Evaluation of an Edible Blue-Green Alga, Aphanothece sacrum, for Its Inhibitory Effect on Replication of Herpes Simplex Virus Type 2 and Influenza Virus Type A
スポンサーリンク
概要
- 論文の詳細を見る
A hot-water extract of Aphanothece sacrum, an edible aquacultured blue-green alga, was found to show a remarkable inhibitory effect on the replication of enveloped viruses including herpes simplex virus type 2 (HSV-2) and influenza virus type A (IFV-A, H1N1) in vitro. The main active components were suggested to be sulfated polysaccharides in non-dialyzable portion (ASWPH). ASWPH was found to inhibit the viral adsorption to the receptor of the host cells involved in the replication process of HSV-2 and IFV-A. In addition, while the penetration stage of HSV-2 was also significantly suppressed with ASWPH, no such effect was observed in the replication of IFV-A. These results suggest that ASWPH might be useful in the prevention of infectious diseases caused by HSV-2 as well as IFV-A.
- 2010-08-23
著者
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Hayashi Kyoko
Graduate School of Medicine and Pharmaceutical Sciences for Research, University of Toyama, Japan
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Hayashi Toshimitsu
Graduate School of Medicine and Pharmaceutical Sciences for Research, University of Toyama, Japan
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Ogura Fumie
Graduate School of Medicine and Pharmaceutical Sciences for Research
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Lee Jung-Bum
Graduate School of Medicine and Pharmaceutical Sciences for Research
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KANEKIYO Kenji
Graduate School of Medicine and Pharmaceutical Sciences for Research
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Lee Jung-bum
富山大学 大学院医学薬学研究部
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Lee Jung-bum
Faculty Of Pharmaceutical Sciences University Of Toyama
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Lee J‐b
Department Of Pharmacognosy Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical Uni
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Hayashi Kyoko
Faculty Of Medicine Toyama Medical And Pharmaceutical University
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Kanekiyo Kenji
Graduate School Of Medicine And Pharmaceutical Sciences For Res.
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Hayashi Toshimitsu
Graduate School Of Medicine And Pharmaceutical Science For Research University Of Toyama
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Hayashi T
Faculty Of Pharmaceutical Sciences Josai University
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Hayashi K
Graduate School Of Medicine And Pharmaceutical Sciences For Research University Of Toyama
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Hayashi Kyoko
Graduate School Of Medicine And Pharmaceutical Sciences For Research University Of Toyama
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