The University Of Tokyo

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