Molecular Analysis of Medicinally-Used Chinese and Japanese Curcuma Based on 18S rRNA Gene and trnK Gene Sequences
スポンサーリンク
概要
- 論文の詳細を見る
Curcuma drugs have been used discriminatingly for invigorating blood circulation, promoting digestion, and as a cholagogic in China. However, there is confusion about the drug's botanical origins and clinical uses because of morphological similarity of Curcuma plants and drugs. In order to develop an ultimate identification, molecular analysis based on 18S rRNA gene and trnK gene sequences were performed on 6 Curcuma species used medicinally in China and Japan. The 18S rRNA gene sequences were found to be of 1810 bps in length. In comparison with the common sequence of C.longa, C.phaeocaulis, C.wenyujin and C.aromatica, that of C.kwangsiensis had one base substitution, and the same base difference was observed between the Chinese and the Japanese populations of C.zedoaria. The trnK gene sequences were found to span 2698-2705 bps. There wvere base substitutions, small deletions or insertions at some sites between the trnK coding region and matK region among each species. Based on the base substitutions, C.zedoaria and C.kwangsiensis specimens were divided into two groups, respectively. An identieal scqucnce was defected in C.phaeocaulis and in the Chinese population of C.zedoaria, as well as in the Japanese population of C.zedoaria and in one group of C.kwangsiensis with a purple-colored band in leaves. New taxonomic information to be used for authenticating Curcuma drugs was obtained.
- 社団法人日本薬学会の論文
- 2001-12-01
著者
-
KOMATSU Katsuko
Research Center for Ethnomedicines, Institute of Natural Medicine, Toyama Medical and Pharmaceutical
-
SASAKI Yohei
Research Center for Ethnomedicines, Institute of Natural Medicine, Toyama Medical and Pharmaceutical
-
FUSHIMI Hirotoshi
Research Institute for Wakan-Yaku (Traditional Sino-Japanese Medicines), Toyama Medical and Pharmace
-
Sasaki Y
Tohoku Pharmaceutical University
-
Sasaki Y
Institute Of Natural Medicine University Of Toyama
-
Cao Hui
Graduate School Of Information Science Nagoya University
-
Cao Hui
Institute Of Chinese Materia Medica China Academy Of Traditional Chinese Medicine
-
CAO Hui
Research Center for Ethnomedicines, Institute of Natural Medicine, Toyama Medical and Pharmaceutical
-
Komatsu Katsuko
富山大学和漢医薬学総合研究所
-
Komatsu K
Div. Of Pharmacognosy Dep. Of Medicinal Resources Inst. Of Natural Medicine Univ. Of Toyama
-
Komatsu K
Institute Of Natural Medical Toyama Medicine And Pharmaceutical University
-
Komatsu Katsuko
Division Of Pharmacognosy Department Of Medicinal Resources Institute Of Natural Medicine Toyama Med
-
Komatsu Katsuko
Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu
-
Komatsu Katsuko
Research Center For Ethnomedicines Institute Of Natural Medicine Toyama Medical And Pharmaceutical U
-
Komatsu Katsuko
Division Of Pharmacognosy Institute Of Natural Medicine University Of Toyama
-
Komatsu K
Institute Of Natural Medicine University Of Toyama
-
Fushimi Hirotoshi
Institute Of Natural Medicine University Of Toyama
-
Fushimi Hirotoshi
Div. Of Pharmacognosy Dep. Of Medicinal Resources Inst. Of Natural Medicine Univ. Of Toyama
-
Fushimi Hirotoshi
Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu
-
Cao Honghua
Institute Of Chinese Materia Medica China Academy Of Traditional Chinese Medicine
-
Sasaki Yohei
Research Center For Ethnomedicines Institute Of Natural Medicine Toyama Medical And Pharmaceutical U
-
Sasaki Youhei
Faculty Of Pharmaceutical Sciences Hoshi University
-
Sasaki Yohei
Department Of Medicinal Plant Science Hoshi University
-
