Individual Patient-by-Patient Surveillance of the Antimicrobial Usage among Inpatients in Kanazawa University Hospital
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概要
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To explore appropriate antimlcrobial usage in Kanazawa University Hospital, the surveillance of antimicro-bial use on an individual patient basis was conducted and analyses of outstanding cases were made in detail. All data of inpatients between August 1^<st> and November 30^<th> 1999, who were prescribed at least one of the 11 antimicrobial injections that are frequently used at our hospital were collected by utilizing a computer database support system of the hospital. The overall usage seemed appropriate in terms of the period of use based on an antimicrobial analysis. However, an analysis on an individual-patient basis suggested some inappropriate usage/ misuse in certain cases. Imipenem was prescribed from the ophthalmology ward in more than 50% of all cases. This was found to be used as a postoperative prophylactic antibiotic. Since no antibiotic was prescribed to these patients thereafter, this usage cannot be defined as inappropriate although altemative antibiotics may be considered. Vancomycin was prescribed to some methicillin-resistant Staphylococcus aureus-negative patients. We also found some extensively prolonged usage of antimicrobials. All of these were considered to be inappropriate in regard to usage specified for insurance. After investigations of medical charts and consultations with attending physicians, these antimicorobials had been empirically prescribed. In one case, imipenem was prescribed to an imipenem-insensitive patient. A different effective antimicrobial drug should have been prescribed. In conclusion, we were able to uncover some inappropriate usage of antimicrobials in a patient-by-patient investigation. Our findings suggest that further surveillance and on-time suggestions to prescribers should result in a more appropriate administration of antimicrobials.
- 日本医療薬学会の論文
- 2001-06-10
著者
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MIYAMOTO Ken-ichi
Department of Pharmacology and Pharmaceutics, Graduate School of Natural Science and Technology, Kan
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YOKOGAWA Koichi
Department of Hospital Pharmacy, School of Medicine, Kanazawa University
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MATSUSHITA Ryo
Division of Pharmacy and Health Sciences, Graduate School of Natural Science and Technology, Kanazaw
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Matsushita Ryo
Division Of Pharmacy And Health Sciences Graduate School Of Natural Science And Technology Kanazawa
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Yokogawa Koichi
Department Of Clinical Pharmaceutics Graduate School Of Pharmaceutical Sciences Kanazawa University
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Yokogawa Koichi
Department Of Hospital Pharmacy Kanazawa University Hospital
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Fujita Shin-ichi
Central Clinical Laboratory Kanazawa University Hospital
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Miyamoto Ken-ichi
Department Of Hospital Pharmacy School Of Medicine Kanazawa University
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Miyaamoto Ken-ichi
Department Of Medical Informatics Graduate School Of Medical Science Kanazawa University
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Miyamoto Ken-ichi
Graduate School Of Natural Science And Technology Kanazawa University
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Yamamoto K
Faculty Of Pharmaceutical Sciences Josai University
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Miyamoto K
Kanazawa Univ. Hospital Ishikawa Jpn
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Shimizu Sakae
Division Of Pharmacy And Health Sciences Graduate School Of Natural Science And Technology Kanazawa
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Kimura Kazuko
Division Of Pharmacy And Health Sciences Graduate School Of Natural Science And Technology Kanazawa
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Naruhashi Kazumasa
Division of Pharmacy and Health Sciences, Graduate School of Natural Science and Technology, Kanazaw
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Asahi Mariko
Department of Hospital Pharmacy Kanazawa University Hospital
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Higuchi Yasuko
Division of Pharmacy and Health Sciences, Graduate School of Natural Science and Technology, Kanazaw
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Suzuki Nagao
Division of Pharmacy and Health Sciences, Graduate School of Natural Science and Technology, Kanazaw
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Suzuki Nagao
Division Of Pharmacy And Health Sciences Graduate School Of Natural Science And Technology Kanazawa
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Higuchi Yasuko
Division Of Pharmacy And Health Sciences Graduate School Of Natural Science And Technology Kanazawa
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Naruhashi Kazumasa
Division Of Pharmacy And Health Sciences Graduate School Of Natural Science And Technology Kanazawa
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Yokogawa Koichi
Department Of Chemistry Faculty Of Pharmaceutical Sciences Hokuriku University
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Miyamoto Ken-ichi
Department Of Applied Pharmacology Faculty Of Pharmaceutical Sciences Hokuriku University
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