GANODERIC ACID AND ITS DERIVATIVES AS CHOLESTEROL SYNTHESIS INHIBITORS
スポンサーリンク
概要
- 論文の詳細を見る
Oxygenated lanosterol derivatives, which were isolated from Ganoderma lucidum (Polyporaceae) or their derivatives obtained by chemical conversion, were tested for their effect on cholesterol biosynthesis from 24,25-dihydrolanosterol by rat hepatic subscellular 10,000 x g supernatant fraction. The sterol (VI, 40 μM) with 7-oxo and 15α-hydroxy groups potently inhibited the synthesis of cholesterol from [24,25-^3H]-24,25-dihydrolanosterol (18 μM).
- 公益社団法人日本薬学会の論文
- 1989-02-25
著者
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佐藤 良博
共立薬科大学名誉
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菰田 泰夫
Research Institute for Medical and Dental Engineering, Tokyo Medical and Dental University
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園田 よし子
Kyoritsu College of Pharmacy
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佐藤 良博
Kyoritsu College of Pharmacy
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清水 正人
Research Institute For Medical And Dental Engineering Tokyo Medical And Dental University
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佐藤 良博
共立薬大
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菰田 泰夫
医歯大・医用研・化学
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菰田 泰夫
Institute For Medical And Dental Engineering Tokyo Medical And Detal University
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