Anti-Platelet Aggregation Principles from the Bark of Fraxinus japonica BLUME
スポンサーリンク
概要
- 論文の詳細を見る
The methanol extract of the bark of Fraxinus japonica BLUME was fractionated with the guidance of inhibitory activity on rabbit platelet aggregation induced by arachidonic acid. The following active principles were identified : 3-methoxy-4-hydroxyphenylethanol (I) (which also exists in the animal body as a dopamine metabolite), p-hydroxyphenylethanol (II), 2,6-dimethoxy-p-benzoquinone (III), compounds (IV), (V), and esculetin.
- 公益社団法人日本薬学会の論文
- 1981-08-25
著者
-
菰田 泰夫
Institute for Medical and Dental Engineering, Tokyo Medical and Dental University
-
中嶋 暉躬
Institute of Pharmaceutical Sciences, School of Medicine, Hiroshima University
-
中嶋 暉躬
Suntory Institute For Bioorganic Research
-
石川 正幸
Research Institute For Medical And Dental Engineering Tokyo Medical And Dental University
-
石川 正幸
Institute For Medical And Dental Engineering Tokyo Medical And Dental University
-
菰田 泰夫
医歯大・医用研・化学
-
菰田 泰夫
Institute For Medical And Dental Engineering Tokyo Medical And Detal University
-
小平 治良
Institute for Medical and Dental Engineering, Tokyo Medical and Dental University
-
小平 治良
Institute For Medical And Dental Engineering Tokyo Medical And Dental University
-
菰田 泰夫
Institute For Medical And Dental Engineering Tokyo Medical And Dental University
関連論文
- ユージノールおよびその関連化合物とりん脂質リポソームとの相互作用のDSC, NMRスペクトルによる研究
- 高性能液体クロマトグラフィーによるデアシルギムネマ酸の定量分析
- Structures of New Terpenoid Constituents of Ganoderma lucidum (Fr.) KARST (Polyporaceae)
- The Biologically Active Constituents of Ganoderma lucidum (FR.) KARST. Histamine Release-Inhibitory Triterpenes
- ホスファチジルコリン/コレステロールリポソームとの相互作用により誘起されるBis-GMA及びその関連メタクリレートの^1H-NMRケミカルシフトの変化
- メタクリレートとりん脂質及びりん脂質コレステロールリポソーム系との相互作用により誘起されるメタクリレートのNMRケミカルシフトの変化
- 5.慢性腎不全患者のカルシウム代謝及び骨変化(ビタミンD不応性重症くる病)に対する1α-OH-D_3の治癒効果(JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY Vol.21NO.4(August, 1975) : 掲載論文要旨)
- Active Peptides on Smooth Muscle in the Skin of Bombina orientalis BOULENGER and Characterization of a New Bradykinin Analogue
- Hydroboration of Steroidal-1,5-dien-3β-ols : A General Procedure for the Introduction of a Hydroxyl Group at 1α-Position of the 3-Oxygenated Steroids
- 2.1α-Hydroxyvitamin D_3(1α-OH-D_3)の合成とその生理作用(脂溶性ビタミン総合研究委員会 : 第146回会議研究発表要旨)
- 22 1α-Hydroxyvitamin D_3(1α-OH-D_3)の合成とその生理作用
- Structural Confirmation of the Nitration Product of the 1(2H)-Phthalazinone as the 2-Nitro-1(2H)-phthalazinone
- Plant Growth Regulators in the Pea Plant (Pisum sativum L.)
- Isolation of a Plant Growth Inhibitory Substance from Garden Peas (Pisum sativum L.) and Its Identification with (+)-Abscisin-II
- Studies on Hypotensive Agents. Synthesis of 1-Substituted 3-(2-Chlorophenyl)-6-ethoxycarbonyl-5,7-dimethyl-2,4(1H, 3H)-quinazolinediones
- Synthesis and Inhibitory Effect on Platelet Aggregation of 2-Phenyl-1 (2H)-phthalazinone Derivatives
- NEW HYPOTENSIVE AGENTS
- Studies on Antiatherosclerotic Agents. IX. Synthesis of 7-Ethoxycarbonyl-4-hydroxymethyl-6,8-dimethyl-1(2H)-phthalazinone (EG 626)
- Studies on Antiatherosclerotic Agents. VIII. Synthesis and Structure-Activity Relationship of 4-Hydroxymethyl-1(2H)-phthalazinone Derivatives
- 抗動脈硬化剤の合成研究-2-フタラジノン類のカルバメ-ト誘導体の合成
- 26 Cholesterolからの1α,25-Dihydroxycholecalciferol〔1α,25(OH)_2-D_3〕の合成
- Synthesis of 2β-Hydroxycholecalciferol [2β-OH-D_3]
- 29.コウヤマキより得られる二種のmacrocyclic diterpenesの構造
- Studies on Peptides. CI. Synthesis of a Wasp Venom, Mastoparan M
- Synthesis of Granuliberin-R and Various Fragment Peptides and Their Histamine-Releasing Activities
