Antimelanogenic Activity of 3,4-Dihydroxyacetophenone : Inhibition of Tyrosinase and MITF
スポンサーリンク
概要
- 論文の詳細を見る
3,4-Dihydroxyacetophenone (3,4-DHAP) was evaluated for antimelanogenic activity. The tyrosinase inhibitory action by 3,4-DHAP using mushroom tyrosinase revealed a strong inhibitory effect. To further explore this matter, inhibition of tyrosinase and melanin content was measured in B16 melanoma cells (B16 cells). Further, tyrosinase and microphthalmia transcription factor (MITF) protein levels were determined by the Western blot method. Additionally, tyrosinase and MITF protein levels were reduced by 3,4-DHAP. Our data indicate that the antimelanogenic activity of 3,4-DHAP was probably due to its inhibition of tyrosinase activity and the suppression of tyrosinase and MITF protein levels.
- 社団法人 日本農芸化学会の論文
- 2006-02-23
著者
-
Kim Myoung
Department Of Neurosurgery Seoul Paik Hospital Inje University College Of Medicine
-
LEE Jun
College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans Univers
-
Chung H
College Of Pharmacy Aging Tissue Bank Pusan National University
-
Chung Hae
College Of Pharmacy Pusan National University
-
Kim You
Department Of Internal Medicine Seoul National University College Of Medicine
-
Kim Myoung
Department Of Nursing Pusan National University
-
Kim You
Department Of Cosmetology Pusan Women's College
-
NO Jae
College of Pharmacy, Aging Tissue Bank, Pusan National University
-
No Jae
College Of Pharmacy Aging Tissue Bank Pusan National University
-
Chung Hae
College Of Pharmacy Aging Tissue Bank Pusan National University
-
Lee Jun
College Of Pharmacy Aging Tissue Bank Pusan National University
-
Kim Myoung
Department Of Computer Science Kaist
-
Lee Jun
College Of Agriculture And Life Sciences Seoul National University
-
Kim Myoung
Department Of Anesthesiology Paik Hospital Inje University
-
Lee Jun
College of Agriculture and Life Science, Seoul National University, Seoul 151-742, Korea
関連論文
- Identification of a New Cytotoxic Biflavanone from Selaginella doederleinii
- Inhibition of LPS-Induced iNOS, COX-2 and Cytokines Expression by Poncirin through the NF-κB Inactivation in RAW 264.7 Macrophage Cells(Pharmacognosy)
- A New Flavanone Glycoside from the Dried Immature Fruits of Poncirus trifoliata
- Inhibitory Effect of Green Tea on Injury to a Cultured Renal Epithelial Cell Line, LLC-PK_1
- Effectiveness of Green Tea Tannin on Rats with Chronic Renal Failure
- Antihypertensive Effect of Magnesium Lithospermate B, a Component of Salviae Miltiorrhizae Radix, in Spontaneously Hypertensive Rats
- Antimelanogenic Activity of 3,4-Dihydroxyacetophenone : Inhibition of Tyrosinase and MITF
- Inhibition of Melanogenic Activity by 4,4'-Dihydroxybiphenyl in Melanoma Cells(Biochemistry)
- 4,4'-Dihydroxybiphenyl as a New Potent Tyrosinase Inhibitor(Miscellaneous)
- Juxta-clavicular beaded lines
- Radical-scavenging activity of Wen-Pi-Tang and its component crude drugs : with special reference to the effects on nitric oxide, superoxide and peroxynitrite
- The vascular characteristics of melasma
- Modulation of Oxidative Stress and Melanogenesis by Proanthocyanidins
- Solitary eccrine syringofibroadenoma with prominent plasma cell infiltration
- Topical 5-aminolaevulinic acid photodynamic therapy for intractable palmoplantar psoriasis
- Linear lichenoid graft versus host disease : An unsual configuration following Blaschko's lines
- Friction Melanosis and Striae Distensa Caused by Stretch Training on a Bench Press
- Akinetic Mutism Responsive to Bromocriptine Following Subdural Hematoma Evacuation in a Patient With Hydrocephalus : Case Report
- Spinal Subdural Hematoma Following Intracranial Aneurysm Surgery : Four Case Reports
- Recent transplantation situation in Korea
- Glomerular crescents are responsible for chronic graft dysfunction in post-transplant IgA nephropathy
- Regression of low-grade gastric mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori : possible association with p16 hypermethylation
- 14-O-30 Abnormal Grain Growth in Tungsten Bronze Structured SBN Ceramics : Effect of Sr/Ba Ratio and Sintering Time
