Biologically Active Constituents of Magnolia salicifolia : Inhibitors of Induced Histamine Release from Rat Mast Cells

元データ 1991-12-25 社団法人日本薬学会

概要

The extracts of the flower buds of Magnolia salicifolia showed remarkable anti-allergy effects in passive cutaneous anaphylaxia (PCA) test. THe bioactive constituents of this medicinal drug were isolated by monitoring their activities with an in vitro bioassay system measuring inhibitory effects on induced histamine release from rat mast cells. Of the ten isolated compounds magnosalicin is a new compound of neolignan structure. In addition to the isolated compounds samples of coumarins and lignans were evaluated their biological activities with the in vitro bioassay.

著者

三川 潮 Faculty of Pharmaceutical Sciences, University of Tokyo
野口 博司 静岡県大薬
飯高 洋一 Nishi-tokyo Science University
飯高 洋一 Faculty of Pharmaceutical Sciences, The University of Tokyo
野口 博司 静岡県立大学薬学部
野口 博司 Faculty of Pharmaceutical Sciences, The University of Tokyo
海老塚 豊 Faculty of Pharmaceutical Sciences, The University of Tokyo
三川 潮 富山医薬大薬
三川 潮 Faculty Of Pharmaceuical Sciences The University Of Tokyo
三川 潮 Faculty Of Pharmaceutical Sciences University Of Tokyo
三川 潮 東大 薬
敦賀 朋子 Faculty of Pharmaceutical Sciences, The University of Tokyo
秦 堯滔 Faculty of Pharmaceutical Sciences, The University of Tokyo
中島 淳子 Faculty of Pharmaceutical Sciences, The University of Tokyo
飯高 洋一 School Of Medicine Teikyo University
飯高 洋一 Faculty Of Pharmaceutical Sciences University Of Tokyo
飯高 洋一 西東京科学大学理工学部
中島 淳子 Faculty Of Pharmaceutical Sciences The University Of Tokyo
Sankawa U International Research Center For Traditional Medicine
Sankawa Ushio (present Address)faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
Sankawa Ushio Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
秦 堯滔 Faculty Of Pharmaceutical Sciences The University Of Tokyo
敦賀 朋子 Faculty Of Pharmaceutical Sciences The University Of Tokyo
野口 博司 Faculty Of Pharmaceutical Sciences The University Of Tokyo
飯高 洋一 Faculty Of Pharmaceutical Sciences The University Of Tokyo

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