Comparative Study of Chemical Constituents of Rhubarb from Different Origins

スポンサーリンク

概要

• 論文の詳細を見る

• A comparative study of the pharmacologically active constituents of 24 rhubarb samples, which were identified genetically as Rheum tanguticum, 3 intraspecies groups of R. palmatum and R. officinale, was conducted using reversed-phase high performance liquid chromatography (HPLC) methods. Thirty compounds belonging to anthraquinones, anthraquinone glucosides, dianthrones, phenylbutanones, stilbenes, flavan-3-ols, procyanidins, galloylglucoses, acylglucoses, gallic acid, and polymeric procyanidins were analyzed quantitatively. The drug samples derived from the same botanical source showed similar chromatographic profiles, and the comparable specific shape that appeared in the 10-directed radar graphs constructed on the basis of the results of quantitative analysis indicated the relationship between chemical constituent patterns and genetic varieties of rhubarb samples.

• 公益社団法人日本薬学会の論文
• 2006-11-01

著者

• Omote Takayuki

  Division of Pharmacognosy, Department of Medicinal Resources, Institute of Natural Medicine, Univers

• Tanaka Ken

  Division of Pharmacognosy, Department of Medicinal Resources, Institute of Natural Medicine, Univers

• Komatsu Katsuko

  Division of Pharmacognosy, Department of Medicinal Resources, Institute of Natural Medicine, Univers

• Cai S‐q

  Department Of Natural Medicines School Of Pharmaceutical Sciences Peking University

• Cai Shao

  Department Of Natural Medicines School Of Pharmaceutical Sciences Peking University

• MESELHY Meselhy

  Department of Metabolic Engineering, Institute of Natural Medicine, Toyama Medical and Pharmaceutica

• CAI Shao-Qing

  Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University

• NAGAYAMA Yorinobu

  Division of Pharmacognosy, Department of Medicinal Resources, Institute of Natural Medicine, Univers

• LING Yun

  Yanjing Hospital

• Komatsu K

  Div. Of Pharmacognosy Dep. Of Medicinal Resources Inst. Of Natural Medicine Univ. Of Toyama

• Komatsu K

  Institute Of Natural Medical Toyama Medicine And Pharmaceutical University

• Komatsu Katsuko

  Division Of Pharmacognosy Department Of Medicinal Resources Institute Of Natural Medicine Toyama Med

• Komatsu Katsuko

  Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu

• Komatsu Katsuko

  Division Of Pharmacognosy Institute Of Natural Medicine University Of Toyama

• Meselhy Meselhy

  Department Of Pharmacognosy And Medicinal Plants Faculty Of Pharmacy Cairo University

• Meselhy Meselhy

  Department Of Cell-resources Engineering Institute Of Natural Medicine Toyama Medical And Pharmaceut

• Komatsu K

  Institute Of Natural Medicine University Of Toyama

• Tanaka Ken

  Div. Of Pharmacognosy Dep. Of Medicinal Resources Inst. Of Natural Medicine Univ. Of Toyama

• Nagayama Yorinobu

  Division Of Pharmacognosy Department Of Medicinal Resources Institute Of Natural Medicine University

• Tanaka Ken

  Division Of Pharmacognosy Department Of Medicinal Resources Institute Of Natural Medicine University

• Cai Shao-qing

  State Key Laboratory Of Natural And Biomimetic Drugs School Of Pharmaceutical Sciences Peking Univer

• Komatsu Katsuko

  Division of Parmacognosy, Department of Medicinal Resources, Institute of Natural Medicine, University of Toyama