- Biflavone Glucosides from Ginkgo biloba Yellow Leaves
- Study on the Components of Luobuma with Peroxynitrite-Scavenging Activity
- Fast Evaluation of Join and Aggregate Conditions in Active Databases
- Protective Role of Glycyrrhizae Radix from Peroxynitrite-induced Renal Oxidative Damages
- IS-109 The efficacy of measuring intercycle variability of FSH, LH, FSH and LH ratios and E_2 In predicting ovarian reserve in normal women age 40-45years
- Fungal Melanonychia
- Becker's Nevus with Ipsilateral Breast Hypoplasia : Improvement with Spironolactone
- An Efficient Dynamic Hash Index Structure for NAND Flash Memory
- An Effective Self-Adaptive Admission Control Algorithm for Large Web Caches
- Grover's disease associated with pregnancy
- Nuchal fibroma presenting as two posterior neck masses
- Circumscribed palmar or plantar hypokeratosis : Report of a Korean case and published work review
- A New Pentacyclic Triterpenoid Glucoside from Prunus serrulata var. spontanea
- A New Phlorotannin from the Brown Alga Ecklonia stolonifera
- A Multi-Code Biorthogonal Code Keying with Constant Amplitude Coding(Wireless Communication Technologies)
- Successful treatment of granuloma annulare with topical 5-aminolaevulinic acid photodynamic therapy
- Cutaneous ciliated cyst of the inguinal area in a man
- The effect of herpesvirus infection on the expression of cell adhesion molecules on cultured human dermal microvascular endothelial cells
- Biomedical Applications of Low Temperature Atmospheric Pressure Plasmas to Cancerous Cell Treatment and Tooth Bleaching
- Temperature Monitoring System Based on Fiber Bragg Grating Arrays with a Wavelength Tunable OTDR(Optical Fibers, Cables and Fiber Devices, Recent Progress in Optoelectronics and Communications)
- Study on half-scale model test for light-frame shear wall
- Acetyl- and butyrylcholinesterase inhibitory activities of sterols and phlorotannins from Ecklonia stolonifera
- Live Donor Partial Liver Harvest for Canine Liver Transplantation : Development of an Innovative Technique for Surgical Training and Research
- I307 OBSERVATION OF LIQUID JET DISINTEGRATION UNDER DC AND AC/DC-COUPLED ELECTRIC FIELDS(Heat transfer in complex system-3)
- Sclerosing Segmental Neurofibromatosis
- Prediction of bending properties for structural glulam using optimized distributions of knot characteristics and laminar MOE
- Folliculosebaceous cystic hamartoma on the nipple
- A Protective Action of Magnesium Lithospermate B on Renal Function after Ischemia-Reperfusion of Rats and Cultured Proximal Tubular Cells
- Antihypertensive Effect of Magnesium Lithospermate B, a Component of Salviae Miltiorrhizae Radix, in Spontaneously Hypertensive Rats
- Characterization of Electrohydrodynamic Atomization of Slaked-lime/Water Slurry Discharged from a Capillary Nozzle
- 6 Both Th1 and Th2 cells are involved in the pathogenesis of asthma
- An Additional Case of Solitary Subungual Glomus Tumor Associated with Neurofibromatosis 1
- Ureteral nephrogenic adenoma in a renal allograft patient
- Primary cutaneous aggressive epidermotropic CD8^+ cytotoxic T-cell lymphoma with atypical presentation
- Central thickening of the donor posterior corneal disc in femtosecond-laser-assisted Descemet's stripping endothelial keratoplasty
- A Case of Tubular Apocrine Adenoma with Syringocystadenoma Papilliferum Arising in Nevus Sebaceus
- Lung injury induced by the pulmonary instillation of povidone-iodine in rats
- Hyperin and Quercetin Modulate Oxidative Stress-Induced Melanogenesis
- Promising antidiabetic potential of fucoxanthin isolated from the edible brown algae Eisenia bicyclis and Undaria pinnatifida
- Nevoid acanthosis nigricans localized to the umbilicus
- Development of Ultrasonic Time-of-Flight Computed Tomography for Hard Wood with Anisotropic Acoustic Property
- Modulation of Oxidative Stress by Proanthocyanidin in H2O2-Exposed Human Diploid Fibroblast Cells
- A Fabrication Method of Bimodal Porous Ceramics Using Segregation Reaction and Gas-solid Eutectic Reaction in Conjunction with Solidification of Water