- Studies on Peptides. LXXXIV. Synthesis of the Tetradecapeptide Amide corresponding to the Wasp Venom, Mastoparan X
- A New Mast Cell Degranulating Peptide Homologous to Mastoparan in the Venom of Japanese Hornet (Vespa xanthoptera)
- A New Mast Cell Degranulating Peptide "Mastoparan" in the Venom of Vespula lewisii
- Synthesis of Granuliberin-R, a New Frog Skin Peptide from Rana rugosa
- The Studies on the Active Peptide on Smooth Muscle in the Skin of Rana rugosa, Thr^6-Bradykinin and Its Analogous Peptide, Ranakinin-R
- ISOLATION FROM HUMUS AND IDENTIFICATION OF TWO GROWTH PROMOTERS, ADENOSINE AND 2'-DEOXYADENOSINE, EFFECTIVE IN CULTURING THE DIATOM PHAEODACTYLUM TRICORNUTUM
- 3Dp-10 堆肥中に含まれる珪藻 Phaeodactylum tricornutum の増殖促進物質
- 歯とくすり
- Stereochemistry of Methyl 2-Benzyl-3-methoxycarbonyl-9-methyl-1,2,3,4-tetrahydro-9H-pyrido [3,4-b] indole-1-propionate
- Studies on the N-Oxides of π-Deficient N-Heteroaromatics. XXIV. Photochemistry of Acridine 10-Oxides (1)
- Photochemistry of Heterocyclic Compounds. (5). The Photolysis of 9-Cyanoacridine 10-Oxides : The Synthesis of Benzo [c]-2-aza-1,6-oxido [10] annulenes, Oxepino [2,3-b] quinolines, and 11-Cyano-6-oxo-6H-azepino [a] indoles
- Photochemistry of Heterocyclic Compounds. (4). Solvent Effects in the Photolysis of Tetrahydroacridine 10-Oxide Derivatives
- Three-membered Ring System with Two Hetero Atoms. VI. Photochemical Synthesis of 1aH-Osazirino[2,3-α]quinoxaline Derivatives and Their Thermal Reactions
- Photochemistry of the N-Oxides of Azanaphthalene and Their Substituted Derivatives
- Structure of Paragracine, A Biological Active Marine Base from Parazoanthus gracilis (Lwowsky)
- Structures of Biologically Active Minor Bases Related to Paragracine from Parazoanthus gracilis LWOWSKY
- Asymmetric Synthesis and Absolute Configuration of (-)-Trypargine
- Isolation and Identification of Anti-platelet Aggregation Principles from the Bark of Fraxinus japonica BLUME
- A New Synthesis of (±)-Trypargine
- ASYMMETRIC SYNTHESIS OF (1S)-(-)-TRYPARGINE
- Total Synthesis of (-)-Trypargine
- Chemistry of Paragracine, A biologically Active Marine Base from Parazoanthus gracilis (LWOWSKY)
- Anti-Platelet Aggregation Principles from the Bark of Fraxinus japonica BLUME
- Prostaglandin F_ from the Japanese Coastal Gorgonian, Euplexaura erecta
- 34 センナリスナギンチャク(Parazoanthus gracilis)に含まれる新生理活性物質,Paragracineについて
- Photochemical Rearrangement of Quinaldine 1-Oxide
- Studies on Antiatherosclerotic Agents. Synthesis and Inhibitory Activities on Platelet Aggregation of 4-Aryl Derivatives of 7-Ethoxycarbonyl-6,8-dimethyl-1(2H)-phthalazinone
- Studies on Antiatherosclerotic Agents. Synthesis of 5-Substituted Derivatives of 7-Ethoxycarbonyl-6,8-dimethyl-1(2H)-phthalazinone
- Studies on Antiatherosclerotic Agents. Synthesis of 7-Ethoxycarbonyl-4-formyl-6,8-dimethyl-1(2H)-phthalazinone Derivatives and Related Compounds
- Studies on Vazoactive Heterocyclic Compounds. : Preparation and Evaluation of the Hypotensive and Antiaggregating Activities of Phthalazinol Nitrates
- 抗動脈硬化剤の合成研究-7-置換キナゾリノン類のメチルカルバメ-トの合成
- 抗動脈硬化剤の合成研究-6-置換フタラジノン類のカルバメ-ト誘導体の合成
- 抗動脈硬化剤の合成研究-3-キナゾリン類のカルバメ-ト誘導体の合成
- 抗動脈硬化剤の合成研究-1-ダイアジン類のカルバメ-ト誘導体の合成
- Proton Nuclear Magnetic Resonance Studies of the Complexation of Zinc(II) with Glycyl-L-histidylglycine
- CATALYTIC ACTIVITIES AND COORDINATION ENVIRONMENTS OF THE COPPER IONS IN THE IMIDAZOLE CLUSTERS OF HISTIDINE-PEPTIDES, HIS(HIS)_nGLY AND N-ACETYL-HIS(HIS)_nGLY (n = 3,8,and 18)
- Analysis of Aldoses and Alditols by Capillary Gas Chromatography as Alditol Trifluoroacetates
