Nuclear Factor κB Inhibition by Dibenzoylmethane Derivatives
スポンサーリンク
概要
- 論文の詳細を見る
We established stable HeLa transformants with reporter genes containing nuclear factor (NF)-κB response elements to measure NF-κB inhibition. Tumor necrosis factor (TNF)-α treatment induced a 6-fold activation of NF-κB in HeLa_<NF-κB>-3 cells. Three chloro-derivatives of fourteen dibenzoylmethane derivatives inhibited NF-κB activity.
- 公益社団法人日本薬学会の論文
- 2009-04-01
著者
-
Murakami Rika
Research Planning Department Division Of Research And Development Meiji Dairies Corporation
-
Murakami Rika
Research And Development Center Division Of Research And Development Meiji Dailies Corporation
-
Matsuura Nobuyasu
Department Of Life Science Faculty Of Science Okayama University Of Science
-
CHOSHI Tominari
Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University
-
Hibino Satoshi
Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University
-
Yamada Masashi
Product Research, Licensing and Alliance Management, Taiho Pharmaceutical Co., Ltd.
-
Katayama Tomoyuki
Department of Life Science, Faculty of Science, Okayama University of Science
-
Choshi Tominari
Fac. Of Pharmacy And Pharmaceutical Sciences Fukuyama Univ.
-
Choshi Tominari
Fukuyama University Faculty Of Pharmacy And Pharmaceutical Sciences
-
Choshi Tominari
Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
-
Hibino Satoshi
Fac. Of Pharmacy And Pharmaceutical Sciences Fukuyama Univ.
-
Hibino Satoshi
Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
-
Katayama Tomoyuki
Department Of Life Science Faculty Of Science Okayama University Of Science
-
Yamada Masashi
Product Res. Licensing And Alliance Management Taiho Pharmaceutical Co. Ltd.
-
Murata Natsuko
Department Of Life Science Faculty Of Science Okayama University Of Science
-
Katayama Tomoyuki
Department Of Cardiology Kouseikai Hospital
関連論文
- Anti-Glycation Effect of Mixed Herbal Extract in Individuals with Pre-Diabetes Mellitus : A Double-Blind, Placebo-Controlled, Parallel Group Study
- A Carbazole Derivative Protects Cells Against Endoplasmic Reticulum (ER) Stress and Glutathione Depletion
- PJ-379 Clinical Manifestations and Outcome of Acute Myocardial Infarction in Young Adults Treated with Primary Coronary Angioplasty(PJ064,ACS/AMI (Clinical/Diagnosis) 2 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Cir
- PJ-378 The Etiology of Smoker's Paradox in Acute Myocardial Infarction, Especially Association with Low Grade Inflammation(PJ064,ACS/AMI (Clinical/Diagnosis) 2 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation
- PJ-104 Clinical Manifestations, Outcome, and Useful Strategy of Acute Myocardial Infarction in Women(PJ018,ACS/AMI (Clinical/Treatment) 1 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-169 Predictors of Sub-acute Stent Thrombosis in Acute Myocardial Infarction Patients Following Primary Coronary Stenting with Bare Metal Stent(Acute myocardial infarction, clinical (diagnosis/treatment)-8, The 71st Annual Scientific Meeting of the Japa
- PJ-146 Clinical Manlfestations and Outcome of Acute Myocardial Infarction in Women Treated with Primary Coronary Angioplasty(Acute coronary syndrome, basic/clinical-7, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-023 The Relationship between Acute Phase Serum Amyloid A (SAA) Concentrations and Left Ventricular Systolic Function in Acute Myocardial Infarction Patients(Acute myocardial infarction, clinical (pathophysiology)-4, The 71st Annual Scientific Meeting o
