Synthesis of Lanosterol Derivatives with a Functional Group at C-32,Including an Antineoplastic Sterol, 3β-Hydroxylanost-7-en-32-oic Acid
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概要
- 論文の詳細を見る
Lanosterol derivatives with a functional group at C-32 have been synthesized from 3β-acetoxylanostan-7α-ol. The key reaction of the synthesis is the hypoiodite reaction of 3β-acetoxylanostan-7α-ol. In vitro antitumor activity testing of the lanosterol derivatives revealed that 3β-hydroxylanost-7-en-32-oic acid has antineoplastic activity.
- 公益社団法人日本薬学会の論文
- 1991-01-25
著者
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佐々木 琢磨
Cancer Research Institute Kanazawa University
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佐藤 良博
共立薬科大学名誉
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園田 よし子
Kyoritsu College of Pharmacy
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佐藤 良博
Kyoritsu College of Pharmacy
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佐藤 良博
共立薬大
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一ノ瀬 貴三子
Kyoritsu College of Pharmacy
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吉村 知子
Kyoritsu College of Pharmacy
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