The Constituents of Schizonepeta tenuifolia BRIQ. I. Structures of Two New Monoterpene Glucosides, Schizonepetosides A and B

元データ 1981-06-25 社団法人日本薬学会


Two new glucosides, named schizonepetosides A (1) and B (2), were isolated from the spikes of Schizonepeta tenuifolia (Labiatae). The structure of 1 was elucidated as (1S, 4R, 8E)-9-O-β-D-glucopyranosyl-p-menth-8 (9)-en-3-one on the basis of chemical and spectral studies. Compound 2 was identified as a glucoside possessing a dioxane ring formed by the double linkage between glucose and the aglycone, (1S, 4R, 8R)-8,9-dihydroxy-p-menth-3-one, by X-ray crystallographic analysis.


遠藤 徹 Tsumura Laboratory
田口 平八郎 Tsumura Central Research Laboratories Tsumura & Co.
吉岡 一郎 Tsumura Laboratory
飯高 洋一 Faculty of Pharmaceutical Sciences, The University of Tokyo
佐々木 博 Tsumura Laboratory
田口 平八郎 津村研究所
飯高 洋一 School Of Medicine Teikyo University
Sasaki Hidetaka Central Research Laboratories Zeria Pharmaceutical Co. Ltd.
Sasaki H Central Research Laboratories Zeria Pharmaceutical Co. Ltd.
飯高 洋一 Faculty Of Pharmaceutical Sciences The University Of Tokyo