Effect of Estradiol and Ethynylestradiol on Microtubule Distribution in Chinese Hamster V79 Cells
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概要
- 論文の詳細を見る
The effects of estradiol (E_2) and ethynylestradiol (EE_2) on the chromosome number and cellular microtuble architecture of Chinese hamster V79 cells were studied using fluorescent anti-tubulin antibody. Treatment with 20μM E_2 for 48h induced only a small amount of tetraploid cells, but the normal microtubule network was disrupted completely by only 3h of treatment.This data reveals that E_2 has higher microtubule-disruptive activity than diethylstilbestrol in V79 cells.
- 社団法人日本薬学会の論文
- 1992-01-25
著者
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佐藤 美洋
北海道大学大学院薬学研究院
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佐藤 良博
共立薬科大学名誉
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小田 泰子
Kyoritsu College of Pharmacy
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榊原 由美子
Kyoritsu College of Pharmacy
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佐藤 良博
Kyoritsu College of Pharmacy
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Sato Y
Osaka Prefecture University
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Sato Y
(present Address)tsukuba Research Institute Banyu Pharmaceutical Co. Ltd.
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会津-横田 恵理子
Kyoritsu College of Pharmacy
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一ノ関 謙
Kyoritsu College of Pharmacy
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佐藤 嘉信
Department Of Chemical Engineering University Of Osaka Prefecture
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