Differentiation-Inducing Effect of Magnolialide, a 1β-Hydroxyeudesmanolide Isolated from Cichorium intybus, on Human Leukemia Cells

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概要

• 論文の詳細を見る

• Cichorium intypbus contains two 1β-hydroxyeudesmanolides, magnolialide and artesin, together with several constituents. Magnolialide inhibits the growth of several tumor cell lines and appears to induce differentiation of human leukemia HL-60 and U-937 cells to monocyte/macrophage-like cells. Another 1β-hydroxyeudesmanolide, artesin, and other consitutents were inactive. The content of magnolialide was shown to be highest in the leaves of Inje cultivar among the cultivars investigated in this study.

• 社団法人日本薬学会の論文
• 2000-08-01

著者

• LEE Kyung-Tae

  College of Pharmacy, Kyung-Hee University

• PARK Hee-Juhn

  Department of Botanical Resources, Sangji University

• MIYAMOTO Ken-ichi

  Department of Pharmacology and Pharmaceutics, Graduate School of Natural Science and Technology, Kan

• Lee Kyung-tae

  韓国

• Lee Kyung-tae

  College Of Pharmacy Kyung-hee University

• Lee Kyung-tae

  Coll. Of Pharmacy Kyung-hee Univerisity

• Park Hee-juhn

  Department Of Pharmaceutical Engineering Sangji University

• Park Hee-juhn

  韓国

• Park Hee-juhn

  Division Of Applied Plant Sciences Sangji University

• Park Hee-juhn

  Department Of Botanical Resources Sangi University

• HAN Yong-Nam

  Natural Products Research Institute, College of Pharmacy, Seoul National University

• KIM Joo-Il

  College of Pharmacy, Kyung-Hee University

• YOO Ki-Oug

  National Alpine Agricultural Experiment Station

• Lee Kyung

  College Of Pharmacy Kyung Hee University

• Lee Kyung-won

  韓国

• Han Yong-nam

  Natural Products Research Institute Seoul National University

• Park Hee-joun

  Department Of Botanical Resources Sangji University

• Miyamoto Ken-ichi

  Department Of Hospital Pharmacy School Of Medicine Kanazawa University

• Miyaamoto Ken-ichi

  Department Of Medical Informatics Graduate School Of Medical Science Kanazawa University

• Miyamoto Ken-ichi

  Graduate School Of Natural Science And Technology Kanazawa University

• Miyamoto K

  Kanazawa Univ. Hospital Ishikawa Jpn

• Kim Joo-il

  College Of Pharmacy Kyung-hee University

• Han Yong-nam

  Natural Products Research Institute College Of Pharmacy Seoul National University

• Miyamoto Ken-ichi

  Department Of Applied Pharmacology Faculty Of Pharmaceutical Sciences Hokuriku University

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