Antioxidant and Antiviral Activities of Plastoquinones from the Brown Alga Sargassum micracanthum, and a New Chromene Derivative Converted from the Plastoquinones(Pharmacognosy)
スポンサーリンク
概要
- 論文の詳細を見る
Two plastoquinones were isolated from the methanolic extract of the brown alga Sargassum micracanthum, and these were identified as a known 2-geranylgeranyl-6-methylbenzoquinone and its hydroquinone, respectively, based on spectroscopic analysis. The absolute configuration of the secondary hydroxyl group was determined by the modified Mosher's method using the new chromene derivative converted from plastoquinones. One of the plastoquinones and the chromene exhibited significant antioxidant activities, such as an inhibitory effect on lipid peroxidation and a radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH). The benzoquinone-type compound and the chromene derivative were found to have potent antiviral activity against human cytomegalovirus (HCMV).
- 社団法人日本薬学会の論文
- 2005-02-01
著者
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SAITO Haruo
Department of Radiological Technology, School of Health Sciences, Faculty of Medicine
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三川 潮
富山医薬大薬
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三川 潮
Faculty Of Pharmaceutical Sciences University Of Tokyo
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Iwashima Makoto
Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science
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Hayashi Kyoko
Faculty Of Medicine Toyama Medical And Pharmaceutical University
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HAYASHI Toshimitsu
Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University
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SANKAWA Ushio
Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University
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Sankawa U
International Research Center For Traditional Medicine
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Sankawa Ushio
(present Address)faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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Sankawa Ushio
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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Sankawa Ushio
Faculty Of Pharmaceautical Sciences University Of Tokyo
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Ting Xiang
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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MORI Jun
Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University
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MATSUNAGA Takayuki
Toyama Prefectural Institute for Pharmaceutical Research
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SHINODA Daishi
Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University
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Mori Jun
Department Of Pharmaceutical Research Lead Chemical Co. Ltd.
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Mori Jun
The Institute Of Scientific And Industrial Research Osaka University
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Shinoda Daishi
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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Saito Haruo
Department Of Pharmaceutical Research Lead Chemical Co. Ltd.
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Saito H
Toyama Prefectural Institute For Pharmaceutical Research
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岩島 誠
Graduate School Of Medicine And Pharmaceutical Sciences University Of Toyama
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Hayashi Toshimitsu
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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Hayashi T
Faculty Of Pharmaceutical Sciences Josai University
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Mori J
Department Of Pharmaceutical Research Lead Chemical Co. Ltd.
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Hayashi K
Graduate School Of Medicine And Pharmaceutical Sciences For Research University Of Toyama
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Saito Haruo
Department Of Drug Evaluation And Toxicological Sciences Faculty Of Pharmaceutical Sciences Chiba Un
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