2 アミノ酸熱分解物中に含まれる変異原物質 : 分離・構造・合成および生物活性

概要

論文の詳細を見る
A series of amino acids was pyrolyzed and was tested their mutagenicity. Basic fractions from pyrolysates of tryptophan, glutamic acid, ornitine, and serine showed potent mutagenicities to Salmonella typhymurium TA 98. The active principles from tryptophan pyrolysate were identified as 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) and 3-amino-1-methyl-5H-pyrido-[4,3-b]indole (Trp-P-2). The active principles from glutamic acid were also identified as 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1) and 2-amino-dipyrido[1,2-a:3',2'-d]imidazole (Glu-P-2).
天然有機化合物討論会の論文
1978-08-22