- Comparative Studies on Angiotensins. VI. Structure of Angiotensin I produced by Renal Renin of the Dog, Guinea Pig and Rabbit, and Re-examination of the Peptides of the Pig, Horse and Ox using Homologous Renin Sources
- Studies on Peptides. CVI. Synthesis of a Physalaemin-like Peptide, [Lys^5,Thr^6]-Physalaemin, isolated from the Skin of a Frog, Uperoleia rugosa
- Comparative Studies on Angiotensins. V. Structure of Angiotensin formed by the Kidney of Japanese Goosefish and Its Identification by Dansyl Method
- Comparative Studies on Angiotensins. IV. Structure of Snake (Elaphe climocophora) Angiotensin
- Comparative Studies on Angiotensins. III. Structure of Fowl Angiotensin and Its Identification by DNS-Method
- Comparative Studies on Angiotensins. II. Structure of Rat Angiotensin and Its Identification by DNS-Method
- On the Third Active Peptide on Smooth Muscle in the Skin of Rana nigromaculata HALLOWELL
- The Studies on the Active Peptide in the Skin of Rana rugosa. II. The Structure of Ranatensin-R, the New Ranatensin Analogue, and Granuliberin-R, the New Mast Cell Degranulating Peptide
- GANODERIC ACID AND ITS DERIVATIVES AS CHOLESTEROL SYNTHESIS INHIBITORS
- Synthesis of Bradykinyl-Val-Ala-Pro-Ala-Ser-OH and Its Biological Properties
- Chemical Investigation of the Hornet (Vespa xanthoptera CAMERON) Venom. The Structure of a New Bradykinin Analogue "Vespakinin-X"
- Vespakinin-M, a Novel Bradykinin Analogue Containing Hydroxyproline, in the Venom of Vespa mandarinia SMITH
- A-16 歯科用接着性モノマーとCa^相互作用のNMR研究 : 4-MET及びその関連化合物について
- 歯科用接着剤Methacryloyloxydecyl Dihydrogen Phosphate (MDP)とりん脂質リポソール相互作用のNMRスペクトロスコピー研究 (続報)
- A-5 りん脂質/歯科用接着性モノマーリポソームシステムのNMR-ケミカルシフトに及ぼすpHの影響
- 歯科用接着性モノマー(N-methacryloyloxy-5-aminosalicylic acid, MASA)の溶血性及びりん脂質リポソームとの相互作用のNMR,DSC研究
- A-33 歯科用接着性モノマー(N-methacryloyloxy-5-aminosalicylic acid, MASA)の溶血性とMASA/りん脂質リポソーム相互作用のNMR及びDSC研究
- 歯科用接着性モノマー(4-methacryloyloxyethoxycarbonylphthalic Anhydride, 4-META)の溶血性とNMR,DSCによる4-META/りん脂質リポソームの相互作用
- A-8 歯科用接着性モノマー(4-META)の溶血性とNMR、DSCによる4-META/りん脂質リポソームの相互作用
- HPLCによる歯科用ボンディング剤からのMethacryloyloxydecyl Dihydrogen Phosphateの分離に関する研究
- Ableitung von Dihydrocinchonamin aus Cinchonidin
- Synthese von Derivaten der Cinchona-Alkaloide. XXXI. Ableitung der Alkaloide des Corynanthein-Typus aus Chinin.
- Ableitung von Dihydrocorynanthean und 3-Epidihydrocorynanthean aus Cinchonin.
- Ableitung des 10-Methoxydihydrocorynantheans aus Chinin.
- 7.規那塩基の変換
- Synthese von Derivaten der Cinchona-Alkaloide. XXVII. Ableitung von Dihydrocinchonamin aus Cinchonin.
- Synthese von Dihydrocinchonamin aus Dihydrocinchonin
- 規那塩基誘導体の合成研究(第24報) : 2'-Oxohexahydrochininのラクタム環開裂反応
- 規那塩基誘導体の合成研究(第23報) : Allo-2'-oxohexahydrochinin及びそのヒノリン核の開裂
- Synthese von Derivaten der Cinchona-Alkaloide. XXII. : Ringaufspaltung des Chinolin-Kerns der Cinchona-Alkaloide.
- On the Structure of Verticillol
- Relative Configuration of Sciadin, Dimethylsciadinonate. and Sciadinone, and Substitution of Oxygen in the Lactone Ring of Sciadin with Nitrogen
- Isolation and Structure of New Diterpenes, Dimethylsciadinonate and Sciadinone, from Sciadopitys verticillata
- A New Mast Cell Degranulating Peptide, Granuliberin-R, in the Frog (Rana rugosa) Skin
- Occurrence of Pyr-His-Pro-NH_2 in the Frog Skin
- 14. サヤエンドウより(+)-Abscisic acid,GA_およびSayanedineの単離と生理作用
- Synthese von Derivaten der Cinchona-Alkaloide. XXVI. Ableitung von 5'-Methoxydihydrocinchonamin aus Chinin. (2).
- Synthese von Derivaten der Cinchona-Alkaloide. XXV. Ableitung von 5'-Methoxydihydrocinchonamin aus Chinin. (1).