Fushimi Hirotoshi
Research Center for Ethnomedicines, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
関連論文
- Rapid and Sensitive Detection of Lophophora williamsii by Loop-Mediated Isothermal Amplification
- Vasorelaxant Activity of Sappan Lignum Constituents and Extracts on Rat Aorta and Mesenteric Artery
- Molecular Analysis of Stemona Plants in China Based on Sequences of Four Chloroplast DNA Regions
- Molecular Analysis and Chemical Evaluation of Ephedra Plants in Mongolia
- Synthesis of Endomorphin-2Analogues Containing Piperidinecarboxylic Acid (Pip) and 2-Azetidinecarboxylic Acid (Aze)
- Synthesis and Biological Activity of Endomorphin-2 Analogues Containing Pro Mimics
- Survey of Glycyrrhizae Radix resources in Mongolia : chemical assessment of the underground part of Glycyrrhiza uralensis and comparison with Chinese Glycyrrhizea Radix
- Molecular Identification of "Chuanxiong" by Nucleotide Sequence and Multiplex Single Base Extension Analysis on Chloroplast trnK Gene(Pharmacognosy)
- Simultaneous Determination of Triterpene Saponins in Ginseng Drugs by High-Performance Liquid Chromatography
- Flavonoid Glycosides from Chromolaena odorata Leaves and Their in Vitro Cytotoxic Activity
- Effects of Curcuma Drugs on Vasomotion in Isolated Rat Aorta(Pharmacognosy)
- Application of PCR-RFLP and MASA Analyses on 18S Ribosomal RNA Gene Sequence for the Identification of Three Ginseng Drugs
- 18S RIBOSOMAL RNA GENE SEQUENCES OF THREE PANAX SPECIES AND THE CORRESPONDING GINSENG DRUGS
- Prediction of Cyclooxygenase Inhibitory Activity of Curcuma Rhizome from Chromatograms by Multivariate Analysis
- Inhibitory effect of Yunnan traditional medicines on hepatitis C viral polymerase
- Constituents of the seeds of Glycyrrhiza uralensis
- Gauss-Newton Particle Filter(Systems and Control)
- Sequence Analysis of Chinese and Japanese Curcuma Drugs on the 18S rRNA Gene and trnK Gene and the Application of Amplification-Refractory Mutation System Analysis for Their Authentication
- Molecular Analysis of Medicinally-Used Chinese and Japanese Curcuma Based on 18S rRNA Gene and trnK Gene Sequences
- Pharmacognostical Studies of the Chinese Folk Medicines, "Zhang ya cai(〔ショウ〕牙菜)" and "Qing ye dan(青葉胆)"
- Pharmacognostical Studies on the Traditional Drugs Used by Chinese Minority Race Called "Yi" (III) : On "Xuory" Derived from Genus Hemerocallis Plants (2)
- Retrieval-Combination法を用いた単眼画像からの3次元人物姿勢推定
- Fast Human Pose Retrieval Using Approximate Chamfer Distance (特集:電気関係学会東海支部連合大会)
- COMBINING GLOBAL AND SIMPLIFIED PARTS-BASED APPROACH TO ESTIMATE HUMAN BODY CONFIGURATION(International Workshop on Advanced Image Technology 2005)
- Pharmacognostical Studies on the Chinese Crude Drug"Fu pen zi"(覆盆子)-6-On Botanical Origin of"Fu pen zi"from Korea-3-
- Pharmacognostical Studies on the Chinese Crude Drug "Fu pen zi"-5-Botanical Origin of "Fu pen zi"from China Mainland
- Inhibitory Effects of Eleutherococcus senticosus Extracts on Amyloid β(25-35)-Induced Neuritic Atrophy and Synaptic Loss
- Identification of the Botanical Source of Stemonae Radix Based on Polymerase Chain Reaction with Specific Primers and Polymerase Chain Reaction-Restriction Fragment Length Polymorphism
- New Triterpenoid Saponins from the Roots of Sinocrassula asclepiadea
- Pharmacognostical Study on the Chinese"Qiang-huo(羌活)"On the Anatomical Characteristics of the Underground Parts of Notopterygium incisum and N.forbesii
- Synthesis and Nematocidal Activity of Diarylnonanoids Related to Malabaricones
- Development of a High Performance Liquid Chromatographic Method for Systematic Quantitative Analysis of Chemical Constituents in Rhubarb
