Biologically Active Constituents of Magnolia salicifolia : Inhibitors of Induced Histamine Release from Rat Mast Cells

スポンサーリンク

概要

• 論文の詳細を見る

• The extracts of the flower buds of Magnolia salicifolia showed remarkable anti-allergy effects in passive cutaneous anaphylaxia (PCA) test. THe bioactive constituents of this medicinal drug were isolated by monitoring their activities with an in vitro bioassay system measuring inhibitory effects on induced histamine release from rat mast cells. Of the ten isolated compounds magnosalicin is a new compound of neolignan structure. In addition to the isolated compounds samples of coumarins and lignans were evaluated their biological activities with the in vitro bioassay.

• 社団法人日本薬学会の論文
• 1991-12-25

著者

• 三川 潮

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 野口 博司

  静岡県大薬

• 飯高 洋一

  Nishi-tokyo Science University

• 飯高 洋一

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• 野口 博司

  静岡県立大学薬学部

• 野口 博司

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• 海老塚 豊

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• 三川 潮

  富山医薬大薬

• 三川 潮

  Faculty Of Pharmaceuical Sciences The University Of Tokyo

• 三川 潮

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 三川 潮

  東大 薬

• 敦賀 朋子

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• 秦 堯滔

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• 中島 淳子

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• 飯高 洋一

  School Of Medicine Teikyo University

• 飯高 洋一

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 飯高 洋一

  西東京科学大学理工学部

• 中島 淳子

  Faculty Of Pharmaceutical Sciences The University Of Tokyo

• Sankawa U

  International Research Center For Traditional Medicine

• Sankawa Ushio

  (present Address)faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University

