SYNTHESIS OF A NEW POTENT ANTI-ANGIOGENIC AGENT, 17α-ACETOXY-9α-FLUORO-6α-METHYLPROGESTERONE
スポンサーリンク
概要
- 論文の詳細を見る
A new anti-angiogenic agent, 17α-acetoxy-9α-fluoro-6α-methylprogesterone (9α-fluoromedoroxyprogesterone acetate [FMPA, 9]) was synthesized in a 10-step sequence. FMPA (9) had about two orders of magnitude stronger antiangiogenic activity than medroxyprogesterone acetate (MPA), as estimated in a bioassay involving chorioallantoic membranes of growing chick embryos.
- 1997-02-15
著者
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佐藤 美洋
北海道大学大学院薬学研究院
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関川 善夫
Department Of Pharmaceutical Sciences National Institute Of Public Health
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Sato Y
Osaka Prefecture University
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CHOSHI Tominari
Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University
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Sato Y
(present Address)tsukuba Research Institute Banyu Pharmaceutical Co. Ltd.
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Sato Y
Kyoritsu College Of Pharmacy
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SUGINO Eiichi
Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University
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Uchida Masayuki
Meiji Dairies Co.
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Hibino Satoshi
Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University
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MURATA Natsuko
Pharmaceuticals Development Department, Meiji Dairies Corporation
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FUJIMORI Shiho
Pharmaceuticals Development Department, Meiji Dairies Corporation
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ICHIHARA Yoshitatsu
Pharmaceuticals Development Department, Meiji Dairies Corporation
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TSUBOI Hiroshi
Division of Research and Development, Meiji Dairies Corporation
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UCHIDA Masayuki
Division of Research and Development, Meiji Dairies Corporation
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OIKAWA Tsutomu
Faculty of Health and Social Work, Kanagawa University of Human Services
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SHIMAMURA Mariko
Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University
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Choshi Tominari
Fac. Of Pharmacy And Pharmaceutical Sciences Fukuyama Univ.
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Choshi Tominari
Fukuyama University Faculty Of Pharmacy And Pharmaceutical Sciences
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Choshi Tominari
Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
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Matsuura Nobuyasu
Dep. Of Life Sci. Fac. Of Sci. Okayama Univ. Of Sci.
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佐藤 嘉信
Department Of Chemical Engineering University Of Osaka Prefecture
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Yamaji Taketo
Division Of Research And Development Meiji Dairies Corporation
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Yamaji Taketo
Research And Development Center Division Of Research And Development Meiji Dailies Corporation
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Sugino E
Graduate School Of Pharmacy And Pharmaceutical Sciences Faculty Of Pharmacy And Pharmaceutical Scien
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Sugino Eiichi
Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
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TSUBOI Hiroshi
Meiji Institute of Health Science, Meiji Milk Products Co., Ltd.,
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Hibino Satoshi
Fac. Of Pharmacy And Pharmaceutical Sciences Fukuyama Univ.
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Hibino Satoshi
Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
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Fujimori S
Pharmaceuticals Development Department Meiji Dairies Corporation
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Oikawa T
Faculty Of Health And Social Work Kanagawa University Of Human Services
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Oikawa Tsutomu
Department Of Cancer Therapeutics The Tokyo Metropolitan Institute Of Medical Science (rinshoken)
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Tsuboi Hiroshi
Division Of Research And Development Meiji Dairies Corporation
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Tsuboi Hiroshi
Meiji Institute Of Health Science Meiji Milk Products Co. Ltd.
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Shimamura M
Department Of Cancer Therapeutics The Tokyo Metropolitan Institute Of Medical Science (rinshoken)
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Shimamura Mariko
Department Of Cancer Therapeutics The Tokyo Metropolitan Institute Of Medical Science (rinshoken)
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FUJIMORI Shiho
Meiji Institute of Health Science, Meiji Milk Products Co., Ltd.,
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ICHIHARA Yoshitatsu
Meiji Institute of Health Science, Meiji Milk Products Co., Ltd.,
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SATO Yoshio
Meiji Institute of Health Science, Meiji Milk Products Co., Ltd.,
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YAMAJI Taketo
Meiji Institute of Health Science, Meiji Milk Products Co., Ltd.,
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MURATA Natsuko
Meiji Institute of Health Science, Meiji Milk Products Co., Ltd.,
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Iitaka Y
Pharmaceuticals Development Department Meiji Dairies Corporation
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Murata Natsuko
Department Of Life Science Faculty Of Science Okayama University Of Science
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Sato Yoshio
Meiji Institute Of Health Science Meiji Milk Products Co. Ltd.
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Murata Natsuko
Meiji Dairies Corporation
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Yamaji Taketo
Meiji Dairies Corporation
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