- Synthesis and Biological Activity of Opioid Peptides Replaced Phenylalanine at Position 3 or 4 by 2, 6-Dimethylphenylalanine
- Biological Properties of Opioid Peptides Replacing Tyr at Position 1 by 2,6-Dimethyl-Tyr
- Authentication of Rhei Rhizoma(Material study)
- Rapid Detection of Panax ginseng by Loop-Mediated Isothermal Amplification and Its Application to Authentication of Ginseng(Pharmacognosy)
- Genetic Profiling of Sasa Species by Analysis of Chloroplast Intron between rbcL and ORF106 and Partial ORF106 Regions(Pharmacognosy)
- Morphological, genetic, and chemical polymorphism of Curcuma kwangsiensis
- Comparative Study of Chemical Constituents of Rhubarb from Different Origins
- Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) and Amplification Refractory Mutation System (ARMS) Analyses of Medicinally Used Rheum Species and Their Application for Identification of Rhei Rhizoma (Pharmacognosy)
- Molecular Analysis of Rheum Species Used as Rhei Rhizoma Based on the Chloroplast matK Gene Sequence and Its Application for Identification (Pharmacognosy)
- Application of Single-Nucleotide Polymorphism Analysis of the trnK Gene to the Identification of Curcuma Plants
- Axonal and Dendritic Extension by Protopanaxadiol-Type Saponins From Ginseng Drugs in SK-N-SH Cells
- Prolyl Endopeptidase Inhibitors from the Underground Part of Rhodiola sacra S. H. Fu
- Scientific basis for the anti-dementia drugs of constituents from Ashwagandha (Withania somnifera)(Chemical & Pharmacological study)
- Withanolide Derivatives from the Roots of Withania somnifera and Their Neurite Outgrowth Activities
- Protective Effect of Salvia miltiorrhiza on Angiotensin II-Induced Hypertrophic Responses in Neonatal Rat Cardiac Cells
- Trigonelline-Induced Neurite Outgrowth in Human Neuroblastoma SK-N-SH Cells
- Roles of Each Component of μ-Opioid Ligands Containing Dmt-Pyrazinones
- Synthesis and Bioactivity of Novel Type Pyrazinone Ring-Containing μ-Opioid Ligands
- Generation of a Selective Agonist for Mu-Opioid Receptors by the Dimerization of 2', 6'-Dimethyl-L-Tyrosine through Pyrazinone
- The Structure-Activity Relationship of Dmt-NH-X
- Synthesis of New Pyrazinone Ring-Containing Opioid Mimetics and Studies on Their Structure-Activity Relationship
- Stereoselective Synthesis of Unique L-Tyrosine Analogs : Development of Novel μ-Opioid Receptor Ligands
- Synthesis of Opioid Mimetics Containing a Pyrazinone Ring and Their Activities
- Synthesis of Endomorphin-2 Analogues, Studies on Their Activities for Opioid Receptors, and Three Dimensional Structure
- Anti-invasive and anti-angiogenic activities of Curcuma sp. extracts
- An Alternative Base-Pairing of Catechol-Bearing Nucleosides by Borate Formation
- Anti-inflammatory Constituents of Sappan Lignum
- In Vitro Study for Inhibition of NO Production about Constituents of Sappan Lignum(Pharmacognosy)
- Receptor Binding Properties and Antinociceptive Effects of Chimeric Peptides Consisting of a μ-Opioid Receptor Agonist and an ORL1 Receptor Antagonist(Medicinal Chemistry)
- Pharmacological Properties of Traditional Medivines. XXV. Effects of Ephedrine, Amygdalin, Glycyrrhizin, Gypsum and Their Combinations on Body Temperature and Body Fluid
- Pharmacological Properties of Traditional Medicines. XXIV. Classification of Antiasthmatics Based on Constitutional Predispositions
- Structural Studies of [2',6'-Dimethyl-L-tyrosine^1]Endomorphin-2 Analogues Containing Proline Mimics
- The Structure-Activity Relationship of [Dmt^1]Endomorphin-2 Derivatives