• Sankawa Ushio

  Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University

• 秦 堯滔

  Faculty Of Pharmaceutical Sciences The University Of Tokyo

• 敦賀 朋子

  Faculty Of Pharmaceutical Sciences The University Of Tokyo

• 野口 博司

  Faculty Of Pharmaceutical Sciences The University Of Tokyo

• 飯高 洋一

  Faculty Of Pharmaceutical Sciences The University Of Tokyo

関連論文

• Inhibition of Phenylalanine Ammonia-lyase by Flavonoids
• Biosynthesis of Scytalone
• 23 ^C-^Cおよび^C-^2H couplingを利用した生合成研究
• 26 イソフラボノイド生合成におけるシトクロムP-450の酸化的芳香環転位反応(口頭発表の部)
• ISOFLAVONE GLUCOSIDES EXIST AS THEIR 6"-O___--MALONYL ESTERS IN PUERARIA LOBATA AND ITS CELL SUSPENSION CULTURES
• ISOLATION, SEQUENCE AND BACTERIAL EXPRESSION OF A cDNA FOR CHALCONE SYNTHASE FROM THE CULTURED CELLS OF PUERARIA LOBATA
• Isoflavone Synthase from Cell Suspension Cultures of Pueraria lobata
• 38 クズ培養細胞におけるイソフラボノイドの生合成(口頭発表の部)
• DEOXYCHALCONE SYNTHASE FROM CELL SUSPENSION CULTURES OF ___- ___-
• 63 Aphidicolinの生合成とaphidicolane誘導体の生物活性
• NON-STEREOSPECIFIC INCORPORATION OF (1,2- ^C_2)-ACETATE INTO TROPANE ALKALOIDS IN HYOSCYAMUS ALBUS
• Inhibition of Adenosine 3', 5'-Cyclic Monophosphate Phosphodiesterase by Components of Sophora flavescens AITON
• 21 ベンザルアセトンの骨格を構築する植物ポリケタイド合成酵素の構造と機能(口頭発表の部)
• 3 植物由来新規III型ポリケタイド合成酵素の結晶構造の解明と機能改変(口頭発表の部)
• 30(C-6) 活性中心探索プローブを用いたトリテルペン合成酵素反応機構の解析(口頭発表の部)
• 微生物由来酵素による非天然型ステロイドの生産
• 4 生合成酵素の精密機能解析を基盤とする非天然型新規化合物の創出(口頭発表の部)
• スクアレン環化酵素の生合成工学と超天然型新規環状ポリプレノイドの創出 (第14回天然薬物の開発と応用シンポジウム 講演要旨集) -- (一般講演 遺伝子工学を用いた有効成分の生産)
• 4 植物ポリケタイド合成酵素の触媒機能の多様性と非天然型新規化合物ライブラリーの構築(口頭発表の部)
• The Structure of Paeoniflorigenone, A New Monoterpene isolated from Paeoniae Radix
• 2 アロエ由来新規III型ポリケタイド合成酵素におけるポリケタイド鎖長及び生成物特異性の制御(口頭発表の部)
• 73 紅麹変異株由来の新規天然色素の構造と生合成(ポスター発表の部)
• Biosynthesis of Natural Products. III. Biosynthesis of Erythroskyrine, A Coloring Matter of Penicillium islandicum SOPP.
• Metabolic Products of Fungi. XXIV. The Structure of Erythroskyrine, a Nitrogen-containing Coloring Matter of Penicillium islandicum Sopp
• 核磁気共鳴スペクトルによるビキシンの構造決定
• Inhibitors of Prostaglandin Biosynthesis from Dalbergia odorifera
• Inhibition of Prostaglandin and Leukotriene Biosynthesis by Gingerols and Diarylheptanoids
• Chemical Studies on Sophora tomentosa : the Isolation of a New Class of Isoflavonoid
• Inhibition of Adenosine 3', 5'-Cyclic Monophosphate Phosphodiesterase by Flavonoids. III
• Constituents of the Leaves of Murraya paniculata Collected in Taiwan
• The Screening of Chinese Crude Drugs for Ca^ Antagonist Activity : Identifiaction of Active Principles from the Aerial Part of Pogostemon cablin and the Fruits of Prunus mume
• Constituents of the Root Bark of Murraya paniculata Collected in Indonesia
• PURIFICATION OF 2,3-OXIDOSQUALENE / CYCLOARTENOL CYCLASE FROM PEA SEEDLINGS
• Inhibition of Adenosine 3', 5'-Cyclic Monophosphate Phosphodiesterase by Alkaloids. II
• Inhibition of Adenosine 3', 5'-Cyclic Monophosphate Phosphodiesterase by Flavonoids. II
• Inhibition of Adenosine 3', 5'-Cyclic Monophosphate Phosphodiesterase by Lignan Glucosides of Eucommia Bark
• Inhibitors of Prostaglandin Biosynthesis from Mucuna birdwoodiana(Organic,Chemical)