関連論文

• Authentication of Coscinium fenestratum among the Other Menispermaceae Plants Prescribed in Thai Folk Medicines
• Molecular Analysis of Stemona Plants in China Based on Sequences of Four Chloroplast DNA Regions
• Molecular Analysis and Chemical Evaluation of Ephedra Plants in Mongolia
• Survey of Glycyrrhizae Radix resources in Mongolia : chemical assessment of the underground part of Glycyrrhiza uralensis and comparison with Chinese Glycyrrhizea Radix
• Molecular Identification of "Chuanxiong" by Nucleotide Sequence and Multiplex Single Base Extension Analysis on Chloroplast trnK Gene(Pharmacognosy)
• Simultaneous Determination of Triterpene Saponins in Ginseng Drugs by High-Performance Liquid Chromatography
• Flavonoid Glycosides from Chromolaena odorata Leaves and Their in Vitro Cytotoxic Activity
• Application of PCR-RFLP and MASA Analyses on 18S Ribosomal RNA Gene Sequence for the Identification of Three Ginseng Drugs
• 18S RIBOSOMAL RNA GENE SEQUENCES OF THREE PANAX SPECIES AND THE CORRESPONDING GINSENG DRUGS
• Prediction of Cyclooxygenase Inhibitory Activity of Curcuma Rhizome from Chromatograms by Multivariate Analysis
• A New Enzyme Immunoassay for Aconitine and Its Application to Quantitative Determination of Aconitine Levels in Plasma(Pharmacognosy)
• Inhibitory effect of Yunnan traditional medicines on hepatitis C viral polymerase
• Constituents of the seeds of Glycyrrhiza uralensis
• Transformation of shikonin by a cell-free extract of Eubacterium sp. A-44, a human intestinal bacterium
• Fern Constituents : Triterpenoids from Adiantum capillus-veneris
• Conversion of aconitine lipoaconitine by human intestinal bacteria and their antinociceptive effects in mice
• Sequence Analysis of Chinese and Japanese Curcuma Drugs on the 18S rRNA Gene and trnK Gene and the Application of Amplification-Refractory Mutation System Analysis for Their Authentication
• Molecular Analysis of Medicinally-Used Chinese and Japanese Curcuma Based on 18S rRNA Gene and trnK Gene Sequences
• Pharmacognostical Studies of the Chinese Folk Medicines, "Zhang ya cai(〔ショウ〕牙菜)" and "Qing ye dan(青葉胆)"
• Pharmacognostical Studies on the Traditional Drugs Used by Chinese Minority Race Called "Yi" (III) : On "Xuory" Derived from Genus Hemerocallis Plants (2)
• Pharmacognostical Studies on the Chinese Crude Drug"Fu pen zi"(覆盆子)-6-On Botanical Origin of"Fu pen zi"from Korea-3-
• Pharmacognostical Studies on the Chinese Crude Drug "Fu pen zi"-5-Botanical Origin of "Fu pen zi"from China Mainland
• Inhibitory Effects of Eleutherococcus senticosus Extracts on Amyloid β(25-35)-Induced Neuritic Atrophy and Synaptic Loss
• Identification of the Botanical Source of Stemonae Radix Based on Polymerase Chain Reaction with Specific Primers and Polymerase Chain Reaction-Restriction Fragment Length Polymorphism
• New Triterpenoid Saponins from the Roots of Sinocrassula asclepiadea
• Pharmacognostical Study on the Chinese"Qiang-huo(羌活)"On the Anatomical Characteristics of the Underground Parts of Notopterygium incisum and N.forbesii
• Development of a High Performance Liquid Chromatographic Method for Systematic Quantitative Analysis of Chemical Constituents in Rhubarb
• Authentication of Rhei Rhizoma(Material study)
• Rapid Detection of Panax ginseng by Loop-Mediated Isothermal Amplification and Its Application to Authentication of Ginseng(Pharmacognosy)
• Genetic Profiling of Sasa Species by Analysis of Chloroplast Intron between rbcL and ORF106 and Partial ORF106 Regions(Pharmacognosy)
• Morphological, genetic, and chemical polymorphism of Curcuma kwangsiensis
• Comparative Study of Chemical Constituents of Rhubarb from Different Origins
• Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) and Amplification Refractory Mutation System (ARMS) Analyses of Medicinally Used Rheum Species and Their Application for Identification of Rhei Rhizoma (Pharmacognosy)
