Preparation of Monomethyl Ether Derivatives of (+)-, (-)- and (±)-Indenestrols A and B
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概要
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In order to evaluate the contribution of the two phenolic hydroxyl groups to the biological activities of indenestrols A (IA) and B (IB), monomethyl ether derivatives of IA and IB were prepared and each enantiomer was separated to >99% purity by high-pressure liquid chromatography using a chiral column. The structures of the enantiomers were confirmed by proton and carbon-13 nuclear magnetic resonance and circular dichroism spectroscopic studies.
- 公益社団法人日本薬学会の論文
- 1993-10-15
著者
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