A New Flavanone Glycoside from the Dried Immature Fruits of Poncirus trifoliata

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概要

• 論文の詳細を見る

• A new flavanone glycoside, (2R)-5-hydroxy-4'-methoxyflavanone-7-O-{β-glucopyranosyl-(1→2)-β-glucopyranoside} (1), was isolated from the EtOAc extract of dried immature fruit of Poncirus trifoliata, together with three known compounds, (2S)-poncirin (2), (2S)-naringin (3), and (2S)-poncirenin (4). The structure of compound 1 was elucidated by spectroscopic data analysis, including 1D and 2D NMR experiments. Among the isolates, compound 2 exhibited considerable inhibitory activity against lipopolysaccharide (LPS)-induced prostaglandin E_2 (PGE_2) and interleukin-6 (IL-6) production, and mRNA expression in RAW 264.7 murine macrophage cells.

• 社団法人日本薬学会の論文
• 2007-08-01

著者

• LEE Kyung-Tae

  College of Pharmacy, Kyung-Hee University

• Lee Kyung-tae

  College Of Pharmacy Kyung-hee University

• Lee Kyung-tae

  Coll. Of Medical Sci. Kyung Hee Univ.

• Lee Kyung

  College Of Pharmacy Dongdaemun-ku Hoegi-dong Kyung-hee University

• Lee Kyung-tae

  Department Of Pharmacological Biochemistry College Of Pharmacy Kyung Hee University

• Kim Ji-yeon

  韓国

• Kim J‐y

  Yeungnam Univ. Taegu Kor

• Han Ah-reum

  韓国

• Han Ah-reum

  College Of Pharmacy And Center For Cell Signaling & Drug Discovery Research Ewha Womans Universi

• LEE Jun

  College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans Univers

• NAM Joo-Won

  College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans Univers

• SEO Eun-Kyoung

  College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans Univers

• KIM Jong-Bin

  College of Pharmacy, Kyung-Hee University

• LEE Ik-Soo

  College of Pharmacy and Research Institute of Drug Development, Chonnam National University

• SHIM Chang-Koo

  Department of Pharmaceutics, College of Pharmacy, Seoul National University

• Lee Jun

  Diabetes Research Center Division Of Traditional Korean Medicine (tkm) Integrated Research Korea Ins

• Kim Jong-bin

  Coll. Of Pharmacy Kyung-hee Univ.

• Kim Jong-pyung

  Laboratory Of Antioxidants Korea Research Institute Of Bioscience And Biotechnology

• Lee Ik-soo

  College Of Pharmacy And Research Institute Of Drug Development Chonnam National University

• Shim Chang-koo

  Department Of Pharmaceutics College Of Pharmacy Seoul National University

• Lee Kyung

  Department Of Biochemistry College Of Pharmacy Kyung-hee University

• Kim Jin

  Diabetic Complications Res. Center Div. Of Traditional Korean Medicine Integrated Res. Korea Inst. O

• Nam Joo-won

  Coll. Of Pharmacy Ewha Womans Univ.

• Seo Eun-kyoung

  Natural Product Chemistry Laboratory College Of Pharmacy And The Center For Cell Signaling & Dru

• Lee Jun

  韓国

• Seo Eun

  Natural Product Chemistry Laboratory College Of Pharmacy & The Center For Cell Signaling And Dru

• Lee Jun

  College Of Pharmacy Aging Tissue Bank Pusan National University

• Lee Jong-won

  College Of Pharmacy Ewha Womans University

• Lee Jun

  College Of Agriculture And Life Sciences Seoul National University

• Han Ah-reum

  Dep. Of Physiology Coll. Of Oriental Medicine Kyung Hee Univ.

• Lee Jun

  College of Agriculture and Life Science, Seoul National University, Seoul 151-742, Korea

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