• Molecular Analysis of Rheum Species Used as Rhei Rhizoma Based on the Chloroplast matK Gene Sequence and Its Application for Identification (Pharmacognosy)
• Application of Single-Nucleotide Polymorphism Analysis of the trnK Gene to the Identification of Curcuma Plants
• Scientific basis for the anti-dementia drugs of constituents from Ashwagandha (Withania somnifera)(Chemical & Pharmacological study)
• Withanolide Derivatives from the Roots of Withania somnifera and Their Neurite Outgrowth Activities
• Protective Effect of Salvia miltiorrhiza on Angiotensin II-Induced Hypertrophic Responses in Neonatal Rat Cardiac Cells
• Trigonelline-Induced Neurite Outgrowth in Human Neuroblastoma SK-N-SH Cells
• Pharmacokinetic study of Paeoniflorin Paeonimetabolin-I and Glycyrrhetic acid in humans after oral administration of Paeony Root, Glycyrrhiza and Shakuyaku-kanzo-to (Shao-Yao-Gan-Cao-Tang)
• Inhibitory Effects of the Methanol Extract of Ganoderma lucidum on Mosquito Allergy–Induced Itch-Associated Responses in Mice
• Pharmacological Properties of Traditional Medivines. XXV. Effects of Ephedrine, Amygdalin, Glycyrrhizin, Gypsum and Their Combinations on Body Temperature and Body Fluid
• Pharmacological Properties of Traditional Medicines. XXIV. Classification of Antiasthmatics Based on Constitutional Predispositions
• Fern Constituents : Adiantum cuneatum. III. Four New Triterpenoids, 4,23-Bisnor-3,4-secofilic-5(24)-en-3-al, 4,23-Bisnor-3,3-dimethoxy-3,4-secofilic-5(24)-ene, 7β, 25-Epoxyfern-9(11)-en-8α-ol and 7α, 8α-Epoxyfernan-25-ol
• FERN CONSTITUENTS : TWO NEW SECOFILICANE TRITERPENOIDS FROM ADIANTUM CUNEATUM
• Metabolism and Pharmacokinetics of Orally Administered Saikosaponin b_1 in Conventional, Germ-Free and Eubacterium sp. A-44-Infected Gnotobiote Rats
• Enzymes Responsible for the Metabolism of Saikosaponins from Eubacterium sp. A-44,a Human Intestinal Anaerobe
• Comparative study on volatile components of Nardostachys Rhizome
• Genetic Diversity of Ephedra Plants in Mongolia Inferred from Internal Transcribed Spacer Sequence of Nuclear Ribosomal DNA
• Constituents of the seeds of Glycyrrhiza uralensis
• Pharmacognostical Studies of the Chinese Folk Medicines, "Zhang ya cai(〔ショウ〕牙菜)" and "Qing ye dan(青葉胆)"
• Pharmacognostical Study on the Chinese"Qiang-huo(羌活)"On the Anatomical Characteristics of the Underground Parts of Notopterygium incisum and N.forbesii
• Comparison of contents of five ephedrine alkaloids in three official origins of Ephedra Herb in China by high-performance liquid chromatography
• Active components from Siberian ginseng (Eleutherococcus senticosus) for protection of amyloid β(25-35)-induced neuritic atrophy in cultured rat cortical neurons
• Pharmacognostical Studies on the Folk Medicine in Sichuan Province in China-4-On"Ye-cai-zi(野菜子)"
• Pharmacognostical Studies on the Polygonatum Plants-2-On the Botanical Origins of the Crude Drug"Whangjeong(黄精)"from Korea
• Pharmacognostical Studies on the Chinese Crude Drug"Fu pen zi"(覆盆子)-6-On Botanical Origin of"Fu pen zi"from Korea-3-
• Pharmacognostical Studies on Adiantum Plants (IV) : On Histotaxonomy of Series Veneri-Capilliformia and the Origins of Related Crude Drugs
• Inhibitory Effects of the Methanol Extract of Ganoderma lucidum on Mosquito Allergy-Induced Itch-Associated Responses in Mice
• Pharmacognostical Studies on the Traditional Drugs Used by Chinese Minority Race Called "Yi" (III) : On "Xuory" Derived from Genus Hemerocallis Plants (2)
• Pharmacognostical Studies on the Chinese Crude Drug "Fu pen zi" (5) : Botanical Origin of "Fu pen zi" from China Mainland
• Kampo Formulations, Chotosan, and Yokukansan, for Dementia Therapy: Existing Clinical and Preclinical Evidence

もっと見る 閉じる

スポンサーリンク