INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS FROM DALBERGIA ODORIFERA

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概要

• 論文の詳細を見る

• From the heartwood of Dalbergia odorifera T. Chen, a Chinese medicinal drug (Japanese name "Koshinko") used for the stagnation of disordered blood, five new phenolic compounds, isomucronustyrene (2) and hydroxyobtustyrene (3) (cinnamylphenol), (±)-isoduartin (6) (isoflavan), odoriflavene (7) (isoflav-3-ene) and (-)-odoricarpan (15) (pterocarpan) were isolated and their structures were elucidated on the basis of chemical and spectroscopic methods. Of the fifteen compounds isolated, the cinnamylphenols, isoflavans, isoflav-3-ene and a benzoic acid derivative inhibited prostaglandin biosynthesis more than the pterocarpan and isoflavone compounds.

• 社団法人日本薬学会の論文
• 1985-12-25

著者

• 木内 文之

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 三川 潮

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 合田 幸広

  国立医薬品食品衛生研究所

• 渋谷 雅明

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• 三川 潮

  Faculty Of Pharmaceuical Sciences The University Of Tokyo

• 市川 和雄

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 合田 幸広

  医薬品食品衛研

• 合田 幸広

  Faculty of Pharmaceutical Sciences. University of Tokyo

• 片山 円

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 片山 円

  Faculty Of Pharmaceutical Sciences University Of Tokyo

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