• THE Ca^ ANTAGONIST ACTIVITY OF LIGNANS
• Inhibitors of the Arachidonate Cascade from Allium chinense and Their Effect on in Vitro Platelet Aggregation(Organic,Chemical)
• Inhibitors of Adenosine 3',5'-Cyclic Monophosphate Phosphodiesterase in Daphne genkwa SIEB. et ZUCC(Pharmacognosy,Chemical)
• ACID-CATALYZED REARRANGEMENT OF AN EPOXY COUMARIN PHEBALOSIN THE REVISED STRUCTURE OF MURRALONGIN
• INHIBITION OF ARACHIDONATE 5-LIPOXYGENASE BY PHENOLIC COMPOUNDS
• THE ISOLATION OF A NEW CLASS OF ISOFLAVONOID METABOLITES FROM SOPHORA TOMENTOSA L.
• Digitonin-Cholesterol Complex Formation : Effects of Varying the Length of the Side-chain
• INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS FROM DALBERGIA ODORIFERA
• RADIOIMMUNOASSAY FOR THE DETERMINATION OF GINSENG SAPONIN, GINSENOSIDE RG_1
• Introduction of an Alcoholic Hydroxyl Group into 2,3-Dibenzylbutyrolactone Lignans with Oxidizing Agents and Carbon-13 Nuclear Magnetic Resonance Spectra of the Oxidation Products
• INDUCTION OF DIFFERENTIATION IN MURINE ERYTHROLEUKEMIA CELLS BY FLAVONOIDS
• Biosynthesis of Natural Products. V. Biosynthesis of Itaconitin. (2). Tracer Studies on Itaconitin
• Biosynthesis of Natural Products. IV. Biosynthesis of Itaconitin. (1). Degradation Studies on Itaconitin
• MOLECULAR CLONING OF cDNA ENCODING HUMANLANOSTEROL SYNTHASE
• Production of Polyketide Pigments in Hairy Root Cultures of Cassia Plants
• MOLECULAR CLONING OF cDNA ENCODING RAT 2,3-OXIDOSQUALENE : LANOSTEROL CYCLASE
• FISSOLDHIMINE, A NOVEL SKELETON ALKALOID FROM FISSISTIGMA OLDHAMII
• Post-Aromatic Deoxygenation in Polyketide Biosynthesis : Reduction of Aromatic Rings in the Biosyntheses of Fungal Melanin and Anthraquinone
• Purification and Properties of Squalene-2,3-epoxide Cyclases from Pea Seedlings
• Platelet Activating Factor (PAF) Antagonists Contained in Medicinal Plants : Lignans and Sesquiterpenes
• Inhibition of in Vitro Prostaglandin and Leukotriene Biosyntheses by Cinnamoyl-β-phenethylamine and N-Acyldopamine Derivatives
• Biologically Active Constituents of Melaleuca leucadendron : Inhibitors of Induced Histamine Release from Rat Mast Cells
• Biologically Active Constituents of Centipeda minima : Sesquiterpenes of Potential Anti-allergy Activity
• Biologically Active Constituents of Magnolia salicifolia : Inhibitors of Induced Histamine Release from Rat Mast Cells
• 71 多重標識化合物の生合成研究への応用
• 紅茶テアフラビンによるコレステロール生合成酵素阻害作用
• EFFECTS OF SOME PHENOLICS ON THE PROSTAGLAND IN SYNTHESIZING ENZYME SYSTEM
• Formation of Chalcones and Isoflavones by Callus Culture of Glycyrrhiza uralensis with Different Production Patterns
• Inhibitors of Cyclic AMP Phosphodiesterase in Panax ginseng C. A. MEYER and Panax japonicus C. A. MEYER
• Inhibitors of Adenosine 3', 5'-Cyclic Monophosphate Phosphodiesterase in Cassia Seed
• カルコン合成酵素(CHS)とCHS関連酵素タンパクについて
• 104(P56) コレステロール生合成律速酵素スクアレンエポキシダーゼの構造と新規酵素阻害剤(ポスター発表の部)
• Inhibition of Prostaglandin Biosynthesis by 4-O-Methylcryptochlorophaeic Acid ; : Synthesis of Monomeric Arylcarboxylic Acids for Inhibitory Activity Testing and X-Ray Analysis of 4-O-Methylcryptochlorophaeic Acid
