DEOXYGENATION IN THE BIOSYNTHESIS OF POLYKETIDES : MECHANISM OF BIOMIMETIC REDUCTION OF TETRAHYDROXYNAPHTHALENE
スポンサーリンク
概要
- 論文の詳細を見る
A biomimetic synthesis of scytalone, a simple derivative of tetralone, was reinvestigated using NMR spectroscopy. Scytalone was formed from 1,3,6,8-tetrahydroxynaphthalene (1,3,6,8-THN) by sodium borohydride reduction only in the presence of sodium methoxide. This suggests that the formation of the keto-tautomer of 1,3,6,8-THN requires an alkaline condition. The investigation of the reactive species using NMR spectroscopy clarified its structure.
- 公益社団法人日本薬学会の論文
- 1989-10-25
著者
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三川 潮
Faculty of Pharmaceutical Sciences, University of Tokyo
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海老塚 豊
Faculty of Pharmaceutical Sciences, The University of Tokyo
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三川 潮
富山医薬大薬
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三川 潮
Faculty Of Pharmaceuical Sciences The University Of Tokyo
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三川 潮
Faculty Of Pharmaceutical Sciences University Of Tokyo
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三川 潮
東大 薬
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市瀬 浩志
Faculty of Pharmaceutical Sciences, University of Tokyo
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Sankawa U
International Research Center For Traditional Medicine
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Sankawa Ushio
(present Address)faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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Sankawa Ushio
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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市瀬 浩志
Faculty Of Pharmaceutical Sciences The University Of Tokyo
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