天然物の生合成(第10報) : Shikonin生合成におけるLeucine-^<14>C, Valine-^<14>Cの取り込みについて
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概要
- 論文の詳細を見る
Mevalonic acid (MVA)-2-^<14>C, leucine-U-^<14>C, valine-U-^<14>C and other labelled compounds listed in TABLE I were fed to Lythospermum officinalis L. var erythrorhizon MAX. to investigate incorporations into shikonin (1). Contrary to the results obtained by Zenk in the biosynthesis of alkanin, labelling result indicated that the plants were unable to utilize exogeneously administered MVA. The result of the degradation reactions of shikonin labelled by leucine-U-^<14>C and valine-U-^<14>C revealed that these amino acids were incorporated into shikonin via MVA, and are consistent with the proposed pathway of biosynthesis (path a).
- 日本生薬学会の論文
- 1976-12-20
著者
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山崎 和男
広島大学医学部
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山崎 和男
Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine
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山崎 和男
広島大薬
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三川 潮
東京大学薬学部
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山崎 和男
Institute Of Pharmaceutical Sciences Hiroshima University School Of Medicine
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柴田 承二
明治薬科大学
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海老塚 豊
東京大学薬学部生薬学植物化学教室
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