- PJ-012 Clinical Manifestations and Outcome of Acute Myocardial Infarction in Young Adults Treated with Primary Coronary Angioplasty(Acute myocardial infarction, clinical (diagnosis/treatment)-6, The 71st Annual Scientific Meeting of the Japanese Circulati
- Serum Amyloid A Protein as a Predictor of Cardiac Rupture in Acute Myocardial Infarction Patients Following Primary Coronary Angioplasty(CLINICAL INVESTIGATION)
- PJ-292 Serum Amyloid A protein as a Predictor of Cardiac Rupture in Acute Myocardial Infarction Patients Following Primary Coronary Angioplasty(Acute coronary syndrome, basic/clinical-6 (IHD) PJ49,Poster Session (Japanese),The 70th Anniversary Annual Scie
- OJ-355 Clinical Outcomes and Left Ventricular Function in Diabetic Patients with Acute Myocardial Infarction Treated with Primary Coronary Angioplasty(Acute myocardial infarction, clinical (diagnosis/treatment)-4 (IHD) OJ60,Oral Presentation (Japanese),Th
- OJ-095 The Prognostic Value of Serum Amyloid A Protein in Patients with Acute Myocardial Infarction(Acute myocardial infarction, clinical (diagnosis/treatment)-3 (IHD) OJ16,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the
- Predictors of Sub-Acute Stent Thrombosis in Acute Myocardial Infarction Patients Following Primary Coronary Stenting With Bare Metal Stent
- Prognostic Value of Serum Amyloid A Protein in Patients With Acute Myocardial Infarction
- Clinical Significance of Acute-Phase Endothelin-1 in Acute Myocardial Infarction Patients Treated With Direct Coronary Angioplasty
- Simultaneous Determination of Glycyrrhizin Metabolites Formed by the Incubation of Glycyrrhizin with Rat Feces by Semi-micro High-Performance Liquid Chromatography
- Two-chambered Right Ventricle : Report of Four Cases with Special Reference to the Clinical Diagnosis
- Effect of Exercise and Acetylcholine on the Pulmonary Circulation in Mitral and Congenital Heart Disease : Part I
- Electrocardiographic and Histological Studies on the Ligation of the Anterior and Posterior Septal Arteries in the Dog (II)
- A Potent Apoptosis-Inducing Activity of a Sesquiterpene Lactone, Arucanolide, in HL60 Cells : a Crucial Role of Apoptosis-Inducing Factor
- PE-393 BNP, Endothelin, and Norepinephrine in Patients with Diastolic Heart Failure(Heart failure, clinical-10 (M) PE66,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- OE-152 Plasma Aldosterone Concentration in Patients with Acute Myocardial Infarction(Acute myocardial infarction, clinical (diagnosis/treatment)-2 (IHD) OE26,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circul
- Prognostic Significance of Time-delay to Peak Creatine Kinase After Direct Percutaneous Coronary Interventionin Acute Myocardial Infarction Patients (Acute Myocardial Infarction, Clinical (Diagnosis/Treatment) 6 (IHD), The 69th Annual Scientific Meeting o
- Impact of Preprocedual TIMI Flow Grade 2 on Coronary Microcirculation and Left Ventricular Remodelig in Patients with Acute Myocardial Infarction(Acute Myocardial Infarction, Clinical (Pathophysiology) 3 (IHD), The 69th Annual Scientific Meeting of the Ja
- The Clinical Significance of Acute-phase Endothelin-1 in Acute Myocardial Infarction Treated With Direct Coronary Angioplasty(Acute Myocardial Infarction, Clinical (Diagnosis/Treatment) 11 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulat
- Cardiovascular Peptides as Predictors of Mortalityin Acute Myocardial Infarction Patients With Associated Cardiogenic Shock(Acute Myocardial Infarction, Clinical (Diagnosis/Treatment) 8 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation
