Inhibition of Prostaglandin Biosynthesis by the Constituents of Medicinal Plants

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概要

• 論文の詳細を見る

• Hot aqueous extracts of medicinal plants used in oriental medicine were tested for inhibitory effect on prostaglandin biosynthesis in order to detect biologically active compounds present therein. Of 162 samples tested, 35 showed significant inhibition. Inhibitors of prostaglandin biosynthesis contained in Cyperus rotundus were identified as sesquiterpenes. α-Cyperone, the main inhibitor of C. rotundus, showed competitive-type inhibition with respect to the substrate, arachidonic acid.

• 公益社団法人日本薬学会の論文
• 1983-10-25

著者

• 木内 文之

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 木下 武司

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 三川 潮

  東京大学薬学部

• 渋谷 雅明

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• 三川 潮

  Faculty Of Pharmaceuical Sciences The University Of Tokyo

• 木下 武司

  Faculty Of Pharmaceutical Sciences Teikyo University

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