Lupane Glycosides from the Leaves of Acanthopanax koreanum
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概要
- 論文の詳細を見る
Three new lupane-type saponins, acankoreosides F-H (1-3) were isolated from the methanol extract of the leaves of Acanthopanax koreanum NAKAI. The structures of these three saponins were established by chemical and spectroscopic analysis as 3α,30-dihydroxylup-20(29)-en-23,28-dioic acid 28-O-[α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl] ester (1), 3α, 30-dihydroxylup-23-al-20(29)-en-28-oic acid 28-O-[α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl] ester (2), and (20S) 3α-hydroxylup-23-al-28,29-dioic acid 28-O-[α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl] ester (3), respectively. The effects of the isolates (1-3) on the lipopolysaccharide-induced production of nitric oxide and prostaglandin E_2 were evaluated in RAW 264.7 macrophages.
- 公益社団法人日本薬学会の論文
- 2008-11-01
著者
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Lee Kyung-tae
韓国
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Lee Kyung-tae
Coll. Of Pharmacy Kyung-hee Univerisity
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Lee Kyung-tae
Department Of Life And Nanopharmaceutical Sciences College Of Pharmacy Kyung Hee University
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Lee Kyung-tae
Coll. Of Medical Sci. Kyung Hee Univ.
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Lee Kyung-tae
Department Of Biochemistry College Of Pharmacy Kyung Hee University
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Lee Kyung
College Of Pharmacy Kyung Hee University
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Lee Kyung-won
韓国
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Lee Kyung‐won
Kyung Hee Univ. Seoul Kor
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Yook Chang-soo
Dep. Of Pharmaceutical Sci. Coll. Of Pharmacy Kyung Hee Univ.
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Kim Hyoung
Bioanalysis And Biotransformation Res. Center Life Sciences Res. Div. Korea Inst. Of Sci. And Techno
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Lee Y
Dep. Of Pharmaceutical Sci. Coll. Of Pharmacy Kyung Hee Univ.
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Lee Kyung-tae
Kyung Hee University
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CHOI Hyun-Sik
Kyung Hee East-West Pharmaceutical Research Institute, Kyung Hee University
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KIM Hyoung
Life Sciences Division, Korea Institute of Science and Technology
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NAM Sang-Gil
Kyung Hee East-West Pharmaceutical Research Institute, Kyung Hee University
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KIM In-Seon
Kyung Hee East-West Pharmaceutical Research Institute, Kyung Hee University
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YOOK Chang-Soo
Kyung Hee East-West Pharmaceutical Research Institute, Kyung Hee University
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LEE Yong
Kyung Hee East-West Pharmaceutical Research Institute, Kyung Hee University
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Kim In-seon
Kyung Hee East-west Pharmaceutical Research Institute Kyung Hee University:college Of Pharmacy Kyung
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Nam Sang-gil
Kyung Hee East-west Pharmaceutical Research Institute Kyung Hee University:college Of Pharmacy Kyung
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Choi Hyun-sik
Kyung Hee East-west Pharmaceutical Research Institute Kyung Hee University:college Of Pharmacy Kyung
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Nam Sang-Gul
Kyung Hee East-West Pharmaceutical Research Institute, Kyung Hee University
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