- Indocarbazostatins C and D, New Inhibitors of NGF-induced Neuronal Differentiation in PC12 Cells
- Effect of Cry-consensus Peptide, a Novel Recombinant Peptide for Immunotherapy of Japanese Cedar Pollinosis, on an Experimental Allergic Rhinitis Model in B10.S Mice
- Cry-Consensus Peptide, a Novel Peptide for Immunotherapy of Japanese Cedar Pollinosis, Induces Th1-Predominant Response in Cry j 1-Sensitized B10.S Mice(Pharmacology)
- Efficacy of Dibenzoylmethane Derivatives in Protecting against Endoplasmic Reticulum Stress and Inhibiting Nuclear Factor Kappa B on Dextran Sulfate Sodium Induced Colitis in Mice
- Nuclear Factor κB Inhibition by Dibenzoylmethane Derivatives
- Synthesis and Anti-tumor Activity of a Fluorinated Analog of Medroxyprogesterone Acetate (MPA), 9α-Fluoromedroxyprogesterone Acetate (FMPA)
- Inhibition of Preadipocyte Differentiation by Germacranolides from Calea urticifolia in 3T3-L1 Cells
- Cloning of the Gene Cluster Responsible for the Biosynthesis of Brasilicardin A, a Unique Diterpenoid
- SYNTHESIS OF A NEW POTENT ANTI-ANGIOGENIC AGENT, 17α-ACETOXY-9α-FLUORO-6α-METHYLPROGESTERONE
- Lipase-Catalyzed Asymmetric Synthesis of Desprenyl-carquinostatin A and Descycloavandulyl-lavanduquinocin
- The Absolute Configuration of (+)-Oxopropaline D by Theoretical Calculation of Specific Rotation and Asymmetric Synthesis
- Chemical and Histoiogical Studies of Collagen Contents on Blood Vessels (I) The Collagen Contents of Human Aorta
- RIGHT BUNDLE BRANCH BLOCK WITH LEFT HEMIBLOCK AND ITS RELATION TO COMPLETE HEART BLOCK
- RELATIONSHIP BETWEEN ELECTROCARDIOGRAPHIC FINDINGS OF LEFT ATRIAL OVERLOADING AND LEFT ATRIAL VOLUME AND PRESSURE
- Purification and Catalytic Properties of a Tetrameric Carbony1 Reductase from Rabbit heart
- Cardio-protective Effects of Intravenous Magnesium Sulfate for Acute Myocardial Infarction
- Novel Syntheses of Murrayaquinone A and Furostifoline through 4-Oxygenated Carbazoles by Allene-Mediated Electrocyclic Reactions Starting from 2-Chloroindole-3-carbaldehyde
- The Enantioselective Total Synthesis of a β-Carboline Alkaloid, (S)-(-)-Dichotomine C(Communication to the Editor)
- Suppression of Laser-Induced Choroidal Neovascularization by Subconjunctival Injection of 9α-Fluoromedroxyprogesterone Acetate (FMPA), an Anti-angiogenic Agent, in Rats(Pharmacology)
- Synthesis of the New Furo [3, 2-h] isoquinoline Alkaloid, TMC-120B from Aspergillus ustus
- New Syntheses of Murrayaquinone A and Furostifoline
- Total Syntheses of Novel Cytocidal β-Carboline Alkaloids, Oxopropalines D and G
- New Regioselective Total Syntheses of Antibiotic Renierol, Renierol Acetate, and Renierol Propionate from the 5-Oxygenated Isoquinoline
- Synthesis of the Interferon-α Inducer Imiquimod by Thermal Electrocyclic Reactions of 1- and 2-Azahexatriene Systems
- Effects of 4-Ethylamino-2-butynyl(2-cyclohexyl-2-phenyl)glycolate Hydrochloride, a Metabolite of Oxybutynin, on Bladder Specimens and Rhythmic Bladder Contraction in Rats in Comparison With Oxybutynin
- Role of Acute-phase Inflammatory Reactants in Acute Myocardial Infarction
- P734 Acetylcholine Provocation Test IN Hypertrophic Nonobstructive Cardiomyopathy (HNCM) : A Comparison Of Clicical Findings Between Patients With Spasm And Without Spasm
- Total Synthesis of (±)-Carquinostatin A, and Asymmetric Total Synthesis of (R)-(-)-Carquinostatin A and (S)-(+)-Carquinostatin A
- Q Wave and Non-Q Wave Myocarditis with Special Reference to Clinical Significance.
- γ-Mangostin from Garcinia Mangostana Pericarps as a Dual Agonist That Activates Both PPARα and PPARδ