• Hongconin, a New Naphthalene Derivative from Hong-Cong, the Rhizome of Eleutherine ameicana MERR. et HEYNE(Iridaceae)
• 2Da-2 ニンジン培養細胞におけるchalcone synthaseの精製
• STRUCTURES OF PANICULIDINES A AND B : NOVEL PRENYLINDOLES FROM MURRAYA PANICULATA
• Inhibition of Cyclic AMP Phosphodiesterase by Lignans
• PURIFICATION AND SOME PROPERTIES OF SQUALENE-2,3-EPOXIDE : LANOSTEROL CYCLASE FROM RAT LIVER
• PURIFICATION OF 2,3-OXIDOSQUALENE : β-AMYRIN CYCLASE FROM PEA SEEDLINGS
• Inhibitors of Cyclic Adenosine Monophosphate Phosphodiesterase in Polygala tenuifolid
• 24 植物培養細胞におけるフィトステロールの生合成(口頭発表の部)
• PURIFICATION AND CHARACTERIZATION OF DIHYDROGEODIN OXIDASE FROM A FUNGAL STRAIN OF ASPERGILLUS TERREUS PRODUCING (+)-GEODIN
• PARTIAL PURIFICATION AND SOME PROPERTIES OF EMODIN-O-METHYLTRANSFERASE FROM (+)-GEODIN PRODUCING STRAIN OF ASPERGILLUS TERREUS
• Biosynthesis of 2-Hexyl-5-propylresorcinol : Biosynthetic Incorporation of Deuterium from [2-^C, 2-^2H_3]-Acetate
• Biologically Active Constituents of Arnebia euchroma : Structures of New Monoterpenylbenzoquinones : Arnebinone and Arnebifuranone
• Biologically Active Constituents of Arnebia euchroma : Structure of Arnebinol, an Ansa-Type Monoterpenylbenzenoid with Inhibitory Activity on Prostaglandin Biosynthesis
• Inhibition of Adenosine 3', 5'-Cyclic Monophosphate Phosphodiesterase by Phenolic Constituents of Mulberry Tree
• Inhibitors of Cyclic AMP Phosphodiesterase in Picrasma quassioides BENNET, and Inhibitory Activities of Related β-Carboline Alkaloids
• Inhibitors of Cyclic Adenosine 3', 5'-Monophosphate Phosphodiesterase in Phyllostachys nigra MUNRO var. henonis STAPF. and Phragmites communis TRIN., and Inhibition by Related Compounds
• INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS FROM ALPINIA OFFICINARUM
• INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS FROM GINGER
• Synergistic Action of Phenolic Signal Compounds and Carbohydrates in the Induction of Virulence Gene Expression of Agrobacterium tumefaciens
• Identification of Plant Factors Inducing Virulence Gene Expression in Agrobacterium tumefaciens
• HYDROXYACETOSYRINGONE IS THE MAJOR VIRULENCE GENE ACTIVATING FACTOR IN BELLADONNA HAIRY ROOT CULTURES, AND INOSITOL ENHANCES ITS ACTIVITY
• TWO NEW ISOFLAVONOIDS FROM ECHINOSOPHORA KOREENSIS NAKAI AND THE STRUCTURE REVISION OF SOPHORONOL
• DEOXYGENATION IN THE BIOSYNTHESIS OF POLYKETIDES : MECHANISM OF BIOMIMETIC REDUCTION OF TETRAHYDROXYNAPHTHALENE
• ISOFLAVONE SYNTHASE FROM CELL SUSPENSION CULTURES OF PUERARIA LOBATA
• OLIGOSIDE PRODUCTION BY HAIRY ROOT CULTURES TRANSFORMED BY Ri PLASMIDS
• PRODUCTION OF SECONDARY MATABOLITES BY HAIRY ROOTS AND REGENERATED PLANTS TRANSFORMED WITH R1 PLASMIDS
• ムラサキイモのカルコン合成酵素
• THE BIOSYNTHESIS OF PATULIN : THE MECHANISM OF OXIDATIVE AROMATIC RING CLEAVAGE AND LOSS OF SIDE CHAIN PROTONS FROM AROMATIC INTERMEDIATES
• BIOLOGICALLY ACTIVE CONSTITUENTS OF CENTIPEDA MINIMA : ISOLATION OF A NEW PLEWOLIN ESTER AND THE ANTIALLERGY ACTIVITY OF SESQUITERPENE LACTONES
• BIOSYNTHESIS OF PATULIN; : IN VITRO CONVERSION OF GENTISYL ALCOHOL INTO PATULIN BY MICROSOMAL ENZYME(S) AND RETENTIOIN OF ONE OF THE CARBINOL PROTONS IN THIS REACTION

もっと見る 閉じる

スポンサーリンク