INHIBITION OF ARACHIDONATE 5-LIPOXYGENASE BY PHENOLIC COMPOUNDS
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概要
- 論文の詳細を見る
Some cinnamoyl-β-phenethylamine derivatives, gingerols, diarylheptanoids and acyldopamines were tested for their inhibitory effects on the 5-lipoxygenase of RBL-1 cells. Compounds containing a catechol group together with a lipophilic group strongly inhibited 5-lipoxygenase. Significant inhibition was also observed in gingerols having guaiacol instead of catechol. Linoleoyl- and linolenoyl-dopamines were the strongest 5-lipoxygenase inhibitors.
- 社団法人日本薬学会の論文
- 1986-09-25
著者
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三川 潮
Faculty of Pharmaceutical Sciences, University of Tokyo
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渋谷 雅明
Faculty of Pharmaceutical Sciences, The University of Tokyo
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三川 潮
Faculty Of Pharmaceuical Sciences The University Of Tokyo
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岩上 敏
Faculty Of Pharmaceuical Sciences The University Of Tokyo
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花岡 文雄
Faculty Of Pharmaceuical Sciences The University Of Tokyo
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曽 千芳
Faculty of Pharmaceutical Sciences, University of Tokyo
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曽 千芳
Faculty Of Pharmaceutical Sciences The University Of Tokyo
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