- The Structure-Activity Relationship of the Opioidmimetics Containing 2(1H)-Pyrazinone Ring as a Linker and Observation of Deamination during Synthesis
- Design of Opioidmimetics : Dimerization of 2', 6'-Dimethyl-L-Tyrosine
- Nociceptin and Dynorphin A Analogues with Dmp Substituted for N-Terminal Aromatic Residues
- 2',6'-Dimethylphenylalanine (Dmp) Can Mimic the N-Terminal Tyr in Opioid Peptides(Medicinal Chemistry)
- Biological Activity of Dermorphin and Deltorphin-II Analogs Replaced Phenylalanine at Position 3 by 2,6-Dimethylphenylalanine
- Pharmacognostical Studies on Chinese Herbs Derived from Berberidaceae Plants in Sichuan Province-3-On"Bajiaolian(八角蓮)"Derived from the Plants of Genus Dysosma
- Inhibitory Effects of Methanol Extracts of Herbal Medicines on Substance P-Induced Itch-Scratch Response
- Comparative study on volatile components of Nardostachys Rhizome
- 28D-01 Propolis Prevents Diabetes and Increases Life Span in NOD Mice and Inhibits the STZ-Toxicity in Rats
- Genetic Diversity of Ephedra Plants in Mongolia Inferred from Internal Transcribed Spacer Sequence of Nuclear Ribosomal DNA
- Receptor Affinity and Selectivity of Dermorphin-Related Analogs Containing 2', 6'-Dimethylphenylalanine in Position 1 or 3
- Synthesis of Bivalent Ac-RYYRIK-NH_2 Analogues and the Optimal Spacer Length for ORL1 Receptor Binding
- Glycosidic Constituents from Eupatorium fortunei Turcz.
- Phenolic Glycosides from Eupatorium fortunei Turcz.
- Botanical Origins and Quality Evaluation of Crude Drugs Derived from Citrus and Related Genera (Part 2) : Chemical and Anatomical Characters during Fruit Ripening Period of Cultivars of Citrus unshiu and C. natsudaidai
- Constituents of the seeds of Glycyrrhiza uralensis
- Pharmacognostical Studies of the Chinese Folk Medicines, "Zhang ya cai(〔ショウ〕牙菜)" and "Qing ye dan(青葉胆)"
- Pharmacognostical Study on the Chinese"Qiang-huo(羌活)"On the Anatomical Characteristics of the Underground Parts of Notopterygium incisum and N.forbesii
- Active components from Siberian ginseng (Eleutherococcus senticosus) for protection of amyloid β(25-35)-induced neuritic atrophy in cultured rat cortical neurons
- Peyote identification on the basis of differences in morphology, mescaline content, and trnL/trnF sequence between Lophophora williamsii and L. diffusa
- Pharmacognostical Studies on the Folk Medicine in Sichuan Province in China-4-On"Ye-cai-zi(野菜子)"
- Pharamacognostical Studies on the Codonopsis Plants-4-On the Botanical Origin of the Chinese Crude Drug"Dangshen(党参)"Derived from the Plants of Sect.Erectae-2-
- Pharmacognostical Studies on the Polygonatum Plants-2-On the Botanical Origins of the Crude Drug"Whangjeong(黄精)"from Korea
- Pharmacognostical Studies on the Chinese Crude Drug"Fu pen zi"(覆盆子)-6-On Botanical Origin of"Fu pen zi"from Korea-3-
- Pharmacognostical Studies on the Traditional Drugs Used by Chinese Minority Race Called "Yi" (III) : On "Xuory" Derived from Genus Hemerocallis Plants (2)
- Pharmacognostical Studies on the Chinese Crude Drug "Fu pen zi" (5) : Botanical Origin of "Fu pen zi" from China Mainland
- Pharmacognostical Studies on the Chinese Crude Drug "Shengma" (Part II) : "Shengma" Derived from Genus Cimicifuga Plants
- Pharmacognostical Studies on Chinese Herbs Derived from Berberidaceae Plants in Sichuan Province-3-On"Bajiaolian(八角蓮)"Derived from the Plants of Genus Dysosma
- Pharmacognostical Studies on the Chinese Drug"Jinyinhua(金銀花)"-3-Botanical Origins of Well Circulating Drug in China Mainland
- A Comparative Study on Swertiae Herba from Japan, Nepal, and China and Their Hypoglycemic Activities in Streptozotocin (STZ)-Induced Diabetic Rats