Effects of Structural Modification of Calcium Spirulan, a Sulfated Polysaccharide from Spirulina Platensis, on Antiviral Activity

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概要

• 論文の詳細を見る

• Calcium ion binding with the anionic part of a molecule was replaced with various metal cations and their inhibitory effects on the replication of herpes simplex virus type 1 were evaluated. Replacement of calcium ion with sodium and potassium ions maintained the antiviral activity while divalent and trivalent metal cations reduced the activity. Depolymerization of sodium spirulan with hydrogen peroxide decreased in antiviral activity as its molecular weight decreased.

• 公益社団法人日本薬学会の論文
• 2001-01-01

著者

• Lee Jung-bum

  富山大学 大学院医学薬学研究部

• Lee Jung-bum

  Faculty Of Pharmaceutical Sciences University Of Toyama

• 三川 潮

  富山医薬大薬

• 三川 潮

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• Lee J‐b

  Department Of Pharmacognosy Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical Uni

• Hayashi Kyoko

  Faculty Of Medicine Toyama Medical And Pharmaceutical University

• HAYASHI Toshimitsu

  Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University

• SANKAWA Ushio

  Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University

• Sankawa U

  International Research Center For Traditional Medicine

• Sankawa Ushio

  (present Address)faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University

• Sankawa Ushio

  Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University

• Sankawa Ushio

  Faculty Of Pharmaceautical Sciences University Of Tokyo

• HAYASHI Kyoko

  School of Medicine, Toyama Medical and Pharmaceutical University

• SRISOMPORN Preeprame

  Faculty of Pharmaceutical Sciences, Toyama Medical & Pharmaceutical University

• TANAKA Tomoyasu

  Faculty of Pharmaceutical Sciences, Toyama Medical & Pharmaceutical University

• Hayashi Toshimitsu

  Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University

• Hayashi T

  Faculty Of Pharmaceutical Sciences Josai University

• Hayashi K

  Graduate School Of Medicine And Pharmaceutical Sciences For Research University Of Toyama

• Srisomporn Preeprame

  Faculty Of Pharmaceutical Sciences Toyama Medical & Pharmaceutical University

• Tanaka Tomoyasu

  Faculty Of Pharmaceutical Sciences Toyama Medical & Pharmaceutical University

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